PE/Cyanine5 Anti-Human/Mouse CD44 Antibody[IM7] (E-AB-F1100G)

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Size	Price	Qty
100Tests	$ 185.00	- +
20Tests	$ 75.00	- +
100Tests×2	$ 275.00	- +

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Isotype	Rat IgG2b, κ
Host	Rat
Reactivity	Human, Mouse
Applications	FCM
Clonality	Monoclonal
Abbre	CD44
Synonyms	MDU2MDU3MIC4, CD44, CD44 antigen, CDw44, Epican, LHR, PGP-1, PGP-I, Phagocytic glycoprotein 1, Phagocytic glycoprotein I
Swissprot	P15379 P16070
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Cell Adhesion, Cell Biology, Immunology, Stem Cells
Clone No.	IM7
Conjugation	PE/Cyanine 5
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.