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Alternate Names Gpf480,  Adgre1,  Adhesion G protein-coupled receptor E1,  Cell surface glycoprotein F4/80,  EGF-like module receptor 1,  Emr1
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Background F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.
Abbre F4/80
Swissprot
Host Rat
Reactivity Mouse
Clonality Monoclonal
Isotype Rat IgG2b, κ
Isotype Control PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Applications
FCM
Research Areas Cell Biology;Immunology;Innate Immunity;Neuroinflammation;Neuroscience
Cellular Localization
Membrane
Form Liquid
Concentration
0.2 mg/mL
Conjugation PerCP/Cyanine 5.5
Conjugation Information PerCP/Cyanine5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).
Spectrum
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Storage This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date 24 months
Shipping Ice bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
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