APC Anti-Mouse FcεRIα Antibody[MAR-1] (E-AB-F1188UE)

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	100μg	$ 260.00	- +
	25μg	$ 72.00	- +

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Conjugation: APC

Isotype	Armenian Hamster IgG
Host	Armenian Hamster
Reactivity	Mouse
Applications	FCM
Clonality	Monoclonal
Isotype Control	APC Armenian Hamster IgG Isotype Control[PIP]
Abbre	FcεRIα
Synonyms	Fc-epsilon RI-alpha, FcERI, Fcer1a, High affinity immunoglobulin epsilon receptor subunit alpha
Swissprot	P20489
Cellular Localization	Membrane
Concentration	0.2 mg/mL
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Immunology, Innate Immunity
Clone No.	MAR-1
Conjugation	APC
Conjugation Information	APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.