Purified Anti-Human CD61 Antibody[VI-PL2] (E-AB-F11660P)
For research use only.
| Alternate Names | ITGB, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT, Integrin beta 3, ITGB3, Integrin beta-3, &, beta-3 integrin-n, beta subunit, CD 61, CD61 antigen, HPA 1, HPA 4, Integrin beta 3 (platelet glycoprotein IIIa antigen CD61), Integrin beta chain beta 3, ITB3, ITG B3, ITGB 3, ITG-B3, NAIT, Platelet fibrinogen receptor, Platelet fibrinogen receptor beta subunit, Platelet glycoprotein IIIa, Platelet glycoprotein IIIa precursor, Platelet Membrane Glycoprotein IIIa, PTP |
| Clone No | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Human peripheral blood platelet |
| Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
| Background | CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins. |
| Immunogen | Recombinant Human CD61 protein |
| Abbre | CD61 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Applications |
FCM
|
| Research Areas | Cardiovascular;Signal Transduction;Immunology;Stem Cells |
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Elab Fluor®700
Elab Fluor®Violet 450
FITC
PE
PerCP/Cyanine 5.5
Unconjugated
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