Uncoated Mouse IL-22 (Interleukin 22) ELISA Kit (E-UNEL-M0116)

Name: Uncoated Mouse IL-22 (Interleukin 22) ELISA Kit
Brand: Elabscience
SKU: E-UNEL-M0116
Price: 260.0 USD
Availability: InStock

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Citations ({{ citationsPage.numTotal }}) Manual MSDS

Uncoated Mouse IL-22 (Interleukin 22) ELISA Kit - 1

All	Size	Price	Qty
	96T*5	$ 260.00	- +
	96T*15	$ 550.00	- +

Ancillary Products Available: Ancillary Reagent Kit

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Product Summary

The new series of Elabscience^® Uncoated ELISA kits contain the basic components required for the ELISA experiments. For customers who have rich experience and can establish their own ELISA system, uncoated kit is an ideal choice to save costs.

Detection Range	15.63-1000 pg/mL
Sample Volume	100 μL
Total Assay Time	24 h
Reactivity	Mouse
Specificity	This kit recognizes Mouse IL-22 in samples.No significant cross-reactivity or interference between Mouse IL-22 and analogues was observed
Recovery	80%-120%
Sample Type	Serum, plasma
Detection Method	Colorimetric method, ELISA, Sandwich
Assay Type	Sandwich-ELISA
Size	96T5 / 96T15
Storage	-20℃
Expiration Date	12 months

Performance

Typical data

The following data was generated by the Quality Control Department, under controlled laboratory conditions (ambient temperature: 18-25 °C, relative humidity: 35-75%) using standardized procedures (TMB reaction at 37 °C in the dark for 15 minutes, followed by termination and OD measurement). These values are provided for reference only. Actual results may vary due to differences in laboratory conditions, operator technique, and equipment. Users are required to generate a standard curve using their own experimental data.

pg/mL	OD1	OD2	Mean OD	Corrected OD
1000	2.346	2.348	2.347	2.27
500	1.570	1.600	1.585	1.508
250	0.780	0.792	0.786	0.709
125	0.413	0.431	0.422	0.345
62.5	0.269	0.281	0.275	0.198
31.25	0.173	0.173	0.173	0.096
15.63	0.130	0.120	0.125	0.048
0	0.079	0.075	0.077	-

Background

Cytokine that plays a critical role in modulating tissue responses during inflammation.Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage.Unlike most of the cytokines; has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits; the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2; which in turn activates STAT3. In turn; promotes cell survival and proliferation through STAT3; ERK1/2 and PI3K/AKT pathways. Promotes phosphorylation of GSK3B at 'Ser-9' and CTTN.