ELISA Research
ELISA Research FAQs
In order to provide better customer support, we have published Answers to the most Frequently Asked Questions (FAQs) about Elabscience® products.
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The ICAM family consists of five members, designated ICAM-1 to ICAM-5. They are known to bind to leucocyte integrins CD11/CD18 such as LFA-1 and Macrophage-1 antigen, during inflammation and in immune responses. ICAM-1 which consists of five Ig-like domains, is found on the surface of leukocytes, endothelial cells and various other cells, and can be up-regulated byseveral proinflammatorycytokines. Intercellular adhesion molecule-4 (ICAM-4, LW blood group antigen), a member of the immunoglobulin superfamily expressed on red cells, contains two immunoglobulin domains of which the first domain is 30% identical to the first domains of ICAM-1,-2 and -3. Although both ICAM-1 and ICAM-4 are members of the immunoglobulin superfamily, they exhibit significant differences in cell adhesion, immune regulation, and specific biological functions. ICAM-1 primarily functions in leukocyte recruitment and inflammatory responses, while ICAM-4 is more involved in interactions between leukocytes and red blood cells, as well as in the activation and regulation of immune cells.
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the kit detects the 50kDa active heparanase subunit
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the kit detects total Thyroglobulin.
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This kit is designed to measure full length complement C5.
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sLOX-1 refers to the soluble form of LOX-1, which contains the amino acid sequence of LOX-1. Our E-EL-H1635c kit utilizes the immunogen of sLOX-1, allowing it to detect sLOX-1 in secreted samples (such as serum or plasma) as well as the membrane protein form in tissue and cell lysates.
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The protein conformation of the inactivated sample has changed, which may affect antigen-antibody binding, so we cannot guarantee ELISA results. Customers are advised to use freshly collected samples for ELISA testing.
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E-EL-H1478 Human PTHrP ELISA(Uniprot: P12272) is suitable for the detection of natural proteins. Abaloparatide is a synthetic 34-amino acid polypeptide that is an analogue of parathyroid hormone-related protein (PTHrP). However, it is necessary to consider that the difference in spatial conformation may lead to unrecognition, So the kit may not be able to detect Abaloparatide.
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At present, hamster samples have not been verified for detection in mouse kits, and it is not a same species, so testing is not recommended.
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A standard curve is not a straight line (a curve that resembles a line). It is recommended to use Origin software or other software with 4-PL (four-parameter logistic) function model to fit the standard curve. The 4-PL fitting method can reflect the linear relationship between concentration and absorbance more accurately, so as to obtain the concentration value of the substance to be measured in the sample more accurately.
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Pulmonary surfactant associated protein (SP) can be divided into SP-A, SP-B, SP-C and SP-D. SP-A is a Pulmonary Surfactant (PS). The SP-A gene contains SP-A1 and SP-A2; SP-A is mostly derived from the transcription of SP-A1.
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E-EL-M3009 Mouse Aβ1-40(Amyloid Beta 1-40) ELISA Kit detects mouse Aβ1-40, The E-EL-M3010 Mouse Aβ1-42(Amyloid Beta 1-42) ELISA Kit detected mouse Aβ1-42, and the content of Aβ1-40 was generally higher than Aβ1-42, but Aβ1-42 was closely related to the occurrence of AD disease. The Aβ monomer itself is soluble, and Aβ can aggregate into oligomers or fibers, both of which are insoluble. Thus, in the brains of AD patients, Aβ comes in three forms: soluble monomers, oligomers, and insoluble fibers. At present, most scholars believe that the neurotoxicity of Aβ is mainly manifested by its Oligomers.
