Purified Anti-Human CD226 Antibody[11A8] (E-AB-F1369A)
![Purified Anti-Human CD226 Antibody[11A8] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: Unconjugated
APC Elab Fluor®647 Elab Fluor®700 FITC PE PerCP/Cyanine 5.5 Unconjugated Show More
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human CD226 protein |
| Abbre | CD226 |
| Synonyms | PTA, DNAX accessory molecule, platelet and T cell activation antigen, TLiSA, PTA1, adhesion glycoprotein, CD226 antigen, CD226 molecule, DNAM 1, DNAM-1, DNAX accessory molecule 1, platelet and T cell activation antigen 1, T lineage specific activation antigen 1 antigen, TLiSA1, DNAM1, CD226, PTA-1, TLiSA1 |
| Swissprot | |
| Cellular Localization | Cell membrane |
| Tissue Specificity | Expressed by peripheral blood T-lymphocytes. |
| Concentration | ≥ 1 mg/mL |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Purification Method | >98%, Protein A/G purified |
| Research Areas | Immunology |
| Clone | 11A8 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | DNAM-1 (CD226) is a ~65 kD glycoprotein expressed on cell surface of T cells, NK cells, monocytes/macrophages, platelets and megakaryocytes and a subset of B cells and a member of the immunoglobulin (Ig)-superfamily containing 2 Ig-like domains of the V-set. The ligands for CD226 are the poliovirus receptor (CD155) and its family member nectin-2 (CD112), which are broadly expressed on epithelial, endothelial and neuronal cells. CD226 is physically associated with LFA-1 in NK cells and activated T cells, and involved in LFA-1-mediated signaling. |
| Cat.No. | Product Name | Clone No. |
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