Elab Fluor® 488 Anti-Human HLA-DQ Antibody[1a3] (AN00421L)
![Elab Fluor<sup>®</sup> 488 Anti-Human HLA-DQ Antibody[1a3] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
| Alternate Names | MHC class II DQ monomorphic antigen, MHC II |
| Clone No | |
| Leadtime | Order now, ship in 3 days |
| Background | HLA-DQ is also known as MHC class II DQ monomorphic antigen. The major histocompatibility complex is composed of two heterodimeric glycoproteins (α and β chains) with apparent molecular weights of 27 and 32 kD. In contrast to other MHC class II molecules, both polypeptide chains of HLA-DQ are polymorphic, with the α chain showing an extremely high degree of polymorphism. HLA-DQ is expressed on B cells in the peripheral blood, and weakly expressed on activated T cells and some monocytes. HLA-DQ is absent on hematopoietic progenitors, resting T cells, erythrocytes, and platelets. HLA-DQ is expressed after HLA-DR and HLA-DP in hematopoietic development. HLA-DQ presents peptide fragments mainly from degraded intravesicular and extracellular proteins to CD4+ T lymphocytes. Specific alleles of HLA-DQ have been linked to the pathogenesis of several autoimmune diseases (including diabetes), both as a susceptibility and resistance factor depending on the particular polymorphism. |
| Abbre | HLA-DQ |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2a, κ |
| Isotype Control | E-AB-F09802L |
| Applications |
FCM
|
| Cellular Localization |
Membrane
|
| Form | Liquid |
| Concentration |
5 μL/Test
|
| Conjugation | Elab Fluor®488 |
| Conjugation Information | Elab Fluor® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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APC
Elab Fluor®488
Elab Fluor®647
Elab Fluor®Violet 450
FITC
PE
PE/Cyanine 5
PE/Cyanine 5.5
PerCP/Cyanine 5.5
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