Purified Mouse IgG1, κ Isotype Control[MOPC-21] (E-AB-F09793A)
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For research use only.
Conjugation: Unconjugated
APC APC/Cyanine 7 Biotin Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 Elab Fluor®Red 780 Elab Fluor®Violet 450 Elab Fluor®Violet 500 Elab Fluor®Violet 540 Elab Fluor®Violet 610 FITC None (AF/LE) PE PE/Cyanine 5.5 PE/Cyanine 7 PE/Elab Fluor®594 PerCP PerCP/Cyanine 5.5 Unconjugated Show More
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Concentration | ≥ 1 mg/mL |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Clone No. | MOPC-21 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
| Cat.No. | Product Name | Clone No. |
|---|---|---|
| E-AB-F09753A | Purified Mouse IgG3, κ Isotype Control[A112-3] | A112-3 |
| E-AB-F09783A | Purified Mouse IgM, κ Isotype Control[MM-30] | MM-30 |
| E-AB-F09813A | Purified Mouse IgG2b, κ Isotype Control[MPC-11] | MPC-11 |
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