APC Anti-Rat CD45 Antibody[OX-1] (E-AB-F1227E)

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Size	Price	Qty
100Tests	$ 70.00	- +
50Tests	$ 48.00	- +
100Tests×2	$ 108.00	- +

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Isotype	Mouse IgG1, κ
Host	Mouse
Reactivity	Rat
Applications	FCM
Clonality	Monoclonal
Abbre	CD45
Synonyms	LCALy-5T200, Leukocyte common antigen, Ptprc, Receptor-type tyrosine-protein phosphatase C
Swissprot	P04157
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers
Clone No.	OX-1
Conjugation	APC
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.