APC Anti-Mouse CD122 Antibody[TM-Beta 1] (AN00418UE)
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For research use only.
| Alternate Names | IL-2 Receptor β chain, IL-2Rβ |
| Clone | |
| Leadtime | Order now, ship in 3 days |
| Background | CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The TM-β1 antibody does inhibit IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis. |
| Abbre | CD122 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype | Rat IgG2b, κ |
| Isotype Control | APC Rat IgG2b, κ Isotype Control[LTF-2] |
| Applications |
FCM
|
| Cellular Localization |
Membrane
|
| Form | Liquid |
| Concentration |
0.2 mg/mL
|
| Conjugation | APC |
| Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 24 months |
| Shipping | Ice bag |
| Cat.No. | Product Name | Clone No. |
|---|---|---|
| E-AB-F1029UE | APC Anti-Mouse CD122/IL-2RB Antibody[5H4] | 5H4 |
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