Purified Anti-Human TNF-α Antibody[MAb11] (AN008590P)
![Purified Anti-Human TNF-α Antibody[MAb11] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
| Alternate Names | Tumor Necrosis Factor Ligand Superfamily Member, TNFSF, TNF, DIF, TNF-alpha, TNFA, TNFSF2, TNLG1F, TNF alpha, Cachectin, Tumor Necrosis Factor, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF-a, APC1, APC1 protein, DIF, TNF-alpha, TNFA, TNFSF2, Differentiation inducing factor, Macrophage cytotoxic factor, macrophage derived, member 2, Membrane Form, monocyte derived, soluble form, sTNFA, TNF superfamily, Tumor necrosis factor alpha |
| Clone No | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Human TNF-α gene |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Background | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
| Immunogen | Recombinant Human TNF-α protein |
| Abbre | TNF-α |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Applications |
FCM
|
| Research Areas | Immunology;Signal Transduction;Cancer;Cardiovascular;Metabolism |
| Cellular Localization |
Cell membrane, Membrane, Secreted
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
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Other Formats
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Elab Fluor®647
PE/Cyanine 7
Unconjugated
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