PE Anti-Human CD16 Antibody[3G8] (E-AB-F1236D)

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Size	Price	Qty
100Tests	$ 190.00	- +
20Tests	$ 75.00	- +
100Tests×2	$ 285.00	- +

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Isotype	Mouse IgG1, κ
Host	Mouse
Reactivity	Human, Rhesus, Cynomolgus
Applications	FCM
Clonality	Monoclonal
Abbre	CD16
Synonyms	Fc gamma receptor, Fc gamma receptor 3, FcγRIII
Swissprot	P08637 O75015
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Immunology, Innate Immunity
Clone No.	3G8
Conjugation	PE
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.