Purified Anti-Human SOX2 Antibody[O30-678] (AN011220P)
| Alternate Names | cb236, Delta EF2a, lcc, MGC148683, MGC2413, RGD1565646, Sex determining region Y box 2, SOX 2, SRY (sex determining region Y) box 2, SRY box containing gene 2, SRY related HMG box 2, SRY related HMG box gene 2, Transcription factor SOX 2, Transcription factor SOX-2, ysb, ANOP3, MCOPS3, Sox2, SRY-box 2, SOX, ANOP, MCOPS, SRY-box, ANOP3, MCOPS3, SOX2, SRY-box 2 |
| Clone | |
| Verified Samples | Verified Samples in FCM: NCCIT cells |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). |
| Immunogen | Recombinant Human SOX2 protein |
| Abbre | SOX2 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications |
FCM
|
| Cellular Localization |
Nuclear
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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