FITC Anti-Mouse CD172a/SIRPα Antibody[P84] (E-AB-F1286C)
![FITC Anti-Mouse CD172a/SIRPα Antibody[P84] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: FITC
Elab Fluor®488 Elab Fluor®700 FITC None (AF/LE) Unconjugated Show More
| Isotype | Rat IgG1, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | CD172a |
| Synonyms | BIT, CD172 antigen-like family member A, P84, PTPNS1, SHPS-1, SIRPα |
| Swissprot | |
| Cellular Localization | Membrane |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Adhesion, Cell Biology, Immunology, Signal Transduction |
| Clone No. | P84 |
| Conjugation | FITC |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D. |
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