Purified Anti-Mouse CD40 Antibody[FGK4.5/FGK45] (E-AB-F1028A)
For research use only.
Background | CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
Alternate Names | B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, Cd40, Tnfrsf5, Tumor necrosis factor receptor superfamily member 5 |
Swissprot | |
Clone No | |
Host | Rat |
Reactivity | Mouse |
Isotype | Rat IgG2a, κ |
Application |
FCM
|
Conjugation | Unconjugated |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration date | 12 months |
Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®488
Elab Fluor®647
Elab Fluor®700
Elab Fluor®Red 780
Elab Fluor®Violet 450
FITC
None (AF/LE)
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP
PerCP/Cyanine 5.5
Unconjugated
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