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100μg $ 154.00
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100mg $ 18800.00
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For research use only.

Alternate Names LY64,  RP105,  CD180,  Ly78
Clone No
Leadtime Inquire
Verified Samples Verified Samples in FCM: Human peripheral blood lymphocytes
Dilution FCM 2 μg/mL(1×105-5×105 cells)
Background CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.
Immunogen Recombinant Human CD180 protein
Abbre CD180
Swissprot
Host Mouse
Reactivity Human
Clonality Monoclonal
Purification Method >98%, Protein A/G purified
Isotype Mouse IgG1, κ
Applications
FCM
Research Areas Immunology;Microbiology
Concentration
≥ 1 mg/mL
Conjugation Unconjugated
Storage Buffer Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Storage Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Expiration Date 12 months
Shipping Ice bag
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APC

PE

Unconjugated

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