AF/LE Purified Anti-Mouse FcεRIα Antibody[MAR-1] (E-AB-F11880)
![AF/LE Purified Anti-Mouse FcεRIα Antibody[MAR-1] - 1](http://file.elabscience.com/assets/images/loading.png)
| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse bone marrow |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Isotype | Armenian Hamster IgG |
| Host | Armenian Hamster |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Immunogen | Recombinant Mouse FcεRIα protein |
| Abbre | FcεRIα |
| Synonyms | Fcr, Fcr-5, Fc-epsilon RI-alpha, fcepsilonri, FcERI, High affinity immunoglobulin epsilon receptor subunit alpha, Fce1a, Fcer1a |
| Swissprot | |
| Cellular Localization | Cell membrane |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Purification Method | >98%, Protein A/G purified |
| Clone | MAR-1 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit. |
| Cat.No. | Product Name | Clone No. |
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