Uncoated Mouse IP-10/CXCL10 (Interferon Gamma Induced Protein 10kDa) ELISA Kit (E-UNEL-M0109)
Product Summary
The new series of Elabscience® Uncoated ELISA kits contain the basic components required for the ELISA experiments. For customers who have rich experience and can establish their own ELISA system, uncoated kit is an ideal choice to save costs.
| Detection Range | 31.25-2000 pg/mL |
| Sample Volume | 100 μL |
| Total Assay Time | 24 h |
| Reactivity | Mouse |
| Specificity | This kit recognizes Mouse IP-10/CXCL10 in samples.No significant cross-reactivity or interference between Mouse IP-10/CXCL10 and analogues was observed |
| Recovery | 80%-120% |
| Sample Type | Serum, plasma |
| Detection Method | Colorimetric method, ELISA, Sandwich |
| Assay Type | Sandwich-ELISA |
| Size | 96T*5 / 96T*15 |
| Storage | -20℃ |
| Expiration Date | 12 months |
Background
Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis; differentiation; and activation of peripheral immune cells; regulation of cell growth; apoptosis and modulation of angiostatic effects.Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites.Mechanistically; binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pathway; an increase in intracellular calcium production and actin reorganization. In turn; recruitment of activated Th1 lymphocytes occurs at sites of inflammation.Activation of the CXCL10/CXCR3 axis also plays an important role in neurons in response to brain injury for activating microglia; the resident macrophage population of the central nervous system; and directing them to the lesion site. This recruitment is an essential element for neuronal reorganization.
| Gene ID | 15945 |
| Uniport ID | P17515 |
| Research Area | Cancer , Immunology |
| Cat.No. | Product Name | Clone No. |
|---|
-
IF：{{item.impact}}
Journal：{{item.journal}} ({{item.year}})
DOI：{{item.doi}}Reactivity：{{item.species}}
Sample Type：{{item.sample_type}}
-
Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}}
