FITC Anti-Human CD45 Antibody[HI30] (E-AB-F1137C)

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Cell Markers

Size	Price	Qty
100Tests	$ 64.00	- +
20Tests	$ 24.00	- +
100Tests×2	$ 98.00	- +

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Conjugation: FITC

Isotype	Mouse IgG1, κ
Host	Mouse
Reactivity	Human
Applications	FCM
Clonality	Monoclonal
Abbre	CD45
Synonyms	CD45, L-CA, Ly-5, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200
Swissprot	P08575
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Clone No.	HI30
Conjugation	FITC
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.