Purified Anti-Human CD45 Antibody[HI30] (E-AB-F1137A)
![Purified Anti-Human CD45 Antibody[HI30] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: Unconjugated
APC Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 Elab Fluor®Red 780 Elab Fluor®Violet 450 Elab Fluor®Violet 500 Elab Fluor®Violet 540 FITC PE PE/Cyanine 5 PE/Cyanine 5.5 PE/Cyanine 7 PE/Elab Fluor®594 PerCP PerCP/Cyanine 5.5 Unconjugated Show More
| Verified Samples |
Verified Samples in FCM: Human peripheral blood Verified Samples in IHC: Human tonsil |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells), IHC 1:50-1:100 |
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM, IHC |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human CD45 protein |
| Abbre | CD45 |
| Synonyms | CD45, L-CA, Ly-5, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200 |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Purification Method | >98%, Protein A/G purified |
| Research Areas | Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells |
| Clone No. | HI30 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. |
| Cat.No. | Product Name | Clone No. |
|---|---|---|
| AN003580P | Purified Anti-Human CD45 Antibody[QA17A19] | QA17A19 |
| AN008850P | Purified Anti-Human CD45 Antibody[2D1] | 2D1 |
| E-AB-F13720P | Purified Anti-Human CD45 Antibody[BC8] | BC8 |
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