Uncoated Human α2-M (Alpha-2 Macroglobulin) ELISA Kit (E-UNEL-H0255)

Name: Uncoated Human α2-M (Alpha-2 Macroglobulin) ELISA Kit
Brand: Elabscience
SKU: E-UNEL-H0255
Price: 399.0 USD
Availability: InStock

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Uncoated Human α2-M (Alpha-2 Macroglobulin) ELISA Kit - 1

All	Size	Price	Qty
	96T*5	$ 399.00	- +
	96T*15	$ 958.00	- +

Ancillary Products Available: Ancillary Reagent Kit

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Product Summary

The new series of Elabscience^® Uncoated ELISA kits contain the basic components required for the ELISA experiments. For customers who have rich experience and can establish their own ELISA system, uncoated kit is an ideal choice to save costs.

Detection Range	15.63-1000 ng/mL
Sample Volume	100 μL
Total Assay Time	24 h
Reactivity	Human
Specificity	This kit recognizes Human α2-M in samples.No significant cross-reactivity or interference between Human α2-M and analogues was observed
Recovery	80%-120%
Sample Type	Serum, plasma
Detection Method	Colorimetric method, ELISA, Sandwich
Assay Type	Sandwich-ELISA
Size	96T5 / 96T15
Storage	-20℃
Expiration Date	12 months

Performance

Typical data

The following data was generated by the Quality Control Department, under controlled laboratory conditions (ambient temperature: 18-25 °C, relative humidity: 35-75%) using standardized procedures (TMB reaction at 37 °C in the dark for 15 minutes, followed by termination and OD measurement). These values are provided for reference only. Actual results may vary due to differences in laboratory conditions, operator technique, and equipment. Users are required to generate a standard curve using their own experimental data.

ng/mL	OD1	OD2	Mean OD	Corrected OD
1000	2.393	2.295	2.344	2.267
500	1.574	1.584	1.579	1.502
250	0.798	0.784	0.791	0.714
125	0.427	0.425	0.426	0.349
62.5	0.286	0.268	0.277	0.2
31.25	0.170	0.172	0.171	0.094
15.63	0.124	0.132	0.128	0.051
0	0.074	0.080	0.077	-

Background

The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified.