Purified Anti-Mouse CD40 Antibody[FGK4.5/FGK45] (E-AB-F1028A)
For research use only.
Alternate Names | B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, Cd40, Tnfrsf5, Tumor necrosis factor receptor superfamily member 5 |
Clone No | |
Leadtime | Order now, ship in 3 days |
Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
Dilution | FCM 2 μg/mL(1×10^5-5×10^5 cells) |
Background | CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
Immunogen | Recombinant Mouse CD40 protein |
Abbre | CD40 |
Swissprot | |
Host | Rat |
Reactivity | Mouse |
Clonality | Monoclonal |
Purification Method | >98%, Protein A/G purified |
Isotype | Rat IgG2a, κ |
Applications |
FCM
|
Research Areas | Cell Biology; Costimulatory Molecules; Immunology; Neuroscience; Neuroscience Cell Markers |
Concentration |
≥ 1 mg/mL
|
Conjugation | Unconjugated |
Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12 months |
Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®488
Elab Fluor®647
Elab Fluor®700
Elab Fluor®Red 780
Elab Fluor®Violet 450
FITC
None (AF/LE)
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP
PerCP/Cyanine 5.5
Unconjugated
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