PE Anti-Mouse CX3CR1 Antibody[SA011F11] (AN01022D)

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Size	Price	Qty
100Tests	$ 280.00	- +
50Tests	$ 156.00	- +
100Tests×2	$ 504.00	- +

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Isotype	Mouse IgG2a, κ
Host	Mouse
Reactivity	Mouse
Applications	FCM
Clonality	Monoclonal
Abbre	CX3CR1
Synonyms	Chemokine (C-X3-C motif) receptor 1, Fractalkine receptor, GPR13, CCRL1, CMKBRL1, CMKDR1, V28
Swissprot	Q9Z0D9
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Clone No.	SA011F11
Conjugation	PE
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CX3CR1 is a 40 kD, G-protein coupled receptor, with seven transmembrane regions. CX3CR1 is expressed by resident and alternatively activated macrophages (M2), a subset of monocytes, dendritic cells (DCs), NK cells, a subset of memory T cells, and mast cells. CX3CR1 is involved in cell recruitment during inflammation and participates in cell adhesion and extravasation from blood vessels. Its ligand is CX3CL1, also known as fractalkine or neurotactin. CX3CR1 is also a coreceptor for HIV1 and variations in this gene leads to increased susceptibility to HIV. In the brain, it is expressed by glial cells, which interact with CX3CL1 expressed by neurons.