Name: PE Anti-Human CD172a/b Antibody[SE5A5]
Brand: Elabscience
SKU: AN00317D
Price: 97.0 USD
Availability: InStock

Isotype	Mouse IgG1, κ
Host	Mouse
Reactivity	Human
Applications	FCM
Clonality	Monoclonal
Abbre	CD172a/b
Synonyms	SIRPa, SIRPb, SIRPalpha/beta, BIT, SHPS1, MFR, P84, PTPNS1, CD172 antigen-like family member A, CD172 antigen-like family member B
Swissprot	O00241
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Clone No.	SE5A5
Conjugation	PE
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD172a, also known as signal-regulatory protein α (SIRPα), src homology 2 domain-containing phosphatase substrate-1 (SHPS1), PTPNS1, BIT, MFR, and P84, is a 75-110 kD transmembrane glycoprotein involved in receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily and is primarily expressed on monocytes/macrophages, granulocytes, dendritic cells, and neurons. CD172a serves as a substrate of activated receptor tyrosine kinases (RTKs). The interaction of CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion, and phagocytosis. CD47 (IAP) is the extracellular ligand for CD172a. SIRPα was recently demonstrated to be a specifc marker for cardiomyocytes derived from human pluripotent stem cells2.

Cat.No.	Product Name	Sizes
E-CK-A105	10×ACK Lysis Buffer	500mL , 200mL , 100mL
E-CK-A107	Cell Staining Buffer	500mL , 200mL , 100mL

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SE5A5

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APC

Elab Fluor^®700

FITC

PerCP/Cyanine 5.5

Size	Price	Qty
100Tests	$ 197.00	- +
20Tests	$ 97.00	- +
100Tests×2	$ 354.00	- +

PE Anti-Human CD172a/b Antibody[SE5A5] (AN00317D)