APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199E

Uniprot : Q62386
  • Host: Rat
  • Applications: ICFCM
  • Isotype: Rat IgG1, κ

To Purchase E-AB-F1199E

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Antigen Details

Alternate Names Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8,CTLA8
Swissprot Q62386
References
1. Fitzgerald K, et al. Eds. 2001. The Cytokine FactsBook. Academic Press San Diego.
2. Numasaki M, et al. 2002. Blood 101:2620.
3. Fossiez F, et al. 1996. J. Exp. Med. 183:2593.
4. Yao Z, et al. 1997. Cytokine 9:794.
5. Dong C. 2006. Nat. Rev. Immunol. 6:329.
6. Hofstetter HH, et al. 2005 Cell. Immunol. 237:123.

Product Details

Form Liquid
Clone No. TC11-18H10.1(See Other Available Formats)
Host Rat
Isotype Rat IgG1, κ
Isotype Control APC Rat IgG1, κ Isotype Control[HRPN] [Product E-AB-F09822E]
Reactivity Mouse
Application ICFCM (See the Application Description)
Storage Buffer PBS with 0.05% Proclin300, 1% BSA
Recommended Use Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation APC

Background

IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.

Protocols & Troubleshootings

Related Protocols Staining Intracellular Antigens for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Cat.No. Product Name Sizes
E-AB-F1199C FITC Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199C 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1199D PE Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199D 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1199E APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199E 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1199M AF647 Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199M 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1199UC FITC Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199UC 25μg, 50μg, 100μg
E-AB-F1199UD PE Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199UD 25 μg, 50 μg, 100 μg, 200 μg
E-AB-F1199UE APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199UE 25 μg, 50 μg, 100 μg, 200 μg
E-AB-F1199UM AF647 Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199UM 25 μg, 50 μg, 100 μg, 200 μg

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