PE/Cyanine7 Anti-Mouse CD279/PD-1 Antibody[29F.1A12] (E-AB-F1131UH)

Name: PE/Cyanine7 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]
Brand: Elabscience
SKU: E-AB-F1131UH
Price: 108.0 USD
Availability: InStock

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PE/Cyanine7 Anti-Mouse CD279/PD-1 Antibody[29F.1A12] - 1

All	Size	Price	Qty
	100μg	$ 260.00	- +
	25μg	$ 108.00	- +

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Isotype	Rat IgG2a, κ
Host	Rat
Reactivity	Mouse
Applications	FCM
Clonality	Monoclonal
Abbre	CD279/PD-1
Synonyms	Programmed Death-1, PD-1
Swissprot	Q02242
Cellular Localization	Membrane
Concentration	0.2 mg/mL
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Cancer Biomarkers, Immunology, Inhibitory Molecules
Clone No.	29F.1A12
Conjugation	PE/Cyanine 7
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.