Purified Anti-Rat Cd8a Antibody[OX-8] (E-AB-F1098A)
For research use only.
Conjugation: Unconjugated
APC Elab Fluor®488 Elab Fluor®700 FITC PE PE/Cyanine 5.5 PE/Cyanine 7 Unconjugated Show More
| Alternate Names | Cd8a, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu, T-lymphocyte differentiation antigen T8/Leu-2 |
| Clone | |
| Leadtime | inquire |
| Verified Samples | Verified Samples in FCM: Rat splenocytes |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. |
| Immunogen | Recombinant Rat Cd8a protein |
| Abbre | Cd8a |
| Swissprot | |
| Host | Mouse |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications |
FCM
|
| Cellular Localization |
Cell membrane
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Note: Data for this module come from published literature that cites this product, displaying other products used together in the same research paper.
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