Purified Anti-Human CD1a Antibody[HI149] (AN008270P)
For research use only.
| Alternate Names | FCB, HTA, T-cell surface antigen T6/Leu, CD1A, CD1, FCB6, HTA1, R4, T6, CD 1a, T-cell surface glycoprotein CD1a, T-cell surface antigen T6/Leu-6, T6, HTA1, a polypeptide, CD1A Antigen, CD1a molecule, cluster of differentiation 1 A, cortical thymocyte antigen CD1A, differentiation antigen CD1 alpha 3, epidermal dendritic cell marker CD1a, FCB 6, HTA 1, hTa1 thymocyte antigen, OTTHUMP00000018907, R 4, T 6 |
| Clone No | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Molt-4 |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Background | CD1a is a 49 kDa transmembrane glycoprotein in the CD1 family of glycolipid antigen-presenting MHC-like molecules. CD1a contains one Ig-like domain in its extracellular region. It is expressed by most nonhuman mammals but not by mice or rats. Complexes of CD1a with beta 2-microglobulin and endogenous glycolipids are constitutively expressed on antigen presenting cells, cortical thymocytes, and Langerhans cells. CD1a is a target of autoreactive Th22 helper T cells in the skin. |
| Immunogen | Recombinant Human CD1a protein |
| Abbre | CD1a |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Applications |
FCM
|
| Research Areas | Immunology |
| Cellular Localization |
Cell membrane, Membrane raft, Endosome membrane
|
| Tissue Specificity |
Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues.
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®488
Elab Fluor®647
Elab Fluor®700
FITC
None (AF/LE)
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP/Cyanine 5.5
Unconjugated
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