Purified Anti-Human/Monkey CD19 Antibody[CB19] (E-AB-F10040P)
For research use only.
Conjugation: Unconjugated
APC Biotin Elab Fluor®488 Elab Fluor®700 Elab Fluor®Violet 450 Elab Fluor®Violet 500 Elab Fluor®Violet 540 FITC PE PE/Cyanine 7 PE/Elab Fluor®594 Unconjugated Show More
| Alternate Names | B-lymphocyte antigen CD, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B, B-lymphocyte surface antigen B4, B-lymphocyteantigenCD, B-lymphocyteantigenCD19, B-lymphocytesurfaceantigenB, B-lymphocytesurfaceantigenB4, B4, CD19, CD19 molecule, CVID, CVID3, Differentiation antigen CD, Differentiation antigen CD19, T-cell surface antigen Leu, T-cell surface antigen Leu-12, T-cellsurfaceantigenLeu, T-cellsurfaceantigenLeu-12 |
| Clone | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | CD19 protein is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses . CD19 is expressed throughout B cell development from pre-B cells through mature B cells, and it is commonly used as a B cell lineage marker . It is required for the responsiveness of mature B cell to antigen stimulation, germinal center development, and antibody affinity maturation . The CD19 protein associates with the B cell antigen receptor (BCR), CD81, CD38, CD21, CD22, and IFITM1/CD225/Leu13. These associations enable CD19 to amplify B cell signaling and reduce the threshold for antigen stimulation through the BCR. |
| Immunogen | Recombinant Human CD19 protein |
| Abbre | CD19 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human;Rhesus;Cynomolgus |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications |
FCM
|
| Research Areas | Immunology;Stem Cells |
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Note: Data for this module come from published literature that cites this product, displaying other products used together in the same research paper.
Searching publications using CD19 as the keyword shows that the gene above is closely associated with CD19 in research. Results are sorted in descending order of research relevance. (The displayed numbers represent the number of publications in which both terms co-occur.)
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