Elab Fluor® 488 Anti-Mouse CD8a Antibody[YTS 105.18] (AN00331L)
For research use only.
Conjugation: Elab Fluor®488
APC Elab Fluor®488 Elab Fluor®647 FITC PE PerCP PerCP/Cyanine 5.5 Unconjugated Show More
| Isotype | Rat IgG2b, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | CD8a |
| Synonyms | T8, Lyt2, Ly-2 |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Clone No. | YTS 105.18 |
| Conjugation | Elab Fluor®488 |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. |
| Cat.No. | Product Name | Clone No. |
|---|---|---|
| AN00408L | Elab Fluor® 488 Anti-Mouse CD8a Antibody[YTS169.4] | YTS169.4 |
| E-AB-F1104L | Elab Fluor® 488 Anti-Mouse CD8a Antibody[53-6.7] | 53-6.7 |
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