APC Anti-Human/Monkey CD16 Antibody[3G8] (E-AB-F1236E)
![APC Anti-Human/Monkey CD16 Antibody[3G8] - 1](http://file.elabscience.com/assets/images/loading.png)
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For research use only.
| Alternate Names | Fc gamma receptor, Fc gamma receptor 3, FcγRIII |
| Clone | |
| Leadtime | Order now, ship in 3 days |
| Background | CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
| Abbre | CD16 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human;Rhesus;Cynomolgus |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1, κ |
| Isotype Control | APC Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications |
FCM
|
| Research Areas | Immunology;Innate Immunity |
| Cellular Localization |
Membrane
|
| Form | Liquid |
| Concentration |
5 μL/Test
|
| Conjugation | APC |
| Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 24 months |
| Shipping | Ice bag |
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