Name: APC Anti-Mouse CD115/CSF-1R Antibody[AFS98]
Brand: Elabscience
SKU: E-AB-F1107E
Price: 68.0 USD
Availability: InStock

Isotype	Rat IgG2a, κ
Host	Rat
Reactivity	Mouse
Applications	FCM
Clonality	Monoclonal
Abbre	CD115/CSF-1R
Synonyms	CD115, CSF-1 receptor (EC:2.7.10.1), CSF-1-R, CSF-1R, Csf1r, Csfmr, Fms, M-CSF-R, Macrophage colony-stimulating factor 1 receptor, Proto-oncogene c-Fms
Swissprot	P09581
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Immunology
Clone No.	AFS98
Conjugation	APC
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.

Cat.No.	Product Name	Sizes
E-CK-A105	10×ACK Lysis Buffer	500mL , 200mL , 100mL
E-CK-A107	Cell Staining Buffer	500mL , 200mL , 100mL

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AFS98

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APC

Elab Fluor^®700

Size	Price	Qty
100Tests	$ 115.00	- +
50Tests	$ 68.00	- +
100Tests×2	$ 175.00	- +

APC Anti-Mouse CD115/CSF-1R Antibody[AFS98] (E-AB-F1107E)