Uncoated Human CASP4 (Caspase 4) ELISA Kit (E-UNEL-H0291)
Product Summary
The new series of Elabscience® Uncoated ELISA kits contain the basic components required for the ELISA experiments. For customers who have rich experience and can establish their own ELISA system, uncoated kit is an ideal choice to save costs.
| Detection Range | 0.16-10 ng/mL |
| Sample Volume | 100 μL |
| Total Assay Time | 24 h |
| Reactivity | Human |
| Specificity | This kit recognizes Human CASP4 in samples.No significant cross-reactivity or interference between Human CASP4 and analogues was observed |
| Recovery | 80%-120% |
| Sample Type | Serum, plasma |
| Detection Method | Colorimetric method, ELISA, Sandwich |
| Assay Type | Sandwich-ELISA |
| Size | 96T*5 / 96T*15 |
| Storage | -20℃ |
| Expiration Date | 12 months |
Background
This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.
| Gene ID | 837 |
| Uniport ID | P49662 |
| Research Area | Cancer , Cell Biology , Metabolism |
| Cat.No. | Product Name | Clone No. |
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