Purified Anti-Human HLA-DQ Antibody[1A3] (AN004210P)
![Purified Anti-Human HLA-DQ Antibody[1A3] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
| Alternate Names | HLADQA, HLA-DQA, HLA-DQA2, DX-ALPHA, HLA-DXA, HLADQA2, class II |
| Clone No | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Background | HLA-DQ is heterodimeric cell surface glycoprotein comprised of a 27 kD α (heavy) chain and a 32 kD β (light) chain. In contrast to other MHC class II molecules, both chains of HLA-DQ are polymorphic and the α chain shows a high degree of polymorphism. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In hematopoietic development, HLA-DR and DP are expressed first, followed by HLA-DQ. Variations in the HLA gene expression are crucial to graft survival. |
| Immunogen | Recombinant Human HLA-DQ protein |
| Abbre | HLA-DQ |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG2a, κ |
| Applications |
FCM
|
| Research Areas | Immunology |
| Cellular Localization |
Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus, trans-Golgi network membrane, Endosome membrane
|
| Tissue Specificity |
Restricted to skin Langerhans cells, although some expression at low levels may occur at the surface of B lymphoblastoid cells.
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Elab Fluor®488
Elab Fluor®647
Elab Fluor®Violet 450
FITC
PE
PE/Cyanine 5
PE/Cyanine 5.5
PerCP/Cyanine 5.5
Unconjugated
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