PE Anti-Human TCR Vα24-Jα18 Antibody[6B11] (AN00568D)
![PE Anti-Human TCR Vα24-Jα18 Antibody[6B11] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
| Isotype | Mouse IgG1 |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | TCR Vα24-Jα18 |
| Synonyms | TCR Vα24-Jα18, TCR Vα24-JαQ, invariant NKT cell, iNKT |
| Cellular Localization | Membrane |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Clone No. | 6B11 |
| Conjugation | PE |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | Encoded by the TCR Vα24-Jα18 germline configuration, Vα24-JαQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT). Vα24-JαQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential. |
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PE
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