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Human IL-10(Interleukin 10)ELISA Kit

Citations(90)Uniprot : P22301

  • Cat.No.:E-EL-H6154

  • Reactivity: Human

To Purchase E-EL-H6154

Size:
  • 96T
  • 48T
  • 24T
  • 96T*5
  • 96T*10
Price: $495
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Product Details

Properties

Assay type Sandwich-ELISA
Format 96T/48T
Assay time 3.5h
Detection range 1.56-100 pg/mL
Sensitivity 0.94 pg/mL
Sample type &Sample volume serum, plasma and other biological fluids; 100μL
Specificity This kit recognizes Human IL-10 in samples. No significant cross-reactivity or interference between Human IL-10 and analogues was observed.
Reproducibility Both intra-CV and inter-CV are < 10%.
Application This ELISA kit applies to the in vitro quantitative determination of Human IL-10 concentrations in serum, plasma and other biological fluids.

Test Principle

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human IL-10. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human IL-10 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human IL-10, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Human IL-10. You can calculate the concentration of Human IL-10 in the samples by comparing the OD of the samples to the standard curve.

Kit components & Storage

An unopened kit can be stored at 2-8℃ for 1 month. If the kit is not supposed to be used within 1 month, store the components separately according to the following conditions once the kit is received.
ItemSpecificationsStorage
Micro ELISA Plate(Dismountable) 96T: 8 wells ×12 strips
48T: 8 wells ×6 strips 		-20℃, 6 months
Reference Standard 96T: 2 vials
48T: 1 vial
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL
48T: 1 vial, 60 μL
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL
48T: 1 vial, 60 μL 		-20℃(Protect from light), 6 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 6 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL
HRP Conjugate Diluent 1 vial, 14 mL
Concentrated Wash Buffer (25×) 1 vial, 30 mL
Substrate Reagent 1 vial, 10 mL 2-8℃(Protect from light)
Stop Solution 1 vial, 10 mL 2-8°C
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Technical Data

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Human IL-10 were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Human IL-10 were tested on 3 different plates, 20 replicates in each plate.

  Intra-assay Precision Inter-assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean (pg/mL) 5.36 10.91 36.10 4.89 11.08 36.15
Standard deviation 0.31 0.55 1.13 0.27 0.63 1.10
CV (%) 5.87 5.06 3.13 5.61 5.73 3.05

Recovery

The recovery of Human IL-10 spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 86-102 94
EDTA plasma (n=8) 90-100 95
Cell culture media (n=8) 84-98 91

Linearity

Samples were spiked with high concentrations of Human IL-10 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

Target Information

Database LinksSwissProt:   P22301
SynonymsIL10, IL10A, CSIF, TGIF
Research AreaCancer, Immunology

Assay Procedures

elisa assay procedure 1

1. Add 100μL standard or sample to the wells. Incubate for 90 min at 37°C
elisa assay procedure 2

2. Discard the liquid, immediately add 100μL Biotinylated Detection Ab working solution to each well. Incubate for 60 min at 37°C
elisa assay procedure 3

3. Aspirate and wash the plate for 3 times
elisa assay procedure 4

4. Add 100μL HRP conjugate working solution. Incubate for 30 min at 37°C. Aspirate and wash the plate for 5 times
elisa assay procedure 5

5. Add 90μL Substrate Reagent. Incubate for 15 min at 37°C
elisa assay procedure 6

6. Add 50μL Stop Solution
elisa assay procedure 7

7. Read the plate at 450nm immediately. Calculation of the results

Citations

  1. npj Regenerative Medicine (2022) IF: 14.404
    Enforced mesenchymal stem cell tissue colonization counteracts immunopathology

    DOI: 10.1038/s41536-022-00258-z

    PMID: 36261464

    		 Sample: MSCs
  2. ALLERGY (2021) IF: 13.146
    miR-146a enhances regulatory T-cell differentiation and function in allergic rhinitis by targeting STAT5b

    DOI: 10.1111/all.15163

    PMID: 34716993

    		 Sample: PBMCs cells
  3. SCHIZOPHRENIA BULLETIN (2021) IF: 9.3059
    High Mobility Group Protein 1 and Dickkopf-Related Protein 1 in Schizophrenia and Treatment-Resistant Schizophrenia: Associations With Interleukin-6, Symptom Domains, and Neurocognitive Impairments

    DOI: 10.1093/schbul/sbaa136
    Sample: serum
  4. Journal of Neuroinflammation (2022) IF: 9.587
    Transient post-operative overexpression of CXCR2 on monocytes of traumatic brain injury patients drives monocyte chemotaxis toward cerebrospinal fluid and enhances monocyte-mediated immunogenic cell death of neurons in vitro

    DOI: 10.1186/s12974-022-02535-6

    PMID: 35768823

    		 Sample: cerebrospinal fluid (CSF),peripheral monocytes
  5. CANCER LETTERS (2022) IF: 8.679
    Decreased CXCR2 expression on circulating monocytes of colorectal cancer impairs recruitment and induces Re-education of tumor-associated macrophages

    DOI: 10.1016/j.canlet.2022.01.004

    PMID: 34999169

    		 Sample: serum,THP-1 cell,human circulating CD14+ monocytes
  6. JOURNAL OF HEADACHE AND PAIN (2021) IF: 7.277
    HMGB1, NLRP3, IL-6 and ACE2 levels are elevated in COVID-19 with headache: a window to the infection-related headache mechanism

    DOI: 10.1186/s10194-021-01306-7

    PMID: 34384355

    		 Sample: serum
  7. Antioxidants (2022) IF: 7.675
    Genipin Attenuates Diabetic Cognitive Impairment by Reducing Lipid Accumulation and Promoting Mitochondrial Fusion via FABP4/Mfn1 Signaling in Microglia

    DOI: 10.3390/antiox12010074
    Sample: HMC3 cells
  8. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208
    In Vitro Evaluation of Anti-Inflammatory and Protective Potential of an Extract from Cornus mas L. Fruit against H2O2-Induced Oxidative Stress in Human Skin Keratinocytes and Fibroblasts

    DOI: 10.3390/ijms232213755
  9. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2021) IF: 6.291
    miR-122–5p regulates hepatocytes damage caused by BaP and DBP co-exposure through SOCS1/STAT3 signaling in vitro

    DOI: 10.1016/j.ecoenv.2021.112570
    Sample: L02 cell
  10. Food & Function (2022) IF: 6.317
    Whole grain germinated brown rice regulates intestinal immune homeostasis and gastrointestinal hormones in type 2 diabetic patients—a randomized control trial

    DOI: 10.1039/D2FO00477A
    Sample: serum
  11. Oxidative Medicine and Cellular Longevity (2022) IF: 6.543
    Interleukin 10 Attenuates Angiotensin II-Induced Aortic Remodelling by Inhibiting Oxidative Stress-Induced Activation of the Vascular p38 and NF-κB Pathways

    DOI: 10.1155/2022/8244497
    Sample: plasma
  12. Oxidative Medicine and Cellular Longevity (2022) IF: 6.543
    DNA Methyltransferase 3b Accelerates the Process of Atherosclerosis

    DOI: 10.1155/2022/5249367

    PMID: 35422896

    		 Sample: Tregs
  13. Cancers (2023) IF: 6.575
    Salivary Interleukin Levels in Oral Squamous Cell Carcinoma and Oral Epithelial Dysplasia: Findings from a Sri Lankan Study

    DOI: 10.3390/cancers15051510
    Sample: Saliva
  14. Frontiers in Nutrition (2022) IF: 6.59
    Different oral and gut microbial profiles in those with Alzheimer's disease consuming anti-inflammatory diets.

    DOI: 10.3389/fnut.2022.974694
    Sample: serum
  15. Journal of Inflammation Research (2021) IF: 6.922
    Anti-Inflammatory Effects of Four Psilocybin-Containing Magic Mushroom Water Extracts in vitro on 15-Lipoxygenase Activity and on Lipopolysaccharide-Induced Cyclooxygenase-2 and Inflammatory Cytokines in Human U937 Macrophage Cells

    DOI: 10.2147/JIR.S317182
    Sample: U937 cell
  16. CELL PROLIFERATION (2019) IF: 5.039
    Inhibition of CREB‐mediated ZO‐1 and activation of NF‐κB‐induced IL‐6 by colonic epithelial MCT4 destroys intestinal barrier function

    DOI: 10.1111/cpr.12673
    Sample: CaCO2 cells，HT‐29 cell
  17. Frontiers in Chemistry (2022) IF: 5.221
    Exosomes Derived From Human Gingival Mesenchymal Stem Cells Attenuate the Inflammatory Response in Periodontal Ligament Stem Cells

    DOI: 10.3389/fchem.2022.863364

    PMID: 35464198

    		 Sample: GMSCs
  18. Food & Function (2022) IF: 5.396
    A randomised, double-blind, placebo-controlled trial of Bifidobacterium bifidum CCFM16 for manipulation of gut microbiota and relief from chronic constipation

    DOI: 10.1039/D1FO03896F
    Sample: serum
  19. WORLD JOURNAL OF GASTROENTEROLOGY (2016) IF: 5.742
    Inhibitory effect of miR-125b on hepatitis C virus core protein-induced TLR2/MyD88 signaling in THP-1 cells

    DOI: 10.3748/wjg.v22.i17.4354
    Sample: Cell culture supernatant
  20. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021) IF: 5.924
    ANXA1 Contained in EVs Regulates Macrophage Polarization in Tumor Microenvironment and Promotes Pancreatic Cancer Progression and Metastasis

    DOI: 10.3390/ijms222011018

    PMID: 34681678

    		 Sample: THP-1 cell
  21. Pediatric Obesity (2021) IF: 4
    The effects of Mediterranean diet on hepatic steatosis, oxidative stress, and inflammation in adolescents with non-alcoholic fatty liver disease: A randomized controlled trial

    DOI: 10.1111/ijpo.12872

    PMID: 34881510

    		 Sample: serum
  22. ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119
    LncRNA MEG3 ameliorates NiO nanoparticles-induced pulmonary inflammatory damage via suppressing the p38 mitogen activated protein kinases pathway

    DOI: 10.1002/tox.23464

    PMID: 35006638

    		 Sample: A549 cell
  23. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2021) IF: 4.223
    Occupational exposure of rural workers to pesticides in a vegetable-producing region in Brazil

    DOI: 10.1007/s11356-021-12444-5

    PMID: 33469792

    		 Sample: Plasma
  24. Scientific Reports (2017) IF: 4.259
    Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis

    DOI: 10.1038/s41598-017-14808-9
    Sample: tuberculous pleural effusion
  25. VIROLOGICA SINICA (2021) IF: 4.327
    Expansion of GARP-Expressing CD4+CD25−FoxP3+ T Cells and SATB1 Association with Activation and Coagulation in Immune Compromised HIV-1-Infected Individuals in South Africa

    DOI: 10.1007/s12250-021-00386-8
    Sample: Plasma
  26. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2020) IF: 4.352
    S-adenosyl-L-methionine (SAMe) halts the autoimmune response in patients with primary biliary cholangitis (PBC) via antioxidant and S-glutathionylation processes in cholangiocytes

    DOI: 10.1016/j.bbadis.2020.165895

    PMID: 32681864

    		 Sample: Serum
  27. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020) IF: 4.556
    Short-Term Physiological Effects of a Very Low-Calorie Ketogenic Diet: Effects on Adiponectin Levels and Inflammatory States

    DOI: 10.3390/ijms21093228
    Sample: serum
  28. Frontiers in Immunology (2019) IF: 4.716
    Severe Fever With Thrombocytopenia Syndrome Virus-Induced Macrophage Differentiation Is Regulated by miR-146

    DOI: 10.3389/fimmu.2019.01095
    Sample: serum
  29. Journal of Immunology Research (2021) IF: 4.818
    Remote Inflammatory Preconditioning Alleviates Lipopolysaccharide-Induced Acute Lung Injury via Inhibition of Intrinsic Apoptosis in Rats

    DOI: 10.1155/2021/1125199

    PMID: 34595242

    		 Sample: serum
  30. BIOCONJUGATE CHEMISTRY (2017) IF: 4.818
    Multifunctional Dextran Sulfate-Coated Reconstituted High Density Lipoproteins Target Macrophages and Promote Beneficial Antiatherosclerotic Mechanisms

    DOI: 10.1021/acs.bioconjchem.6b00600
    Sample: Cell culture supernatant
  31. Cells (2018) IF: 4.829
    Mesenchymal Stem Cells (MSCs) Coculture Protects [Ca2+]i Orchestrated Oxidant Mediated Damage in Differentiated Neurons In Vitro

    DOI: 10.3390/cells7120250
    Sample: Cell culture supernatant
  32. JOURNAL OF AFFECTIVE DISORDERS (2021) IF: 4.839
    In schizophrenia, immune-inflammatory pathways are strongly associated with depressive and anxiety symptoms, which are part of a latent trait which comprises neurocognitive impairments and schizophrenia symptoms.

    DOI: 10.1016/j.jad.2021.03.062
    Sample: Serum
  33. Biomolecules (2021) IF: 4.879
    Grape Pomace for Topical Application: Green NaDES Sustainable Extraction, Skin Permeation Studies, Antioxidant and Anti-Inflammatory Activities Characterization in 3D Human Keratinocytes

    DOI: 10.3390/biom11081181

    PMID: 34439847

    		 Sample: HaCaT keratinocytes
  34. MOLECULES (2022) IF: 4.927
    Modulatory Effect of Diosmin and Diosmetin on Metalloproteinase Activity and Inflammatory Mediators in Human Skin Fibroblasts Treated with Lipopolysaccharide

    DOI: 10.3390/molecules27134264

    PMID: 35807509

    		 Sample: human fibroblast cell
  35. Journal of Personalized Medicine (2022) IF: 4.945
    Pathway Phenotypes Underpinning Depression, Anxiety, and Chronic Fatigue Symptoms Due to Acute Rheumatoid Arthritis: A Precision Nomothetic Psychiatry Analysis

    DOI: 10.3390/jpm12030476
    Sample: Sera
  36. JOURNAL OF LEUKOCYTE BIOLOGY (2022) IF: 4.962
    Periodontal ligament stem cells promote polarization of M2 macrophages

    DOI: 10.1002/JLB.1MA1220-853RR

    PMID: 34982483

    		 Sample: THP-1 cell
  37. MOLECULAR IMMUNOLOGY (2019) IF: 3.064
    IL-16 regulates macrophage polarization as a target gene of mir-145-3p

    DOI: 10.1016/j.molimm.2018.12.027

    PMID: 30634164

    		 Sample: Cell lysate
  38. Diagnostics (2020) IF: 3.11
    The Endogenous Opioid System in Schizophrenia and Treatment Resistant Schizophrenia: Increased Plasma Endomorphin 2, and κ and μ Opioid Receptors Are Associated with Interleukin-6

    DOI: 10.3390/diagnostics10090633
    Sample: serum
  39. Oncology Letters (2022) IF: 3.111
    A role for serum cytokines and cell adhesion molecules in the non‑invasive diagnosis of colorectal cancer

    DOI: 10.3892/ol.2022.13443
    Sample: serum
  40. JOURNAL OF THE NEUROLOGICAL SCIENCES (2020) IF: 3.115
    Cytokine profile during pregnancy predicts relapses during pregnancy and postpartum in multiple sclerosis

    DOI: 10.1016/j.jns.2020.116811
    Sample: serum
  41. DIABETES RESEARCH AND CLINICAL PRACTICE (2019) IF: 3.239
    Effect of Ramadan diurnal fasting on visceral adiposity and serum adipokines in overweight and obese individuals

    DOI: 10.1016/j.diabres.2019.05.023

    PMID: 31150725

    		 Sample: Serum
  42. PLoS One (2022) IF: 3.24
    Clinical characteristics and outcomes of COVID-19 patients in Bali, Indonesia

    DOI: 10.1371/journal.pone.0269026

    PMID: 35687545

    		 Sample: serum
  43. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2020) IF: 3.245
    Trace element, immune and opioid biomarkers of unstable angina, increased atherogenicity and insulin resistance: Results of machine learning

    DOI: 10.1016/j.jtemb.2020.126703

    PMID: 33338984

    		 Sample: serum
  44. NEUROLOGICAL SCIENCES (2021) IF: 3.307
    Evaluation of IL-10, IFN-γ, and thiol–disulfide homeostasis in patients with drug-resistant epilepsy

    DOI: 10.1007/s10072-021-05331-x
    Sample: Serum
  45. BMC Pulmonary Medicine (2021) IF: 3.317
    Systemic and local cytokine profile and risk factors for persistent allergic airway inflammation in patients sensitised to house dust mite allergens

    DOI: 10.1186/s12890-021-01798-8

    PMID: 34930201

    		 Sample: serum,nasal lavage
  46. BMC Pulmonary Medicine (2021) IF: 3.317
    Role of IL-22 in persistent allergic airway diseases caused by house dust mite: a pilot study

    DOI: 10.1186/s12890-021-01410-z

    PMID: 33478443

    		 Sample: Serum,Nasal Lavage Fluid
  47. Diabetology & Metabolic Syndrome (2021) IF: 3.32
    The immune-opioid axis in prediabetes: predicting prediabetes with insulin resistance by plasma interleukin-10 and endomorphin-2 to kappa-opioid receptors ratio

    DOI: 10.1186/s13098-021-00677-w

    PMID: 34099024

    		 Sample: serum
  48. MOLECULAR AND CELLULAR BIOCHEMISTRY (2021) IF: 3.396
    Knockdown of RSAD2 attenuates B cell hyperactivity in patients with primary Sjögren’s syndrome (pSS) via suppressing NF-κb signaling pathway

    DOI: 10.1007/s11010-021-04070-z
    Sample: Cell culture supernatant(CD19+ B cells),Serum
  49. METABOLIC BRAIN DISEASE (2021) IF: 3.584
    In schizophrenia, non-remitters and partial remitters to treatment with antipsychotics are qualitatively distinct classes with respect to neurocognitive deficits and neuro-immune biomarkers: results of soft independent modeling of class analogy

    DOI: 10.1007/s11011-021-00685-9

    PMID: 33580860

    		 Sample: Plasma
  50. TUMOR BIOLOGY (2017) IF: 3.65
    PKCζ in prostate cancer cells represses the recruitment and M2 polarization of macrophages in the prostate cancer microenvironment:

    DOI: 10.1177/1010428317701442
    Sample: Cell culture supernatant,Cell lysate
  51. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2022) IF: 3.657
    Can the Prognosis of COVID-19 Disease Be Determined by Fecal Markers and Cytokines?

    DOI: 10.1089/jir.2022.0098

    PMID: 36179036

    		 Sample: fecal
  52. Infectious Agents and Cancer (2023) IF: 3.698
    Inhibitory effect and mechanism of Lactobacillus crispatus on cervical precancerous cells Ect1/E6E7 and screening of early warning factors

    DOI: 10.1186/s13027-023-00483-1
    Sample: Ect1/E6E7 cell
  53. PLoS One (2022) IF: 3.752
    Exploring alternative cytokines as potential biomarkers for latent tuberculosis infection in pregnant women

    DOI: 10.1371/journal.pone.0270552

    PMID: 35802700

    		 Sample: plasma
  54. CNS SPECTRUMS (2021) IF: 3.79
    A pathway phenotype linking metabolic, immune, oxidative, and opioid pathways with comorbid depression, atherosclerosis, and unstable angina

    DOI: 10.1017/S1092852921000432

    PMID: 34039448

    		 Sample: Serum
  55. Biology-Basel (2020) IF: 3.796
    Induction of CD4+CD25+ Regulatory T Cells from In Vitro Grown Human Mononuclear Cells by Sparteine Sulfate and Harpagoside

    DOI: 10.3390/biology9080211
    Sample: Cell culture supernatant
  56. JOURNAL OF AFFECTIVE DISORDERS (2020) IF: 3.892
    Construction of an exposure-pathway-phenotype in children with depression due to transfusion-dependent thalassemia: Results of (un)supervised machine learning.

    DOI: 10.1016/j.jad.2020.12.089
    Sample: Serum
  57. RESPIRATORY RESEARCH (2020) IF: 3.924
    Thymosin β10 promotes tumor-associated macrophages M2 conversion and proliferation via the PI3K/Akt pathway in lung adenocarcinoma

    DOI: 10.1186/s12931-020-01587-7
    Sample: THP-1 cell
  58. Annals of Translational Medicine (2022) IF: 3.932
    Possible causes of atherosclerosis: lncRNA COLCA1 induces oxidative stress in human coronary artery endothelial cells and impairs wound healing

    DOI: 10.21037/atm-22-507
    Sample: HCAECs
  59. Annals of Translational Medicine (2021) IF: 3.932
    A simple lectin-based biochip might display the potential clinical value of glycomics in patients with spontaneous intracerebral hemorrhage

    DOI: 10.21037/atm-20-7315

    PMID: 33987242

    		 Sample: serum
  60. PLoS Neglected Tropical Diseases (2016) IF: 3.948
    Clonorchis sinensis Co-infection Could Affect the Disease State and Treatment Response of HBV Patients

    DOI: 10.1371/journal.pntd.0004806
    Sample: Serum,Cell culture supernatant
  61. NEUROGASTROENTEROLOGY AND MOTILITY (2022) IF: 3.96
    Somatization is associated with altered serum levels of vitamin D, serotonin, and brain-derived neurotrophic factor in patients with predominant diarrhea irritable bowel syndrome

    DOI: 10.1111/nmo.14512
    Sample: serum
  62. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2019) IF: 2.086
    In vitro impact of bisphenol A on maturation and function of monocyte-derived dendritic cells in patients with primary Sjögren’s syndrome

    DOI: 10.1080/08923973.2019.1706554
    Sample: PBMCs
  63. Sleep and Breathing (2020) IF: 2.162
    Intermittent hypoxia induces tumor immune escape in murine S180 solid tumors via the upregulation of TGF-β 1 in mice

    DOI: 10.1007/s11325-020-02166-2

    PMID: 32840731

    		 Sample: Tissue homogenate
  64. Biomed Research International (2020) IF: 2.276
    Blood Monocyte Phenotype Fingerprint of Stable Coronary Artery Disease: A Cross-Sectional Substudy of SMARTool Clinical Trial

    DOI: 10.1155/2020/8748934
    Sample: serum
  65. BMC Cardiovascular Disorders (2022) IF: 2.298
    The abnormal distribution of peripheral B1 cells and transition B cells in patients with idiopathic dilated cardiomyopathy: a pilot study

    DOI: 10.1186/s12872-022-02461-8

    PMID: 35246021

    		 Sample: plasma
  66. JOURNAL OF MEDICAL VIROLOGY (2021) IF: 2.327
    Analysis of serum cytokine and protective vitamin D levels in severe cases of COVID-19

    DOI: 10.1002/jmv.27294

    PMID: 34427934

    		 Sample: serum
  67. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2020) IF: 2.352
    A case of asthma with Behcet’s disease: successful treatment with omalizumab and its effects on recurrent aphthous lesions

    DOI: 10.1080/08923973.2020.1789656
    Sample: Serum
  68. CLINICAL RHEUMATOLOGY (2020) IF: 2.394
    The clinical value of interleukins-8, -10, and -17 in idiopathic granulomatous mastitis

    DOI: 10.1007/s10067-020-04925-8
    Sample: blood
  69. Experimental and Therapeutic Medicine (2021) IF: 2.447
    Mangiferin inhibits hypoxia/reoxygenation‑induced alveolar epithelial cell injury via the SIRT1/AMPK signaling pathway

    DOI: 10.3892/etm.2021.10654
    Sample: A549 cell
  70. Experimental and Therapeutic Medicine (2020) IF: 2.447
    Increased expression of IFN‑γ in preeclampsia impairs human trophoblast invasion via a SOCS1/JAK/STAT1 feedback loop

    DOI: 10.3892/etm.2020.9544
    Sample: Tissue homogenate
  71. American Journal of Rhinology & Allergy (2021) IF: 2.467
    Immunosuppressive Regulation of Dendritic Cells and T Cells in Allergic Rhinitis by Semaphorin 3A:

    DOI: 10.1177/19458924211005592
    Sample: Cell
  72. ACTA TROPICA (2018) IF: 2.509
    Assessment of chemokine and cytokine signatures in patients with dengue infection: A hospital-based study in Kolkata, India

    DOI: 10.1016/j.actatropica.2018.10.017

    PMID: 30395811

    		 Sample: Serum
  73. Clinical Respiratory Journal (2021) IF: 2.57
    Adhesion molecules as diagnostic and severity biomarkers in pediatric community-acquired pneumonia

    DOI: 10.1111/crj.13334

    PMID: 33484111

    		 Sample: Whole Blood,Serum
  74. MICROBIAL PATHOGENESIS (2019) IF: 2.581
    Isolation, characterization and analysis of pro-inflammatory potential of Klebsiella pneumoniae outer membrane vesicles

    DOI: 10.1016/j.micpath.2019.103719

    PMID: 31493501

    		 Sample: Cell culture supernatant
  75. Evidence-based Complementary and Alternative Medicine (2022) IF: 2.65
    Effect of Thymosin on Inflammatory Factor Levels, Immune Function, and Quality of Life in Lung Cancer Patients Undergoing Radical Thoracoscopic Surgery

    DOI: 10.1155/2022/8749999

    PMID: 35832513

    		 Sample: Serum
  76. METABOLIC BRAIN DISEASE (2020) IF: 2.726
    Chronic fatigue syndrome and fibromyalgia-like symptoms are an integral component of the phenome of schizophrenia: neuro-immune and opioid system correlates

    DOI: 10.1007/s11011-020-00619-x

    PMID: 32965599

    		 Sample: Serum
  77. BIOMEDICAL AND ENVIRONMENTAL SCIENCES (2022) IF: 2.831
    Periodontal Ligament Stem Cells Reverse the High Glucose Level-Induced Inflammatory State of Macrophages

    DOI: 10.3967/bes2022.089

    PMID: 35945185

    		 Sample: THP-1 cell
  78. BMC Complementary Medicine and Therapies (2023) IF: 2.838
    Exploration of the mechanism by which Huangqi Guizhi Wuwu decoction inhibits Lps-induced inflammation by regulating macrophage polarization based on network pharmacology

    DOI: 10.1186/s12906-022-03826-4
    Sample: human histiocytic lymphoma (U-937) cell
  79. CLINICAL RHEUMATOLOGY (2022) IF: 2.98
    Interleukin-35 promotes Breg expansion and interleukin-10 production in CD19+ B cells in patients with ankylosing spondylitis

    DOI: 10.1007/s10067-022-06137-8

    PMID: 35420296

    		 Sample: serum
  80. NEUROTOXICITY RESEARCH (2020) IF: 2.992
    Major Depression in Children with Transfusion-Dependent Thalassemia Is Strongly Associated with the Combined Effects of Blood Transfusion Rate, Iron Overload, and Increased Pro-inflammatory Cytokines

    DOI: 10.1007/s12640-020-00193-1

    PMID: 32335809

    		 Sample: Serum
  81. Genetic Testing and Molecular Biomarkers (2019) IF: 1.121
    Association of High Mobility Group Box Protein B1 Gene Polymorphisms with Pneumonia Susceptibility and Severity

    DOI: 10.1089/gtmb.2018.0174

    PMID: 30562142

    		 Sample: Plasma
  82. Experimental and Therapeutic Medicine (2019) IF: 1.448
    Short‑term efficacy and safety of prednisone in herpes zoster and the effects on IL‑6 and IL‑10

    DOI: 10.3892/etm.2019.7898
    Sample: serum
  83. MEDICINE (2020) IF: 1.552
    Regulatory role and mechanism of the inhibition of the Mcl-1 pathway during apoptosis and polarization of H37Rv-infected macrophages

    DOI: 10.1097/MD.0000000000022438

    PMID: 33080678

    		 Sample: Cell culture supernatant
  84. BMC Anesthesiology (2019) IF: 1.619
    A comparison of effects of scalp nerve block and local anesthetic infiltration on inflammatory response, hemodynamic response, and postoperative pain in patients undergoing craniotomy for cerebral aneurysms: a randomized controlled trial

    DOI: 10.1186/s12871-019-0760-4
    Sample: plasm
  85. Experimental and Therapeutic Medicine (2020) IF: 1.785
    Systematically transplanted human gingiva‑derived mesenchymal stem cells regulate lipid metabolism and inflammation in hyperlipidemic mice with periodontitis

    DOI: 10.3892/etm.2019.8256
    Sample: Serum
  86. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2015) IF: 1.859
    Decreased monocyte subsets and TLR4-mediated functions in patients with acute severe fever with thrombocytopenia syndrome (SFTS)

    DOI: 10.1016/j.ijid.2015.12.009
    Sample: Cell culture supernatant
  87. Evidence-based Complementary and Alternative Medicine (2019) IF: 1.984
    In Vitro Immunomodulatory Effect of Food Supplement from Aloe vera

    DOI: 10.1155/2019/5961742

    PMID: 30941196

    		 Sample: Cell culture supernatant
  88. Medical Science Monitor Basic Research (2022)
    Production of Inflammatory Mediators in Conditioned Medium of Adipose Tissue-Derived Mesenchymal Stem Cells (ATMSC)-Treated Fresh Frozen Plasma

    DOI: 10.12659/MSMBR.933726
    Sample: Adipose Tissue-Derived Mesenchymal Stem Cells (ATM
  89. Romanian Journal of Internal Medicine (2021)
    Interleukin-10 (IL-10) 1082 promoter polymorphisms and plasma IL-10 levels in patients with bacterial sepsis

    DOI: 10.2478/rjim-2020-0033
    Sample: plasma
  90. ACTA CLINICA BELGICA (2019) IF: 0.96
    Interleukin 8 as predictive factor for response to chemotherapy in colorectal cancer patients

    DOI: 10.1080/17843286.2019.1680133
    Sample: serum
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