PerCP Anti-Mouse CD8a Antibody[YTS 105.18] (AN00331F)

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Cell Markers

Size	Price	Qty
100Tests	$ 57.00	- +
50Tests	$ 32.00	- +
100Tests×2	$ 86.00	- +

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Conjugation: PerCP

Isotype	Rat IgG2b, κ
Host	Rat
Reactivity	Mouse
Applications	FCM
Clonality	Monoclonal
Isotype Control	PerCP Rat IgG2b, κ Isotype Control[LTF-2]
Abbre	CD8a
Synonyms	T8, Lyt2, Ly-2
Swissprot	P01731
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Clone No.	YTS 105.18
Conjugation	PerCP
Conjugation Information	PerCP is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).
Spectrum
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.