Elab Fluor® 700 Anti-Mouse CD115/CSF-1R Antibody[AFS98] (E-AB-F1107M1)
![Elab Fluor<sup>®</sup> 700 Anti-Mouse CD115/CSF-1R Antibody[AFS98] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: Elab Fluor®700
APC Elab Fluor®700 None (AF/LE) PE Unconjugated Show More
| Isotype | Rat IgG2a, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Isotype Control | Elab Fluor® 700 Rat IgG2a, κ Isotype Control[2A3] |
| Abbre | CD115/CSF-1R |
| Synonyms | CD115, CSF-1 receptor (EC:2.7.10.1), CSF-1-R, CSF-1R, Csf1r, Csfmr, Fms, M-CSF-R, Macrophage colony-stimulating factor 1 receptor, Proto-oncogene c-Fms |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Clone No. | AFS98 |
| Conjugation | Elab Fluor®700 |
| Conjugation Information | Elab Fluor® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter). |
| Spectrum |
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| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts. |
| Cat.No. | Product Name | Clone No. |
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