AF/LE Purified Anti-Human IL-9 Antibody[MH9A4] (AN007820)
![AF/LE Purified Anti-Human IL-9 Antibody[MH9A4] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Alternate Names | Cytokine P, Interleukin, TCGF, IL9, HP40, IL-9, P40, Cytokine P40, Interleukin-9, P40 Cytokine, P40 T-cell and Mast Cell Growth Factor, T-cell Growth Factor P40, TCGF3, TCGFIII |
Clone No | |
Leadtime | Inquire |
Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Human IL-9 gene |
Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
Background | IL-9 is a 14 kDa cytokine originally named P40 and identified by its proliferative effects on T cell populations. The receptor, which is a heterodimer of the gamma chain portion of the IL-2 receptor and the IL-9R chain, activates Jak/STAT signaling pathways upon binding its ligand. Since the discovery of IL-9, numerous other functions have been observed. It induces Th17 and Treg differentiation in CD4+ T cells, IgE production in B cells, and the differentiation and proliferation of mast cells. IL-9 expression was initially observed in Th2 cells, but has since been found in Th17, eosinophil, and mast cells. Th9 cells, a newly discovered subset of CD4+ T cells, are characterized by the secretion of large amounts of IL-9 and IL-10. Th9 development is induced by stimulation of undifferentiated CD4+ with IL-4 and TGF beta. Th2 cells can also be driven towards a Th9 phenotype in the presence of TGF beta. |
Immunogen | Recombinant Human IL-9 protein |
Abbre | IL-9 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Purification Method | >98%, Protein A/G purified |
Isotype | Mouse IgG2b,κ |
Applications |
FCM
|
Cellular Localization |
Secreted
|
Concentration |
≥ 1 mg/mL
|
Conjugation | None (AF/LE) |
Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
Expiration Date | 12 months |
Shipping | Ice bag |
Other Clones
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Other Formats
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None (AF/LE)
Unconjugated
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