Purified Anti-Mouse IL-17A Antibody[17F3] (E-AB-F1272A)
For research use only.
Background | The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A in vivo. |
Alternate Names | Ctla9, Il17a, Interleukin-17A |
Swissprot | |
Clone No | |
Host | Mouse |
Reactivity | Mouse |
Isotype | Mouse IgG1, κ |
Application |
ICFCM
|
Conjugation | Unconjugated |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration date | 12 months |
Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®647
Elab Fluor®Violet 450
FITC
PE
PE/Cyanine 7
Unconjugated
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