Uncoated Mouse IL-22 (Interleukin 22) ELISA Kit (E-UNEL-M0116)
Product Summary
The new series of Elabscience® Uncoated ELISA kits contain the basic components required for the ELISA experiments. For customers who have rich experience and can establish their own ELISA system, uncoated kit is an ideal choice to save costs.
| Detection Range | 15.63-1000 pg/mL |
| Sample Volume | 100 μL |
| Total Assay Time | 24 h |
| Reactivity | Mouse |
| Specificity | This kit recognizes Mouse IL-22 in samples.No significant cross-reactivity or interference between Mouse IL-22 and analogues was observed |
| Recovery | 80%-120% |
| Sample Type | Serum, plasma |
| Detection Method | Colorimetric method, ELISA, Sandwich |
| Assay Type | Sandwich-ELISA |
| Size | 96T*5 / 96T*15 |
| Storage | -20℃ |
| Expiration Date | 12 months |
Background
Cytokine that plays a critical role in modulating tissue responses during inflammation.Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage.Unlike most of the cytokines; has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits; the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2; which in turn activates STAT3. In turn; promotes cell survival and proliferation through STAT3; ERK1/2 and PI3K/AKT pathways. Promotes phosphorylation of GSK3B at 'Ser-9' and CTTN.
| Gene ID | 50929 |
| Uniport ID | Q9JJY9 |
| Research Area | Cancer , Immunology |
| Cat.No. | Product Name | Clone No. |
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