FITC Anti-Rat CD45 Antibody[OX-1] (E-AB-F1227C)
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For research use only.
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Reactivity | Rat |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | CD45 |
| Synonyms | LCALy-5T200, Leukocyte common antigen, Ptprc, Receptor-type tyrosine-protein phosphatase C |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers |
| Clone No. | OX-1 |
| Conjugation | FITC |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro. |
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