FITC Anti-Mouse CD279/PD-1 Antibody[29F.1A12] (E-AB-F1131UC)

Citations ({{ citationsPage.numTotal }}) Manual MSDS

Cell Markers

All	Size	Price	Qty
	100μg	$ 168.00	- +
	25μg	$ 54.00	- +

Add to cart

For research use only. Order now, ship in 3 days

Conjugation: FITC

Isotype	Rat IgG2a, κ
Host	Rat
Reactivity	Mouse
Applications	FCM
Clonality	Monoclonal
Isotype Control	FITC Rat IgG2a, κ Isotype Control[2A3]
Abbre	CD279/PD-1
Synonyms	Programmed Death-1, PD-1
Swissprot	Q02242
Cellular Localization	Membrane
Concentration	0.5 mg/mL
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Cancer Biomarkers, Immunology, Inhibitory Molecules
Clone No.	29F.1A12
Conjugation	FITC
Conjugation Information	FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.