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100μg $ 50.00
25μg $ 20.00
100mg $ 13800.00
50mg $ 9650.00
25mg $ 5500.00
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For research use only.

Alternate Names CD45,  L-CA,  Ly-5,  Ptprc,  Receptor-type tyrosine-protein phosphatase C,  T200
Clone No
Leadtime Order now, ship in 3 days
Verified Samples Verified Samples in FCM: Human peripheral blood;Verified Samples in IHC: Human tonsil
Dilution FCM 2 μg/mL(1×105-5×105 cells);IHC 1:50-1:100
Background CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
Immunogen Recombinant Human CD45 protein
Abbre CD45
Swissprot
Host Mouse
Reactivity Human
Clonality Monoclonal
Purification Method >98%, Protein A/G purified
Isotype Mouse IgG1, κ
Applications
FCM;IHC
Research Areas Cell Biology;Immunology;Inhibitory Molecules;Innate Immunity;Neuroscience;Neuroscience Cell Markers;Stem Cells
Concentration
≥ 1 mg/mL
Conjugation Unconjugated
Storage Buffer Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Storage Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Expiration Date 12 months
Shipping Ice bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Other Clones

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Other Formats

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APC

Elab Fluor®488

Elab Fluor®647

Elab Fluor®700

Elab Fluor®Red 780

Elab Fluor®Violet 450

Elab Fluor®Violet 500

Elab Fluor®Violet 540

Elab Fluor®Violet 610

FITC

None (AF/LE)

PE

PE/Cyanine 5

PE/Cyanine 5.5

PE/Cyanine 7

PE/Elab Fluor®594

PerCP

PerCP/Cyanine 5.5

Unconjugated

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