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QuicKey Pro Rat SELE (E-selectin) ELISA Kit (E-OSEL-R0018)

QuicKey Pro Rat SELE (E-selectin) ELISA Kit - 1
  • QuicKey Pro Rat SELE (E-selectin) ELISA Kit - 1
  • QuicKey Pro Rat SELE (E-selectin) ELISA Kit - 2
  • QuicKey Pro Rat SELE (E-selectin) ELISA Kit - 3
All Size Price Qty
96T $ 520.00
- +
48T $ 416.00
- +
24T $ 150.00
- +
96T*5 Inquire /
96T*10 Inquire /
Add to cart

For research use only.

Product Summary

Get more sensitive and precise results with saving at least 1-2h comparing to traditional ELISA Kits. The new developed technology in house will help to accelerate your science research in a more efficient way.

Sensitivity 0.47 ng/mL
Detection Range 0.78-50 ng/mL
Sample Volume 50 μL
Total Assay Time 1 h 30 min
Reactivity Rat
Specificity This kit recognizes Rat SELE in samples. No significant cross-reactivity or interference between Rat SELE and analogues was observed.
Recovery 80%-120%
Sample Type Serum, plasma and other biological fluids
Detection Method Colorimetric method, ELISA, Sandwich
Assay Type Sandwich-ELISA
Size 96T / 48T / 24T / 96T*5 / 96T*10
Storage 2-8℃
Expiration Date 6 months
E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1)and CD62E, is an inducible adhesion molecule that is expressed on the surfaces ofstimulated vascular endothelial cells and is sometimes involved in cancer cellmetastasis. E-selectin exhibits a complex mosaic structure consisting of a largeextracellular region comprised of a lectin domain, an EGF-like domain, and a shortconsensus repeat (SCR) domain, followed by a transmembrane region and arelatively short (32 aa) cytoplasmic tail. As a member of the LEC-CAM or selectinfamily, E-selectin recognises and binds to sialylated carbohydrates includingmembers of the Lewis X and Lewis A families found on monocytes, granulocytes,and T-lymphocytes. E-selectin supports rolling and stable arrest of leukocytes onactivated vascular endothelium, and furthermore, it was indicated that it can alsotransduce an activating stimulus via the MAPK cascade into the endothelial cellduring leukocyte adhesion. E-selectin regulates adhesive interactions betweencertain blood cells and endothelium. The soluble form of E selectin (sE-selectin) isa marker of endothelial activation, and has a potential role in the pathogenesis ofcardiovascular disease as raised levels have been found in hypertension, diabetesand hyperlipidemia, although its association in established atherosclerosis diseaseand its value as a prognostic factor is more controversial. soluble E-selectin isinversely associated with the muscular component of the left ventricle, therebysuggesting that the lack of such a reparative factor may be associated with cardiacremodeling in end-stage renal disease (ESRD) patients. In addition, this adhesionmolecule appears to be involved in the pathogenesis of atherosclerosis.
Gene Alias Sele
Gene ID 25544
Uniport ID P98105
Protein Alias Sele
Research Area 心血管 免疫学
Other Clones

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