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100Tests $ 115.00
50Tests $ 68.00
100Tests×2 $ 175.00
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For research use only.

Background CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Alternate Names Activation B7-2 antigen,  Cd86,  ETC-1,  Early T-cell costimulatory molecule 1,  T-lymphocyte activation antigen CD86
Swissprot
Clone No
Host Rat
Reactivity Mouse
Isotype Rat IgG2a, κ
Isotype Control
Application
FCM
Cellular Localization
Membrane
Form Liquid
Conjugation
APC
Conjugation information APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date 12 months
Shipping Ice bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Other Clones

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Other Formats

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APC

Biotin

Elab Fluor®488

Elab Fluor®647

Elab Fluor®Red 780

Elab Fluor®Violet 610

FITC

None (AF/LE)

PE

PE/Cyanine 5

PE/Cyanine 5.5

PE/Cyanine 7

PE/Elab Fluor®594

PerCP/Cyanine 5.5

Unconjugated

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