Elab Fluor^® 488 Anti-Mouse CD172a/SIRPα Antibody[P84] (E-AB-F1286L)

Name: Elab Fluor® 488 Anti-Mouse CD172a/SIRPα Antibody[P84]
Brand: Elabscience
SKU: E-AB-F1286L
Price: 98.0 USD
Availability: InStock

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Elab Fluor<sup>®</sup> 488 Anti-Mouse CD172a/SIRPα Antibody[P84] - 1

Size	Price	Qty
100Tests	$ 160.00	- +
50Tests	$ 98.00	- +
100Tests×2	$ 275.00	- +

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Isotype	Rat IgG1, κ
Host	Rat
Reactivity	Mouse
Applications	FCM
Clonality	Monoclonal
Abbre	CD172a
Synonyms	BIT, CD172 antigen-like family member A, P84, PTPNS1, SHPS-1, SIRPα
Swissprot	Q64314
Cellular Localization	Membrane
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Cell Adhesion, Cell Biology, Immunology, Signal Transduction
Clone No.	P84
Conjugation	Elab Fluor^®488
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.