Purified Anti-Human CD42b Antibody[HIP1] (E-AB-F1327A)
![Purified Anti-Human CD42b Antibody[HIP1] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
| Verified Samples | Verified Samples in FCM: Human peripheral blood platelet cell |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Isotype | Mouse IgG1,κ |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human CD42b protein |
| Abbre | CD42b |
| Synonyms | DBPLT, GP1BA, BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, GPIbalpha, VWDP, Carbohydrate-Rich Portion of Platelet Membrane Glycoprotein Ib Alpha Polypeptide, Antigen CD42b alpha, CD 42b, CD42b alpha, CD42b antigen, GLYCOCALICIN, Glycoprotein Ib (platelet) alpha polypeptide, Glycoprotein Ibalpha, GP Ib alpha, GPIb alpha, MGC34595, Platelet glycoprotein Ib alpha chain, Platelet glycoprotein Ib alpha polypeptide, Platelet membrane glycoprotein 1b alpha subunit |
| Swissprot | |
| Cellular Localization | Membrane |
| Tissue Specificity | Expressed in monocyte and 144 other cell types or tissues |
| Concentration | ≥ 1 mg/mL |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Purification Method | >98%, Protein A/G purified |
| Clone No. | HIP1 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy. |
Other Clones
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Other Formats
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Unconjugated
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