Name: FITC Anti-Mouse Foxp3 Antibody[3G3]
Brand: Elabscience
SKU: E-AB-F1238C
Price: 144.0 USD
Availability: InStock

Isotype	Mouse IgG1, κ
Host	Mouse
Reactivity	Mouse
Applications	ICFCM
Clonality	Monoclonal
Abbre	Foxp3
Synonyms	Forkhead box protein P3, Foxp3, IPEX, JM2
Swissprot	Q99JB6
Cellular Localization	Nucleus
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Immunology
Clone No.	3G3
Conjugation	FITC
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	FOXP3 is a 50-55 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4+/CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in 'scurfy' mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity. In human, unlike in mouse, two isoforms of FOXP3 have been reported: one (FOXP3) corresponding to the canonical full-length sequence; the other (FOXP3 δ2) lacking exon 2.

Cat.No.	Product Name	Sizes
E-CK-A105	10×ACK Lysis Buffer	500mL , 200mL , 100mL
E-CK-A107	Cell Staining Buffer	500mL , 200mL , 100mL
E-CK-A108	Foxp3/Transcription Factor Staining Kit	20Assays

{{antibodyDetailsPage.numTotal}} Results

All

3G3

FJK-16s

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All

APC

Elab Fluor^®700

FITC

PE/Cyanine 5

PE/Elab Fluor^®594

PerCP/Cyanine 5.5

Unconjugated

Size	Price	Qty
100Tests	$ 228.00	- +
50Tests	$ 144.00	- +
100Tests×2	$ 342.00	- +

FITC Anti-Mouse Foxp3 Antibody[3G3] (E-AB-F1238C)