Current Position:Home>>Antibodies>>FCM Antibodies>> APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199E
|Alternate Names||Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8,CTLA8|
1. Fitzgerald K, et al. Eds. 2001. The Cytokine FactsBook. Academic Press San Diego.
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6. Hofstetter HH, et al. 2005 Cell. Immunol. 237:123.
|Clone No.||TC11-18H10.1(See Other Available Formats)|
|Isotype||Rat IgG1, κ|
|Isotype Control||APC Rat IgG1, κ Isotype Control[HRPN] [Product E-AB-F09822E]|
|Application||ICFCM (See the Application Description)|
|Storage Buffer||PBS with 0.05% Proclin300, 1% BSA|
|Recommended Use||Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.|
|Shipping||Biological ice pack at 4℃|
|Stability & Storage||Keep as concentrated solution.
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
|IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.|
|Related Protocols||Staining Intracellular Antigens for Flow Cytometry|
|E-AB-F1199C||FITC Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199C||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1199D||PE Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199D||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1199E||APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199E||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1199M||AF647 Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199M||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1199UC||FITC Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199UC||25μg, 50μg, 100μg|
|E-AB-F1199UD||PE Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199UD||25 μg, 50 μg, 100 μg, 200 μg|
|E-AB-F1199UE||APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199UE||25 μg, 50 μg, 100 μg, 200 μg|
|E-AB-F1199UM||AF647 Anti-Mouse IL-17A Antibody[TC11-18H10.1] E-AB-F1199UM||25 μg, 50 μg, 100 μg, 200 μg|