Purified Anti-Human CD335 Antibody[9E2] (E-AB-F1444A)
![Purified Anti-Human CD335 Antibody[9E2] - 1](http://file.elabscience.com/assets/images/loading.png)
| Alternate Names | NKP, Activating NK receptor NK p46, FLJ99094, Lymphocyte antigen 94, Lymphocyte antigen 94 homolog (activating NK receptor, NCT1, NCTR1, NK cell activating receptor, NK p46), NCR, NK-p, Natural cytotoxicity triggering receptor, hNKp, CD335, LY94, NK-p46, NKP46, NCR1, hNKp46, Lymphocyte antigen 94 homolog, Natural cytotoxicity triggering receptor 1, Natural killer cell p46-related protein, NK cell-activating receptor, NCR1 |
| Clone | |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Background | CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family which triggers cytotoxicity in NK cells. CD335 is directly involved in target cell recognition and lysis, and is exclusively expressed on CD3-CD56+ NK cells, suggesting it is a universal marker for NK cells. NKp46, along with NKp30 and NKp44, is referred to as a natural cytoxicity receptor (NCR) and plays a very important role in killing virus-infected tumor cells and MHC-class I-unprotected cells. |
| Immunogen | Recombinant Human CD335 protein |
| Abbre | CD335 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications |
FCM
|
| Research Areas | Immunology;Signal Transduction;CDs |
| Cellular Localization |
Cell membrane
|
| Tissue Specificity |
Selectively expressed by both resting and activated NK cells.
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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