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Uncoated Porcine TNF-α (Tumor Necrosis Factor Alpha) ELISA Kit (E-UNEL-P0021)

All Size Price Qty
96T*5 $ 399.00
96T*15 $ 958.00
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For research use only.

Product Summary

The new series of Elabscience® Uncoated ELISA kits contain the basic components required for the ELISA experiments. For customers who have rich experience and can establish their own ELISA system, uncoated kit is an ideal choice to save costs.

Detection Range 31.25-2000 pg/mL
Sample Volume 100 μL
Total Assay Time 24 h
Reacitivity Porcine
Specificity This kit recognizes Porcine TNF-α in samples.No significant cross-reactivity or interference between Porcine TNF-α and analogues was observed
Recovery 80%-120%
Sample Type Serum, plasma
Detection Method Colorimetric method, ELISA, Sandwich
Size 96T*5 / 96T*15
Storage -20℃
Expiration Date 12 months
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia; Under certain conditions it can stimulate cell proliferation and induce cell differentiation.Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance.Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6.Promotes osteoclastogenesis and therefore mediates bone resorption.
Uniport ID P23563
Research Area Cancer , Cardiovascular , Metabolism , Immunology , Signal Transduction
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