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Mouse TNF-α(Tumor Necrosis Factor Alpha) ELISA Kit

Cat.No.:E-EL-M3063
Reactivity: Mouse

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96T
48T
24T
96T*5
96T*10

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Product Details

Properties

Assay type	Sandwich-ELISA
Format	96T/48T
Assay time	3.5h
Detection range	7.81-500 pg/mL
Sensitivity	4.69 pg/mL
Sample type &Sample volume	serum, plasma and other biological fluids; 100μL
Specificity	This kit recognizes Mouse TNF-α in samples. No significant cross-reactivity or interference between Mouse TNF-α and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are < 10%.
Application	This ELISA kit applies to the in vitro quantitative determination of Mouse TNF-α concentrations in serum, plasma and other biological fluids.

Test Principle

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse TNF-α. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Mouse TNF-α and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse TNF-α, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Mouse TNF-α. You can calculate the concentration of Mouse TNF-α in the samples by comparing the OD of the samples to the standard curve.

Kit components & Storage

An unopened kit can be stored at 2-8℃ for 1 month. If the kit is not supposed to be used within 1 month, store the components separately according to the following conditions once the kit is received.

Item	Specifications	Storage
Micro ELISA Plate(Dismountable)	96T: 8 wells ×12 strips 48T: 8 wells ×6 strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 48T: 1 vial, 60 μL
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 48T: 1 vial, 60 μL	-20℃(Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL
HRP Conjugate Diluent	1 vial, 14 mL
Concentrated Wash Buffer (25×)	1 vial, 30 mL
Substrate Reagent	1 vial, 10 mL	2-8℃(Protect from light)
Stop Solution	1 vial, 10 mL	2-8°C
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

Technical Data

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Mouse TNF-α were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Mouse TNF-α were tested on 3 different plates, 20 replicates in each plate.

	Intra-assay Precision			Inter-assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	20	20	20
Mean (pg/mL)	23.99	59.60	188.68	25.90	59.84	172.83
Standard deviation	1.42	3.47	6.40	1.68	2.46	7.50
CV (%)	5.93	5.82	3.39	6.50	4.11	4.34

Recovery

The recovery of Mouse TNF-α spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type	Range (%)	Average Recovery (%)
Serum(n=8)	95-112	102
EDTA plasma (n=8)	94-112	102
Cell culture media (n=8)	93-107	100

Linearity

Samples were spiked with high concentrations of Mouse TNF-α and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

Target Information

Synonyms	DIF, TNF-alpha, TNFA,TNFSF2,TNF,TNFa
Research Area	Cancer, Cardiovascular, Metabolism, Immunology, Signal transduction

Assay Procedures

	1. Add 100μL standard or sample to the wells. Incubate for 90 min at 37°C
	2. Discard the liquid, immediately add 100μL Biotinylated Detection Ab working solution to each well. Incubate for 60 min at 37°C
	3. Aspirate and wash the plate for 3 times
	4. Add 100μL HRP conjugate working solution. Incubate for 30 min at 37°C. Aspirate and wash the plate for 5 times
	5. Add 90μL Substrate Reagent. Incubate for 15 min at 37°C
	6. Add 50μL Stop Solution
	7. Read the plate at 450nm immediately. Calculation of the results

Citations

NATURE CELL BIOLOGY (2022) IF: 28.824
Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses

DOI: 10.1038/s41556-022-00853-8

PMID: 35256775
Sample: serum
BRAIN BEHAVIOR AND IMMUNITY (2022) IF: 19.227
Intestinal dysbiosis mediates cognitive impairment via the intestine and brain NLRP3 inflammasome activation in chronic sleep deprivation

DOI: 10.1016/j.bbi.2022.11.013

PMID: 36427810
Sample: serum
ACS Central Science (2023) IF: 18.728
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury

DOI: 10.1021/acscentsci.2c01424

PMID: 36968547
Sample: bronchoalveolar lavage fluid (BALF),lung
Science Translational Medicine (2020) IF: 16.304
Combination of metabolic intervention and T cell therapy enhances solid tumor immunotherapy

DOI: 10.1126/scitranslmed.aaz6667

PMID: 33239389
Sample: Cell culture supernatant
CHEMICAL ENGINEERING JOURNAL (2022) IF: 16.744
Tumor microenvironment activated nanoreactors for chemiluminescence imaging-guided simultaneous elimination of breast tumors and tumor-resident intracellular pathogens

DOI: 10.1016/j.cej.2022.139939

Sample: serum
CHEMICAL ENGINEERING JOURNAL (2022) IF: 16.744
Lyophilization-inactivated cancer cells composited Janus scaffold for tumor postoperative immuno-chemotherapy

DOI: 10.1016/j.cej.2022.140619

Sample: Bone marrow-derived dendritic cell (BMDC)
CHEMICAL ENGINEERING JOURNAL (2022) IF: 16.744
Enzyme-induced morphological transformation of self-assembled peptide nanovehicles potentiates intratumoral aggregation and inhibits tumour immunosuppression

DOI: 10.1016/j.cej.2022.140466

Sample: serum
Advanced Science (2022) IF: 16.806
RNF115 Inhibits the Post-ER Trafficking of TLRs and TLRs-Mediated Immune Responses by Catalyzing K11-Linked Ubiquitination of RAB1A and RAB13

DOI: 10.1002/advs.202105391

PMID: 35343654
Sample: sera
ADVANCED FUNCTIONAL MATERIALS (2020) IF: 16.836
Quantitative Photoacoustic Diagnosis and Precise Treatment of Inflammation In Vivo Using Activatable Theranostic Nanoprobe

DOI: 10.1002/adfm.202001771

Sample: Serum
Small (2023) IF: 15.153
Oral Metal-Free Melanin Nanozymes for Natural and Durable Targeted Treatment of Inflammatory Bowel Disease (IBD)

DOI: 10.1002/smll.202207350

Sample: colon tissue
Small (2022) IF: 15.153
Kidney-Targeted Nanoparticles Loaded with the Natural Antioxidant Rosmarinic Acid for Acute Kidney Injury Treatment

DOI: 10.1002/smll.202204388

PMID: 36253133
Sample: kidney
BIOMATERIALS (2022) IF: 15.304
Blood-brain barrier Permeable nanoparticles for Alzheimer's disease treatment by selective mitophagy of microglia

DOI: 10.1016/j.biomaterials.2022.121690

PMID: 35965114
Sample: Brain tissue
Bioactive Materials (2021) IF: 14.593
Secretions from hypochlorous acid-treated tumor cells delivered in a melittin hydrogel potentiate cancer immunotherapy

DOI: 10.1016/j.bioactmat.2021.07.019

PMID: 34820587
Sample: B16–F10 cells,Red blood cells
Bioactive Materials (2021) IF: 14.593
An antioxidant system through conjugating superoxide dismutase onto metal-organic framework for cardiac repair

DOI: 10.1016/j.bioactmat.2021.08.019

Sample: serum
Acta Pharmaceutica Sinica B (2022) IF: 14.903
Reprogrammed siTNFα/neutrophil cytopharmaceuticals targeting inflamed joints for rheumatoid arthritis therapy

DOI: 10.1016/j.apsb.2022.08.012

Sample: bone marrow neutrophil
Acta Pharmaceutica Sinica B (2023) IF: 14.903
Berberine improves central memory formation of CD8+ T cells: Implications for design of natural product-based vaccines

DOI: 10.1016/j.apsb.2023.02.017

Sample: Lymphocytes
Science Advances (2022) IF: 14.957
Glucocorticoid-induced loss of beneficial gut bacterial extracellular vesicles is associated with the pathogenesis of osteonecrosis

DOI: 10.1126/sciadv.abg8335

Sample: serum
CHEMICAL ENGINEERING JOURNAL (2022) IF: 13.273
2D MoSe2@PVP nanosheets with multi-enzyme activity alleviate the acute pancreatitis via scavenging the reactive oxygen and nitrogen species

DOI: 10.1016/j.cej.2022.136792

Sample: serum
JOURNAL OF PINEAL RESEARCH (2023) IF: 12.081
Melatonin inhibits atherosclerosis progression via Galectin-3 downregulation to enhance autophagy and inhibit inflammation

DOI: 10.1111/jpi.12855

Sample: serum
Bone Research (2018) IF: 12.354
Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines

DOI: 10.1038/s41413-018-0012-0

Sample: Serum
Journal for ImmunoTherapy of Cancer (2023) IF: 12.469
Novel combination strategy of high intensity focused ultrasound (HIFU) and checkpoint blockade boosted by bioinspired and oxygen-supplied nanoprobe for multimodal imaging-guided cancer therapy

DOI: 10.1136/jitc-2022-006226

Sample: Serum
Journal for ImmunoTherapy of Cancer (2022) IF: 12.469
Nanoparticle delivery of miR-21-3p sensitizes melanoma to anti-PD-1 immunotherapy by promoting ferroptosis

DOI: 10.1136/jitc-2021-004381

PMID: 35738798
Sample: B16F10 cell-xenograft
Advanced Healthcare Materials (2022) IF: 11.092
Switchable ROS Scavenger/Generator for MRI-Guided Anti-Inflammation and Anti-Tumor Therapy with Enhanced Therapeutic Efficacy and Reduced Side Effects

DOI: 10.1002/adhm.202202043

Sample: serum
JOURNAL OF CONTROLLED RELEASE (2022) IF: 11.467
Nano-sponge-like liposomes remove cholesterol crystals for antiatherosclerosis

DOI: 10.1016/j.jconrel.2022.07.021

PMID: 35870569
Sample: serum
JOURNAL OF CONTROLLED RELEASE (2023) IF: 11.467
Brain-neuron targeted nanoparticles for peptide synergy therapy at dual-target of Alzheimer's disease

DOI: 10.1016/j.jconrel.2023.01.074

Sample: brain tissues
Theranostics (2022) IF: 11.556
Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy

DOI: 10.7150/thno.68667

PMID: 35547755
Sample: blood
Redox Biology (2022) IF: 11.799
STING signaling sensing of DRP1-dependent mtDNA release in kupffer cells contributes to lipopolysaccharide-induced liver injury in mice

DOI: 10.1016/j.redox.2022.102367

PMID: 35724543
Sample: serum,Kupffer cell (KCs)
Nano Research (2022) IF: 10.269
Whisker of biphasic calcium phosphate ceramics: Osteo-immunomodulatory behaviors

DOI: 10.1007/s12274-022-4591-0

Sample: RAw 264.7 cell
ACS Applied Materials & Interfaces (2022) IF: 10.383
Self-Activated Cascade Biocatalysis of Glucose Oxidase–Polycation–Iron Nanoconjugates Augments Cancer Immunotherapy

DOI: 10.1021/acsami.2c04894

Sample: serum
ACS Applied Materials & Interfaces (2022) IF: 10.383
In Situ Growth of Tunable Gold Nanoparticles by Titania Nanotubes Templated Electrodeposition for Improving Osteogenesis through Modulating Macrophages Polarization

DOI: 10.1021/acsami.2c13976
JOURNAL OF NANOBIOTECHNOLOGY (2022) IF: 10.435
Intracellular marriage of bicarbonate and Mn ions as “immune ion reactors” to regulate redox homeostasis and enhanced antitumor immune responses

DOI: 10.1186/s12951-022-01404-x

Sample: serum
JOURNAL OF NANOBIOTECHNOLOGY (2021) IF: 10.435
Gold nanoparticles reduce inflammation in cerebral microvessels of mice with sepsis

DOI: 10.1186/s12951-021-00796-6

PMID: 33608025
Sample: Tissue（brain）
JOURNAL OF NANOBIOTECHNOLOGY (2022) IF: 10.435
Biomimetic nanoprobe-augmented triple therapy with photothermal, sonodynamic and checkpoint blockade inhibits tumor growth and metastasis

DOI: 10.1186/s12951-022-01287-y

PMID: 35168608
Sample: tumor cell
Acta Biomaterialia (2023) IF: 10.633
Targeted therapy for peri-prosthetic osteolysis using macrophage membrane-encapsulated human urine-derived stem cell extracellular vesicles

DOI: 10.1016/j.actbio.2023.02.003

Sample: RAW264.7 cell,osteoclasto
Bioengineering & Translational Medicine (2022) IF: 10.711
Baicalein self-microemulsion based on drug–phospholipid complex for the alleviation of cytokine storm

DOI: 10.1002/btm2.10357

Sample: plasma
CARBOHYDRATE POLYMERS (2022) IF: 10.723
Aloe polymeric acemannan inhibits the cytokine storm in mouse pneumonia models by modulating macrophage metabolism

DOI: 10.1016/j.carbpol.2022.120032

PMID: 36184177
Sample: bronchoalveolar fluid,RAW264.7 cell
SCIENCE OF THE TOTAL ENVIRONMENT (2023) IF: 10.753
The role of reactive astrocytes in neurotoxicity induced by ultrafine particulate matter

DOI: 10.1016/j.scitotenv.2023.161416

Sample: mixed glial cell
SCIENCE OF THE TOTAL ENVIRONMENT (2022) IF: 10.753
Aerofloral studies and allergenicity of dominant pollen types in Taraba and Bauchi States of Northeastern Nigeria

DOI: 10.1016/j.scitotenv.2022.157076

PMID: 35780899
Sample: plasma
Materials Today Bio (2023) IF: 10.761
Treg-targeted efficient-inducible platform for collagen-induced arthritis treatment

DOI: 10.1016/j.mtbio.2023.100557

Sample: serum
Nano-Micro Letters (2019) IF: 9.0429
Inorganic Nanozyme with Combined Self-Oxygenation/Degradable Capabilities for Sensitized Cancer Immunochemotherapy

DOI: 10.1007/s40820-019-0305-x

Sample: Serum
ACS Applied Materials & Interfaces (2022) IF: 9.2289
Bioactive Injectable Hydrogel Dressings for Bacteria-Infected Diabetic Wound Healing: A “Pull–Push” Approach

DOI: 10.1021/acsami.2c04300

Sample: regenerated wound samples
CARBOHYDRATE POLYMERS (2019) IF: 9.381
Galactan isolated from Cantharellus cibarius modulates antitumor immune response by converting tumor-associated macrophages toward M1-like phenotype

DOI: 10.1016/j.carbpol.2019.115295

PMID: 31582086
Sample: Cell culture supernatant
CARBOHYDRATE POLYMERS (2021) IF: 9.381
Dissolvable microneedles based on Panax notoginseng polysaccharide for transdermal drug delivery and skin dendritic cell activation

DOI: 10.1016/j.carbpol.2021.118211

PMID: 34127215
Sample: Tissue Slice
JOURNAL OF NANOBIOTECHNOLOGY (2023) IF: 9.429
Melanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy

DOI: 10.1186/s12951-023-01807-4

Sample: serum
BRITISH JOURNAL OF PHARMACOLOGY (2023) IF: 9.4730
Microsomal prostaglandin E synthase-1 inhibition prevents adverse cardiac remodeling after myocardial infarction in mice

DOI: 10.1111/bph.16061

Sample: Plasma
Small (2018) IF: 9.5980
Neoadjuvant Chemotherapy Based on Abraxane/Human Neutrophils Cytopharmaceuticals with Radiotherapy for Gastric Cancer

DOI: 10.1002/smll.201804191

PMID: 30549431
Sample: Serum,Tissue homogenate
ENVIRONMENTAL POLLUTION (2022) IF: 9.988
Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line

DOI: 10.1016/j.envpol.2022.120217

PMID: 36155221
Sample: hippocampi
ANALYTICAL CHEMISTRY (2022) IF: 8.0079
Visual Identification of Trichosporon asahii, a Gut Yeast Associated with Obesity, Using an Enzymatic NIR Fluorescent Probe

DOI: 10.1021/acs.analchem.2c01691

PMID: 35920602
Sample: hepatic tissue,epididymal fat tissue
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 8.025
Structural characterization of a soluble polysaccharide SSPS1 from soy whey and its immunoregulatory activity in macrophages

DOI: 10.1016/j.ijbiomac.2022.07.043

PMID: 35835298
Sample: Raw 264.7 macrophages
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 8.025
A glycoprotein from mountain cultivated ginseng: Insights into their chemical characteristics and intracellular antioxidant activity

DOI: 10.1016/j.ijbiomac.2022.07.023

PMID: 35817242
Sample: RAW264.7 cell
Journal of Neuroinflammation (2021) IF: 8.3219
Sirtuin 3 protects against anesthesia/surgery-induced cognitive decline in aged mice by suppressing hippocampal neuroinflammation

DOI: 10.1186/s12974-021-02089-z

PMID: 33541361
Sample: Tissue homogenate(Hippocampal homogenate)
Cell Death & Disease (2022) IF: 8.4689
Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32

DOI: 10.1038/s41419-022-04962-y

PMID: 35739102
Sample: RAW264.7 cell
Theranostics (2020) IF: 8.5790
Engineering blood exosomes for tumor-targeting efficient gene/chemo combination therapy

DOI: 10.7150/thno.45028

PMID: 32685027
Sample: Serum
EXPERIMENTAL AND MOLECULAR MEDICINE (2022) IF: 8.718
Identification of novel rheumatoid arthritis-associated MiRNA-204-5p from plasma exosomes

DOI: 10.1038/s12276-022-00751-x

PMID: 35354913
Sample: Serum
Cellular and Molecular Gastroenterology and Hepatology (2022) IF: 8.7970
Klebsiella pneumoniae induces inflammatory bowel disease through caspase-11-mediated IL-18 in the gut epithelial cells

DOI: 10.1016/j.jcmgh.2022.11.005

Sample: colon tissue
CHEMOSPHERE (2022) IF: 8.943
Oral administration of Bacillus cereus GW-01 alleviates the accumulation and detrimental effects of β-cypermethrin in mice

DOI: 10.1016/j.chemosphere.2022.137333

Sample: serum
International Journal of Nanomedicine (2022) IF: 7.033
Biocompatible Assessment of Erythrocyte Membrane-Camouflaged Polymeric PLGA Nanoparticles in Pregnant Mice: Both on Maternal and Fetal/Juvenile Mice

DOI: 10.2147/IJN.S384906

Sample: serum
CNS Neuroscience & Therapeutics (2023) IF: 7.035
Dl-3-n-butylphthalide promotes synaptic plasticity by activating the Akt/ERK signaling pathway and reduces the blood–brain barrier leakage by inhibiting the HIF-1α/MMP signaling pathway in vascular dementia model mice

DOI: 10.1111/cns.14112

Sample: brain tissue
FOOD HYDROCOLLOIDS (2020) IF: 7.053
Generation of structurally diverse pectin oligosaccharides having prebiotic attributes

DOI: 10.1016/j.foodhyd.2020.105988

Sample: RAW 264.7 cell
CHEMOSPHERE (2020) IF: 7.086
Interleukin 17A deficiency alleviates fluoride-induced testicular injury by inhibiting the immune response and apoptosis

DOI: 10.1016/j.chemosphere.2020.128178

Sample: interstitial fluid
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022) IF: 7.088
Discovery of novel hybrids containing clioquinol−1-benzyl-1,2,3,6-tetrahydropyridine as multi-target-directed ligands (MTDLs) against Alzheimer's disease

DOI: 10.1016/j.ejmech.2022.114841

Sample: cortex
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022) IF: 7.088
Discovery of fusidic acid derivatives as novel STING inhibitors for treatment of sepsis

DOI: 10.1016/j.ejmech.2022.114814

PMID: 36228412
Sample: RAW264.7 cells
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022) IF: 7.088
Design and synthesis of hederagenin derivatives modulating STING/NF-κB signaling for the relief of acute liver injury in septic mice

DOI: 10.1016/j.ejmech.2022.114911
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2023) IF: 7.129
Acute liver injury induced by carbon tetrachloride reversal by Gandankang aqueous extracts through nuclear factor erythroid 2-related factor 2 signaling pathway

DOI: 10.1016/j.ecoenv.2023.114527

Sample: liver,serum
ACTA PHARMACOLOGICA SINICA (2023) IF: 7.169
Bavachin protects against diet-induced hepatic steatosis and obesity in mice

DOI: 10.1038/s41401-023-01056-z

Sample: Serum
CARBOHYDRATE POLYMERS (2020) IF: 7.182
Chitosan oligosaccharides attenuate loperamide-induced constipation through regulation of gut microbiota in mice

DOI: 10.1016/j.carbpol.2020.117218

PMID: 33278982
Sample: Tissue homogenate
Acta Biomaterialia (2020) IF: 7.242
Near-infrared/pH dual-responsive nanocomplexes for targeted imaging and chemo/gene/photothermal tri-therapies of non-small cell lung cancer

DOI: 10.1016/j.actbio.2020.03.004

PMID: 32151700
Sample: Whole Blood
Oxidative Medicine and Cellular Longevity (2023) IF: 7.31
RRP Regulates Autophagy through the AMPK Pathway to Alleviate the Effect of Cell Senescence on Atherosclerosis

DOI: 10.1155/2023/9645789

Sample: serum
Oxidative Medicine and Cellular Longevity (2023) IF: 7.31
Combination Therapy with Indigo and Indirubin for Ulcerative Colitis via Reinforcing Intestinal Barrier Function

DOI: 10.1155/2023/2894695

Sample: colonic tissue
FREE RADICAL BIOLOGY AND MEDICINE (2022) IF: 7.376
Inhibition of neuronal nitric oxide synthase protects against hippocampal neuronal injuries by increasing neuropeptide Y expression in temporal lobe epilepsy mice

DOI: 10.1016/j.freeradbiomed.2022.06.221

PMID: 35714846
Sample: hippocampal tissue
FREE RADICAL BIOLOGY AND MEDICINE (2021) IF: 7.376
ADAM10 suppresses demyelination and reduces seizure susceptibility in cuprizone-induced demyelination model

DOI: 10.1016/j.freeradbiomed.2021.05.001

PMID: 33965566
Sample: Tissue homogenate
BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 7.419
Xiaojianzhong decoction attenuates gastric mucosal injury by activating the p62/Keap1/Nrf2 signaling pathway to inhibit ferroptosis

DOI: 10.1016/j.biopha.2022.113631

PMID: 36122518
Sample: gastric mucosal tissue,
BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 7.419
Study on a novel enzymatic colon-targeted particle of total saponins of Pulsatilla by mechanical grinding technology in a solvent free system

DOI: 10.1016/j.biopha.2022.113645

PMID: 36115109
Sample: serum
BIOMEDICINE & PHARMACOTHERAPY (2023) IF: 7.419
Phillygenin inhibited M1 macrophage polarization and reduced hepatic stellate cell activation by inhibiting macrophage exosomal miR-125b-5p

DOI: 10.1016/j.biopha.2023.114264

Sample: RAW264.7 cell
BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 7.419
Lack of Nogo-B expression ameliorates PPARγ deficiency-aggravated liver fibrosis by regulating TLR4-NF-κB-TNF-α axis and macrophage polarization

DOI: 10.1016/j.biopha.2022.113444

PMID: 36076559
Sample: serum
BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 7.419
1-Deoxynojirimycin attenuates septic cardiomyopathy by regulating oxidative stress, apoptosis, and inflammation via the JAK2/STAT6 signaling pathway

DOI: 10.1016/j.biopha.2022.113648

PMID: 36108388
Sample: serum
FOOD RESEARCH INTERNATIONAL (2022) IF: 7.425
Physicochemical characteristics and biological activities of soluble dietary fibers isolated from the leaves of different quinoa cultivars

DOI: 10.1016/j.foodres.2022.112166
FOOD CHEMISTRY (2021) IF: 7.514
Premna microphylla Turcz leaf pectin exhibited antioxidant and anti-inflammatory activities in LPS-stimulated RAW 264.7 macrophages

DOI: 10.1016/j.foodchem.2021.129164

PMID: 33550022
Sample: Cell culture medium
Frontiers in Immunology (2022) IF: 7.561
PHLDA1 Suppresses TLR4-Triggered Proinflammatory Cytokine Production by Interaction With Tollip

DOI: 10.3389/fimmu.2022.731500

Sample: RAW264.7 cell,Bone marrow-derived macrophages
Journal of Materials Chemistry B (2022) IF: 7.571
Oxidized chondroitin sulfate eye drops ameliorate the prognosis of fungal keratitis with anti-inflammatory and antifungal effects

DOI: 10.1039/D2TB00114D

PMID: 36070420
Sample: corneas
Biomaterials Science (2022) IF: 7.59
Single-component lipid nanoparticles for engineering SOCS1 gene-silenced dendritic cells to boost tumor immunotherapy

DOI: 10.1039/D2BM01549H

Sample: serum
Antioxidants (2022) IF: 7.675
Genipin Attenuates Diabetic Cognitive Impairment by Reducing Lipid Accumulation and Promoting Mitochondrial Fusion via FABP4/Mfn1 Signaling in Microglia

DOI: 10.3390/antiox12010074

Sample: hippocampal tissues
Antioxidants (2022) IF: 7.675
Comprehensive Effect of Carbon Tetrachloride and Reversal of Gandankang Formula in Mice Liver: Involved in Oxidative Stress, Excessive Inflammation, and Intestinal Microflora

DOI: 10.3390/antiox11112234

Sample: liver,serum
SCIENCE OF THE TOTAL ENVIRONMENT (2022) IF: 7.963
Suppression of NADPH oxidase 4 inhibits PM2.5-induced cardiac fibrosis through ROS-P38 MAPK pathway

DOI: 10.1016/j.scitotenv.2022.155558

PMID: 35504386
Sample: lungs,serum,,hearts
AMERICAN JOURNAL OF CHINESE MEDICINE (2022) IF: 6.005
Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-κ B Signaling Pathway

DOI: 10.1142/S0192415X2250094X

Sample: serum
FREE RADICAL BIOLOGY AND MEDICINE (2018) IF: 6.02
Procyanidin B2 ameliorates free fatty acids-induced hepatic steatosis through regulating TFEB-mediated lysosomal pathway and redox state

DOI: 10.1016/j.freeradbiomed.2018.08.024

Sample: serum
ANALYTICAL CHEMISTRY (2018) IF: 6.042
A Redox-Responsive Self-Assembled Nanoprobe for Photoacoustic Inflammation Imaging to Assess Atherosclerotic Plaque Vulnerability

DOI: 10.1021/acs.analchem.8b04912

PMID: 30497260
Sample: Cell culture supernatant
Frontiers in Cardiovascular Medicine (2021) IF: 6.05
Long Non-coding RNA N1LR Protects Against Myocardial Ischemic/Reperfusion Injury Through Regulating the TGF-β Signaling Pathway

DOI: 10.3389/fcvm.2021.654969

PMID: 34485393
Sample: serum
Neural Regeneration Research (2022) IF: 6.058
Sphingosine 1-phosphate receptor 1 regulates bloodbrain barrier permeability in epileptic mice

DOI: 10.4103/1673-5374.360263

Sample: hippocampal tissue
Frontiers in Microbiology (2022) IF: 6.064
Recombinant Listeria ivanovii strain expressing listeriolysin O in place of ivanolysin O might be a potential antigen carrier for vaccine construction

DOI: 10.3389/fmicb.2022.962326

PMID: 35935244
Sample: splenocytes
BIOCHEMICAL PHARMACOLOGY (2023) IF: 6.1
Inhibition of circular RNA ASPH reduces the proliferation and promotes the apoptosis of hepatic stellate cells in hepatic fibrosis

DOI: 10.1016/j.bcp.2023.115451

Sample: serum
Cancers (2020) IF: 6.126
Retinol-Binding Protein 4 Accelerates Metastatic Spread and Increases Impairment of Blood Flow in Mouse Mammary Gland Tumors

DOI: 10.3390/cancers12030623

Sample: 4T1 cell-xenograft
ACTA PHARMACOLOGICA SINICA (2021) IF: 6.15
Luteolin alleviates cognitive impairment in Alzheimer’s disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation

DOI: 10.1038/s41401-021-00702-8

Sample: brain
FREE RADICAL BIOLOGY AND MEDICINE (2020) IF: 6.17
Dry eye induced by exposure to cigarette smoke pollution: An in vivo and in vitro study

DOI: 10.1016/j.freeradbiomed.2020.04.007

PMID: 32320747
Sample: Cell lysate,Cell culture supernatant
JOURNAL OF MEDICINAL CHEMISTRY (2020) IF: 6.205
Small-Molecule Antagonist Targeting Exportin-1 via Rational Structure-Based Discovery

DOI: 10.1021/acs.jmedchem.9b01663

Sample: serum
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208
Treadmill Exercise Reduces Neuroinflammation, Glial Cell Activation and Improves Synaptic Transmission in the Prefrontal Cortex in 3 × Tg-AD Mice

DOI: 10.3390/ijms232012655

Sample: cortex samples
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023) IF: 6.208
The Mechanism of Two Benzaldehydes from Aspergillus terreus C23-3 Improve Neuroinflammatory and Neuronal Damage to Delay the Progression of Alzheimer’s Disease

DOI: 10.3390/ijms24020905

Sample: BV-2 cell
Arabian Journal of Chemistry (2023) IF: 6.212
A pair of new enantiomeric hybrid phthalide–adenines with a rare 5-oxa-1-azaspiro[3,4]octane moiety and two pairs of new enantiomeric hybrid paraethyl phenol–adenines from Ligusticum chuanxiong

DOI: 10.1016/j.arabjc.2023.104696

Sample: RAW264.7 cell
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2020) IF: 6.291
Silica particles disorganize the polarization of pulmonary macrophages in mice

DOI: 10.1016/j.ecoenv.2020.110364

PMID: 32114243
Sample: Tissue homogenate
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2022) IF: 6.291
Diet composition affects long-term zearalenone exposure on the gut–blood–liver axis metabolic dysfunction in mice

DOI: 10.1016/j.ecoenv.2022.113466

Sample: serum
CEPHALALGIA (2021) IF: 6.295
The gut microbiome modulates nitroglycerin-induced migraine-related hyperalgesia in mice:

DOI: 10.1177/03331024211050036

Sample: trigeminal nucleus caudalis (TNC)
Antioxidants (2021) IF: 6.313
Aronia melanocarpa Extract Fermented by Lactobacillus plantarum EJ2014 Modulates Immune Response in Mice

DOI: 10.3390/antiox10081276

PMID: 34439524
Sample: plasma
Food & Function (2023) IF: 6.317
DHA-enriched phosphatidylserine alleviates high fat diet-induced jejunum injury in mice by modulating gut microbiota

DOI: 10.1039/D2FO03019E

Sample: serum
Food & Function (2022) IF: 6.317
DHA-enriched phosphatidylcholine from Clupea harengus roes regulates the gut–liver axis to ameliorate high-fat diet-induced non-alcoholic fatty liver disease

DOI: 10.1039/D2FO02672D

Sample: liver
Pharmaceutics (2021) IF: 6.321
Enhancement of Rotator Cuff Healing with Farnesol-Impregnated Gellan Gum/Hyaluronic Acid Hydrogel Membranes in a Rabbit Model

DOI: 10.3390/pharmaceutics13070944

PMID: 34202556
Sample: C2C12 myoblasts
Journal of Materials Chemistry B (2021) IF: 6.331
The role of micro-vibration parameters in inflammatory responses of macrophages cultured on biphasic calcium phosphate ceramics and the resultant influence on osteogenic differentiation of mesenchymal stem cells

DOI: 10.1039/D1TB00898F

PMID: 34476430
Sample: RAW 264.7 cell
JOURNAL OF CELLULAR PHYSIOLOGY (2021) IF: 6.384
STING-mediated inflammation contributes to Gao binge ethanol feeding model

DOI: 10.1002/jcp.30606

PMID: 34698390
Sample: RAW264.7 cell
PHYTOTHERAPY RESEARCH (2022) IF: 6.388
Indirubin regulates T cell differentiation by promoting αVβ8 expression in bone marrow-derived dendritic cells to alleviate inflammatory bowel disease

DOI: 10.1002/ptr.7595

PMID: 36161389
Sample: serum,dendritic cell (DCs)
International Journal of Nanomedicine (2022) IF: 6.4
Pseudoephedrine Nanoparticles Alleviate Adriamycin-Induced Reproductive Toxicity Through the GnRhR Signaling Pathway

DOI: 10.2147/IJN.S348673

PMID: 35401001
Sample: testes
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2022) IF: 6.51
An ameliorated anti-hTNF-α therapy for arthritis via carrier-free macromolecular nanoparticles consisted of infliximab

DOI: 10.1016/j.ijpharm.2022.122414

Sample: knee joint
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021) IF: 6.514
Design, synthesis, and biological evaluation of carbamate derivatives of N-salicyloyl tryptamine as multifunctional agents for the treatment of Alzheimer's disease

DOI: 10.1016/j.ejmech.2021.114044

PMID: 34923430
Sample: BV2 cell
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021) IF: 6.514
Design and synthesis of 7-O-1,2,3-triazole hesperetin derivatives to relieve inflammation of acute liver injury in mice

DOI: 10.1016/j.ejmech.2021.113162

PMID: 33493826
Sample: Cell culture supernatant
BIOMEDICINE & PHARMACOTHERAPY (2019) IF: 6.53
Inhibition of HDAC6 attenuates LPS-induced inflammation in macrophages by regulating oxidative stress and suppressing the TLR4-MAPK/NF-κB pathways

DOI: 10.1016/j.biopha.2019.109166

PMID: 31255993
Sample: Cell culture supernatant
BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 6.53
Forsythiaside A alleviated carbon tetrachloride-induced liver fibrosis by modulating gut microbiota composition to increase short-chain fatty acids and restoring bile acids metabolism disorder

DOI: 10.1016/j.biopha.2022.113185

PMID: 35623173
Sample: serum
BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 6.53
Ephedra herb reduces adriamycin-induced testicular toxicity by upregulating the gonadotropin-releasing hormone signalling pathway

DOI: 10.1016/j.biopha.2022.113061

PMID: 35658231
Sample: serum
BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53
Curcumin modulates multiple cell death, matrix metalloproteinase activation and cardiac protein release in susceptible and resistant Plasmodium berghei-infected mice

DOI: 10.1016/j.biopha.2021.112454

PMID: 34894518
Sample: serum
BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53
Compound Danshen Dripping Pill inhibits doxorubicin or isoproterenol-induced cardiotoxicity

DOI: 10.1016/j.biopha.2021.111531

PMID: 34311530
Sample: serum
BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 6.53
Activation of α7nAChR preserves intestinal barrier integrity by enhancing the HO-1 / STAT3 signaling to inhibit NF-κB activation in mice

DOI: 10.1016/j.biopha.2022.112733

PMID: 36068769
Sample: Serum
Oxidative Medicine and Cellular Longevity (2021) IF: 6.543
Vitamin B12 Attenuates Acute Pancreatitis by Suppressing Oxidative Stress and Improving Mitochondria Dysfunction via CBS/SIRT1 Pathway

DOI: 10.1155/2021/7936316

PMID: 34925701
Sample: Primary acinar cell
Oxidative Medicine and Cellular Longevity (2022) IF: 6.543
Preventive Effect of Collagen Peptides from Acaudina molpadioides on Acute Kidney Injury through Attenuation of Oxidative Stress and Inflammation

DOI: 10.1155/2022/8186838

PMID: 35592533
Sample: serum
Oxidative Medicine and Cellular Longevity (2021) IF: 6.543
Low-Dose Copper Exposure Exacerbates Depression-Like Behavior in ApoE4 Transgenic Mice

DOI: 10.1155/2021/6634181

PMID: 33833851
Sample: Tissue homogenate(brains)
Oxidative Medicine and Cellular Longevity (2022) IF: 6.543
Ketone Body β-Hydroxybutyrate Prevents Myocardial Oxidative Stress in Septic Cardiomyopathy

DOI: 10.1155/2022/2513837

PMID: 35340211
Sample: H9C2 Cell
Oxidative Medicine and Cellular Longevity (2016) IF: 6.543
Hydrogen Sulfide Mitigates Kidney Injury in High Fat Diet-Induced Obese Mice

DOI: 10.1155/2016/2715718

Sample: Plasma
Oxidative Medicine and Cellular Longevity (2022) IF: 6.543
Exosomal miR-17-3p Alleviates Programmed Necrosis in Cardiac Ischemia/Reperfusion Injury by Regulating TIMP3 Expression

DOI: 10.1155/2022/2785113

PMID: 35116091
Sample: myocardial tissue
Frontiers in Nutrition (2022) IF: 6.576
Using Collagen Peptides From the Skin of Monkfish (Lophius litulon) to Ameliorate Kidney Damage in High-Fat Diet Fed Mice by Regulating the Nrf2 Pathway and NLRP3 Signaling

DOI: 10.3389/fnut.2022.798708

Sample: kidney
Frontiers in Nutrition (2022) IF: 6.59
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism

DOI: 10.3389/fnut.2022.893344

Sample: Serum
Cells (2021) IF: 6.6
Roles of Crosstalk between Astrocytes and Microglia in Triggering Neuroinflammation and Brain Edema Formation in 1,2-Dichloroethane-Intoxicated Mice

DOI: 10.3390/cells10102647

PMID: 34685627
Sample: cerebral tissue
PHYTOMEDICINE (2022) IF: 6.656
Treatment of ulcerative colitis with Wu-Mei-Wan by inhibiting intestinal inflammatory response and repairing damaged intestinal mucosa

DOI: 10.1016/j.phymed.2022.154362

PMID: 35947900
Sample: serum
PHYTOMEDICINE (2022) IF: 6.656
Total terpenoids of Inula japonica activated the Nrf2 receptor to alleviate the inflammation and oxidative stress in LPS-induced acute lung injury

DOI: 10.1016/j.phymed.2022.154377

PMID: 36116200
Sample: lung
PHYTOMEDICINE (2022) IF: 6.656
Total flavonoids of Inula japonica alleviated the inflammatory response and oxidative stress in LPS-induced acute lung injury via inhibiting the sEH activity: Insights from lipid metabolomics

DOI: 10.1016/j.phymed.2022.154380

PMID: 36150346
Sample: lung
PHYTOMEDICINE (2022) IF: 6.656
Integration of transdermal chemistry and network pharmacology to decipher the mechanism of ShexiangZhuifeng analgesic plaster to treat rheumatoid arthritis

DOI: 10.1016/j.phymed.2022.154507

PMID: 36334391
Sample: RAW264.7 cells
Nutrients (2022) IF: 6.706
Cornuside Is a Potential Agent against Alzheimer’s Disease via Orchestration of Reactive Astrocytes

DOI: 10.3390/nu14153179

Sample: cerebral tissue,BV2 cell
LIFE SCIENCES (2023) IF: 6.78
Immuno-metabolic effect of pancreastatin inhibitor PSTi8 in diet induced obese mice: In vitro and in vivo findings

DOI: 10.1016/j.lfs.2023.121415

Sample: serum
Biomaterials Science (2021) IF: 6.843
Supramolecular copolymer modified statin-loaded discoidal rHDLs for atherosclerotic anti-inflammatory therapy by cholesterol efflux and M2 macrophage polarization

DOI: 10.1039/D1BM00610J

PMID: 34346410
Sample: RAW 264.7 cell
Biomaterials Science (2021) IF: 6.843
Resolving the hepatic fibrosis via suppressing oxidative stress and inflammatory response by novel hyaluronic acid modified nanocomplex

DOI: 10.1039/D1BM01499D

Sample: serum
Journal of Inflammation Research (2021) IF: 6.922
Histone Deacetylase 6 Regulates the Activation of M1 Macrophages by the Glycolytic Pathway During Acute Liver Failure

DOI: 10.2147/JIR.S302391

Sample: liver,RAW264.7 cell
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 6.953
Structures and immunomodulatory activity of one galactose- and arabinose-rich polysaccharide from Sambucus adnata

DOI: 10.1016/j.ijbiomac.2022.03.132

PMID: 35346678
Sample: RAW264.7 cell
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021) IF: 6.953
Structural characterization and immunomodulatory activities of two polysaccharides from Rehmanniae Radix Praeparata

DOI: 10.1016/j.ijbiomac.2021.06.100

PMID: 34197855
Sample: RAW264.7 cells
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021) IF: 6.953
Nitraria tangutorum Bobr.-derived polysaccharides protect against LPS-induced lung injury

DOI: 10.1016/j.ijbiomac.2021.06.181

PMID: 34216671
Sample: lung
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 6.953
A monomeric polysaccharide from Polygonatum sibiricum improves cognitive functions in a model of Alzheimer's disease by reshaping the gut microbiota

DOI: 10.1016/j.ijbiomac.2022.05.185

PMID: 35661666
Sample: intestines
Oncotarget (2016) IF: 5.008
Beauveria attenuates asthma by inhibiting inflammatory response and inducing lymphocytic cell apoptosis

DOI: 10.18632/oncotarget.12958

Sample: serum,lymphocytes
LIFE SCIENCES (2021) IF: 5.037
Pancreastatin induces hepatic steatosis in type 2 diabetes by impeding mitochondrial functioning

DOI: 10.1016/j.lfs.2021.119905

PMID: 34453940
Sample: serum
LIFE SCIENCES (2020) IF: 5.037
Fenugreek attenuates obesity-induced inflammation and improves insulin resistance through downregulation of iRhom2/TACE

DOI: 10.1016/j.lfs.2020.118222

PMID: 32768577
Sample: Serum
LIFE SCIENCES (2021) IF: 5.037
Demethylenetetrahydroberberine alleviates nonalcoholic fatty liver disease by inhibiting the NLRP3 inflammasome and oxidative stress in mice

DOI: 10.1016/j.lfs.2021.119778

PMID: 34192596
Sample: serum
Oxidative Medicine and Cellular Longevity (2020) IF: 5.076
The Inhibition of P-Selectin Reduced Severe Acute Lung Injury in Immunocompromised Mice

DOI: 10.1155/2020/8430465

PMID: 32377309
Sample: Serum
INFLAMMOPHARMACOLOGY (2022) IF: 5.093
Nebivolol elicits a neuroprotective effect in the cuprizone model of multiple sclerosis in mice: emphasis on M1/M2 polarization and inhibition of NLRP3 inflammasome activation

DOI: 10.1007/s10787-022-01045-4

PMID: 35948811
Sample: brain
Marine Drugs (2022) IF: 5.118
Monkfish Peptides Mitigate High Fat Diet-Induced Hepatic Steatosis in Mice

DOI: 10.3390/md20050312

PMID: 35621963
Sample: hepatic
Marine Drugs (2022) IF: 5.118
In Vitro and In Vivo Dendritic Cell Immune Stimulation Effect of Low Molecular Weight Fucoidan from New Zealand Undaria pinnatifida

DOI: 10.3390/md20030197

PMID: 35323496
Sample: Dendritic cells (DCs)
Food Science and Human Wellness (2022) IF: 5.154
Selenium-enriched oolong tea (Camellia sinensis) extract exerts anti-inflammatory potential via targeting NF-κB and MAPK pathways in macrophages

DOI: 10.1016/j.fshw.2021.12.020

Sample: RAW264.7 cell
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016) IF: 5.158
The TIR/BB-loop mimetic AS-1 attenuates mechanical stress-induced cardiac fibroblast activation and paracrine secretion via modulation of large tumor suppressor kinase 1

DOI: 10.1016/j.bbadis.2016.03.002

Sample: Cell culture supernatant
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020) IF: 5.162
A novel polysaccharide from Acorus tatarinowii protects against LPS-induced neuroinflammation and neurotoxicity by inhibiting TLR4-mediated MyD88/NF-κB and PI3K/Akt signaling pathways

DOI: 10.1016/j.ijbiomac.2020.06.266

PMID: 32621930
Sample: Cell culture supernatant
Arabian Journal of Chemistry (2022) IF: 5.165
Size, surface charge and flexibility of vinegar-baked Radix Bupleuri polysaccharide affecting the immune response

DOI: 10.1016/j.arabjc.2022.104008

Sample: RAW264.7 cell
Oncotarget (2017) IF: 5.168
λ-Carrageenan improves the antitumor effect of dendritic cellbased vaccine

DOI: 10.18632/oncotarget.15610

Sample: Dendritic cell
Oncotarget (2017) IF: 5.168
Wu-tou decoction attenuates neuropathic pain via suppressing spinal astrocytic IL-1R1/TRAF6/JNK signaling

DOI: 10.18632/oncotarget.21638

Sample: Tissue homogenate
Oncotarget (2017) IF: 5.168
Regulatory role of NKG2D+ NK cells in intestinal lamina propria by secreting double-edged Th1 cytokines in ulcerative colitis

DOI: 10.18632/oncotarget.22132

Sample: Tissue homogenate
FASEB JOURNAL (2021) IF: 5.192
Emodin inhibits lipid accumulation and inflammation in adipose tissue of high-fat diet-fed mice by inducing M2 polarization of adipose tissue macrophages

DOI: 10.1096/fj.202100157RR

PMID: 34110631
Sample: serum,macrophage cells
FASEB JOURNAL (2021) IF: 5.192
Apela inhibits systemic and renal inflammatory reactions in mice with type I cardiorenal syndrome

DOI: 10.1096/fj.202101030R

PMID: 34516679
Sample: plasma
JOURNAL OF ETHNOPHARMACOLOGY (2022) IF: 5.195
The dichloromethane extract of Callicarpa longissima rich in diterpenoid phenols exerts anti-inflammatory effect via inhibiting the TLR4/NF-κB signaling pathway

DOI: 10.1016/j.jep.2022.116124

Sample: RAW264.7 cells
JOURNAL OF ETHNOPHARMACOLOGY (2022) IF: 5.195
Tanreqing injection protects against bleomycin-induced pulmonary fibrosis via inhibiting STING-mediated endoplasmic reticulum stress signaling pathway

DOI: 10.1016/j.jep.2022.116071

Sample: serum
JOURNAL OF ETHNOPHARMACOLOGY (2022) IF: 5.195
Qingre Huoxue Decoction regulates macrophage polarisation to attenuate atherosclerosis through the inhibition of NF-κB signalling-mediated inflammation

DOI: 10.1016/j.jep.2022.115787

PMID: 36206868
Sample: serum
EUROPEAN JOURNAL OF PHARMACOLOGY (2022) IF: 5.195
Orally administered MOTS-c analogue ameliorates dextran sulfate sodium-induced colitis by inhibiting inflammation and apoptosis

DOI: 10.1016/j.ejphar.2022.175469

Sample: plasma
JOURNAL OF ETHNOPHARMACOLOGY (2022) IF: 5.195
Integrated systematic pharmacology analysis and experimental validation to reveal the mechanism of action of Semen aesculi on inflammatory bowel diseases

DOI: 10.1016/j.jep.2022.115627

PMID: 35985613
Sample: plasma,RAW264.7 cell
JOURNAL OF ETHNOPHARMACOLOGY (2023) IF: 5.195
Immunomodulatory effects and mechanisms of Tiepishihu Xiyangshen granules on cyclophosphamide induced immuno-suppression via TLR4/MAPKs and PI3K/AKT/FOXO3a signal pathways

DOI: 10.1016/j.jep.2023.116192

Sample: serum
CLINICAL SCIENCE (2020) IF: 5.223
DNMT3b-mediated methylation of ZSWIM3 enhances inflammation in alcohol-induced liver injury via regulating TRAF2-mediated NF-κB pathway

DOI: 10.1042/CS20200031

Sample: RAW264.7 cell
CNS Neuroscience & Therapeutics (2022) IF: 5.243
Inhibition of phosphodiesterase-4 in the spinal dorsal horn ameliorates neuropathic pain via cAMP-cytokine-Cx43 signaling in mice

DOI: 10.1111/cns.13807

Sample: spinal cord
NEUROPHARMACOLOGY (2022) IF: 5.251
PEA-OXA ameliorates allodynia, neuropsychiatric and adipose tissue remodeling induced by social isolation

DOI: 10.1016/j.neuropharm.2022.108978

PMID: 35157898
Sample: Mesenchymal stromal cells (MSCs)
BIOORGANIC CHEMISTRY (2022) IF: 5.275
Twelve novel sesquiterpenes with anti-inflammatory and cholesterol-lowering activities from burdock leaves

DOI: 10.1016/j.bioorg.2022.105940

PMID: 35749853
Sample: RAW264.7 cell
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021) IF: 5.279
Probiotic Bacillus cereus Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice through Improvement of the Intestinal Barrier Function, Anti-Inflammation, and Gut Microbiota Modulation

DOI: 10.1021/acs.jafc.1c03375

PMID: 34677958
Sample: colon tissue
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2022) IF: 5.279
Laminaria japonica Polysaccharide Suppresses Atherosclerosis via Regulating Autophagy-Mediated Macrophage Polarization

DOI: 10.1021/acs.jafc.1c07483

PMID: 35167294
Sample: aortic,Raw264.7 cell
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2022) IF: 5.279
Industrially Produced Rice Protein Ameliorates Dextran Sulfate Sodium-Induced Colitis via Protecting the Intestinal Barrier, Mitigating Oxidative Stress, and Regulating Gut Microbiota

DOI: 10.1021/acs.jafc.2c00585

Sample: Colon tissue
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021) IF: 5.279
Algal Oil Rich in Docosahexaenoic Acid Alleviates Intestinal Inflammation Induced by Antibiotics Associated with the Modulation of the Gut Microbiome and Metabolome

DOI: 10.1021/acs.jafc.0c07323

PMID: 33900083
Sample: Tissue homogenate(colon)
Frontiers in Cellular and Infection Microbiology (2021) IF: 5.293
Fecal Microbiota Transplantation Protects the Intestinal Mucosal Barrier by Reconstructing the Gut Microbiota in a Murine Model of Sepsis

DOI: 10.3389/fcimb.2021.736204

Sample: serum
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2022) IF: 5.295
Osteocytic cells exposed to titanium particles increase sclerostin expression and inhibit osteoblastic cell differentiation mostly via direct cell-to-cell contact

DOI: 10.1111/jcmm.17460

PMID: 35762300
Sample: MLO-Y4 cell,MC3T3-E1cell
BIOORGANIC CHEMISTRY (2022) IF: 5.307
Synthesis of mitochondria-targeted ferulic acid amide derivatives with antioxidant, anti-inflammatory activities and inducing mitophagy

DOI: 10.1016/j.bioorg.2022.106037

PMID: 35863132
Sample: RAW264.7 cell
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021) IF: 5.31
Verapamil inhibits early acute liver failure through suppressing the NLRP3 inflammasome pathway

DOI: 10.1111/jcmm.16357

PMID: 34031983
Sample: Tissue homogenate
Food Bioscience (2023) IF: 5.318
A comparative study of fermented buffalo and camel milk with anti-inflammatory, ACE-inhibitory and anti-diabetic properties and release of bio active peptides with molecular interactions: In vitro, in silico and molecular study

DOI: 10.1016/j.fbio.2023.102373

Sample: RAW 264.7 cell
PHYTOMEDICINE (2022) IF: 5.34
Tetrahydrocurcumin improves lipopolysaccharide-induced myocardial dysfunction by inhibiting oxidative stress and inflammation via JNK/ERK signaling pathway regulation

DOI: 10.1016/j.phymed.2022.154283

PMID: 35779282
Sample: serum
PHYTOMEDICINE (2021) IF: 5.34
Bioactive constituents of Mosla chinensis-cv. Jiangxiangru ameliorate inflammation through MAPK signaling pathways and modify intestinal microbiota in DSS-induced colitis mice

DOI: 10.1016/j.phymed.2021.153804

PMID: 34735907
Sample: colon tissue
Food & Function (2021) IF: 5.396
The effect of lipid metabolism regulator anthocyanins from Aronia melanocarpa on 3T3-L1 preadipocytes and C57BL/6 mice via activating AMPK signaling and gut microbiota

DOI: 10.1039/D1FO00907A

PMID: 34114580
Sample: Cell culture supernatant
Food & Function (2022) IF: 5.396
Combined royal jelly 10-hydroxydecanoic acid and aspirin has a synergistic effect against memory deficit and neuroinflammation

DOI: 10.1039/D1FO02397G

PMID: 35142767
Sample: BV-2 cell
Food & Function (2022) IF: 5.396
Bioactivity-guided isolation of the major anthocyanin from Lycium ruthenicum Murr. fruit and its antioxidant activity and neuroprotective effects in vitro and in vivo

DOI: 10.1039/D1FO04095B

PMID: 35233585
Sample: hippocampus
Food & Function (2021) IF: 5.396
Bioactives and their metabolites from Tetrastigma hemsleyanum leaves ameliorate DSS-induced colitis via protecting intestinal barrier, mitigating oxidative stress and regulating gut microbiota

DOI: 10.1039/D1FO02588K

Sample: colon tissue
Food & Function (2022) IF: 5.396
Astilbin from Smilax glabra Roxb. alleviates high-fat diet-induced metabolic dysfunction

DOI: 10.1039/D2FO00060A

PMID: 35388843
Sample: serum
Chinese Medicine (2021) IF: 5.455
Full-length transcriptome analysis reveals the mechanism of acupuncture at PC6 improves cardiac function in myocardial ischemia model

DOI: 10.1186/s13020-021-00465-8

PMID: 34238326
Sample: serum
Chinese Medicine (2022) IF: 5.455
Anti-inflammatory effects of anemonin on acute ulcerative colitis via targeted regulation of protein kinase C-θ

DOI: 10.1186/s13020-022-00599-3

PMID: 35346284
Sample: colon tissues
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018) IF: 5.5
Interferon Regulatory Factor 1 Activates Autophagy to Aggravate Hepatic Ischemia-Reperfusion Injury by Increasing High Mobility Group Box 1 Release

DOI: 10.1159/000491732

Sample: Serum
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018) IF: 5.5
Anti-IFN-γ Antibody Promotes Osteoclastogenesis in Human Bone Marrow Monocyte-Derived Macrophages Co-Cultured with Tuberculosis-Activated Th1 Cells

DOI: 10.1159/000493455

Sample: CD4+T helper 1 cells(Th1 cells),bone marrow monocy
Journal of Translational Medicine (2021) IF: 5.531
Pulmonary midkine inhibition ameliorates sepsis induced lung injury

DOI: 10.1186/s12967-021-02755-z

PMID: 33639987
Sample: Bronchoalveolar Lavage Fluid
Foods (2022) IF: 5.561
Encapsulation of Functional Plant Oil by Spray Drying: Physicochemical Characterization and Enhanced Anti-Colitis Activity

DOI: 10.3390/foods11192993

PMID: 36230069
Sample: serum
FOOD AND CHEMICAL TOXICOLOGY (2023) IF: 5.572
Maternal exposure to a glyphosate-based herbicide impairs placental development through endoplasmic reticulum stress in mice

DOI: 10.1016/j.fct.2023.113640

Sample: Placental tissue
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020) IF: 5.573
Melatonin Derivatives Combat with Inflammation-related Cancer by Targeting the Main Culprit STAT3

DOI: 10.1016/j.ejmech.2020.113027

PMID: 33248852
Sample: Cell culture supernatant
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020) IF: 5.573
Design, synthesis and bioactivity study of N-salicyloyl tryptamine derivatives as multifunctional agents for the treatment of neuroinflammation

DOI: 10.1016/j.ejmech.2020.112217

Sample: BV2 cell,C6 cell
MOLECULAR NEUROBIOLOGY (2022) IF: 5.59
Selective GSK3β Inhibition Mediates an Nrf2-Independent Anti-inflammatory Microglial Response

DOI: 10.1007/s12035-022-02923-2

PMID: 35739410
Sample: SIM-A9 cell
EUROPEAN JOURNAL OF NUTRITION (2021) IF: 5.619
Broccoli microgreens juice reduces body weight by enhancing insulin sensitivity and modulating gut microbiota in high-fat diet-induced C57BL/6J obese mice

DOI: 10.1007/s00394-021-02553-9

PMID: 33866422
Sample: Serum
Frontiers in Molecular Neuroscience (2019) IF: 5.639
Corilagin Interferes With Toll-Like Receptor 3-Mediated Immune Response in Herpes Simplex Encephalitis

DOI: 10.3389/fnmol.2019.00083

Sample: brain tissues,BV-2 cells
FREE RADICAL BIOLOGY AND MEDICINE (2019) IF: 5.657
Oral administration of 3,3′-diselenodipropionic acid prevents thoracic radiation induced pneumonitis in mice by suppressing NF-kB/IL-17/G-CSF/neutrophil axis

DOI: 10.1016/j.freeradbiomed.2019.09.009

Sample: Bronchoalveolar Lavage Fluid,Tissue homogenate
Aging-US (2021) IF: 5.682
Investigating the mechanisms of Modified Xiaoyaosan (tiaogan-liqi prescription) in suppressing the progression of atherosclerosis, by means of integrative pharmacology and experimental validation

DOI: 10.18632/aging.202832

PMID: 33839698
Sample: Plasma
Aging-US (2021) IF: 5.682
CHIP ameliorates cerebral ischemia-reperfusion injury by attenuating necroptosis and inflammation

DOI: 10.18632/aging.203774

PMID: 34905731
Sample: brain
MOLECULAR NEUROBIOLOGY (2022) IF: 5.682
Activation of Angiotensin-converting Enzyme 2 Protects Against Lipopolysaccharide-induced Glial Activation by Modulating Angiotensin-converting Enzyme 2/Angiotensin (1–7)/Mas Receptor Axis

DOI: 10.1007/s12035-022-03061-5

Sample: BV2 cell
Journal of Neuroinflammation (2019) IF: 5.7
Baicalin ameliorates neuroinflammation-induced depressive-like behavior through inhibition of toll-like receptor 4 expression via the PI3K/AKT/FoxO1 pathway

DOI: 10.1186/s12974-019-1474-8

Sample: hippocampus tissue,BV2 cells,primary microglia cel
INTERNATIONAL IMMUNOPHARMACOLOGY (2023) IF: 5.714
C1q/tumor necrosis factor-related protein-6 exerts protective effects on myocardial ischemia–reperfusion injury through the modulation of the Akt-GSK-3β-Nrf2 signaling cascade

DOI: 10.1016/j.intimp.2023.109678

Sample: cardiac muscle tissues,cardiomyocytes
Neurotherapeutics (2018) IF: 5.719
Spatial Training Ameliorates Long-Term Alzheimer’s Disease-Like Pathological Deficits by Reducing NLRP3 Inflammasomes in PR5 Mice

DOI: 10.1007/s13311-018-00698-w

Sample: Tissue homogenate
Nutrients (2021) IF: 5.719
Lithospermum erythrorhizon Alleviates Atopic Dermatitis-like Skin Lesions by Restoring Immune Balance and Skin Barrier Function in 2.4-Dinitrochlorobenzene-Induced NC/Nga Mice

DOI: 10.3390/nu13093209

PMID: 34579088
Sample: Splenocyte
Nutrients (2022) IF: 5.719
Friedelin Alleviates the Pathogenesis of Collagenase-Induced Tendinopathy in Mice by Promoting the Selective Autophagic Degradation of p65

DOI: 10.3390/nu14081673

PMID: 35458235
Sample: serum,tenocytes
Frontiers in Aging Neuroscience (2022) IF: 5.75
Agomelatine Prevents Amyloid Plaque Deposition, Tau Phosphorylation, and Neuroinflammation in APP/PS1 Mice

DOI: 10.3389/fnagi.2021.766410

Sample: hippocampus tissue
CELL PROLIFERATION (2020) IF: 5.753
TNF‐α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury

DOI: 10.1111/cpr.12829

Sample: serum
Journal of Neuroinflammation (2020) IF: 5.793
Systemic exosomal miR-193b-3p delivery attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage in mice

DOI: 10.1186/s12974-020-01745-0

Sample: brain
Frontiers in Pharmacology (2022) IF: 5.811
Wu-Mei-Wan Ameliorates Murine Ulcerative Colitis by Regulating Macrophage Polarization

DOI: 10.3389/fphar.2022.859167

PMID: 35387334
Sample: Serum
Frontiers in Pharmacology (2022) IF: 5.811
The Effect of Shionone on Sepsis-Induced Acute Lung Injury by the ECM1/STAT5/NF-κB Pathway

DOI: 10.3389/fphar.2021.764247

Sample: serum,RAW264.7 cell
Frontiers in Pharmacology (2021) IF: 5.811
Phillygenin Attenuates Carbon Tetrachloride-Induced Liver Fibrosis via Modulating Inflammation and Gut Microbiota

DOI: 10.3389/fphar.2021.756924

PMID: 34621179
Sample: serum
Frontiers in Pharmacology (2022) IF: 5.811
Naringin Interferes Doxorubicin-Induced Myocardial Injury by Promoting the Expression of ECHS1

DOI: 10.3389/fphar.2022.859755

PMID: 35496302
Sample: heart tissue
Frontiers in Pharmacology (2021) IF: 5.811
Excessive Intake of Longan Arillus Alters gut Homeostasis and Aggravates Colitis in Mice

DOI: 10.3389/fphar.2021.640417

PMID: 33841158
Sample: Serum
Frontiers in Pharmacology (2018) IF: 5.811
Emodin Attenuates Lipopolysaccharide-Induced Acute Liver Injury via Inhibiting the TLR4 Signaling Pathway in vitro and in vivo

DOI: 10.3389/fphar.2018.00962

Sample: Cell culture supernatant
Frontiers in Pharmacology (2021) IF: 5.811
Atractylodin Attenuates Dextran Sulfate Sodium-Induced Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting Inflammatory Response Through the MAPK Pathway

DOI: 10.3389/fphar.2021.665376

PMID: 34335244
Sample: RAW264.7 cells
Frontiers in Pharmacology (2022) IF: 5.811
Anti-Epileptic Effect of Crocin on Experimental Temporal Lobe Epilepsy in Mice

DOI: 10.3389/fphar.2022.757729

Sample: cortex,hippocampus
BIOCHEMICAL PHARMACOLOGY (2022) IF: 5.858
Tuftsin ameliorates splenic inflammatory injury by promoting neuropilin-1 in severe acute pancreatitis

DOI: 10.1016/j.bcp.2022.115030

PMID: 35381211
Sample: serum
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2022) IF: 5.875
Inflammation-targeted sialic acid-dexamethasone conjugates for reducing the side effects of glucocorticoids

DOI: 10.1016/j.ijpharm.2022.121900

PMID: 35690305
Sample: kidney
PHYTOTHERAPY RESEARCH (2021) IF: 5.882
Erianin inhibits human lung cancer cell growth via PI3K/Akt/mTOR pathway in vitro and in vivo

DOI: 10.1002/ptr.7154

PMID: 34236105
Sample: LLC cell-Xenograft
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2022) IF: 5.895
Transcriptomic Analysis Reveals Lactobacillus reuteri Alleviating Alcohol-Induced Liver Injury in Mice by Enhancing the Farnesoid X Receptor Signaling Pathway

DOI: 10.1021/acs.jafc.2c05591

PMID: 36154116
Sample: serum
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2022) IF: 5.895
Rice Protein Peptides Alleviate Dextran Sulfate Sodium-Induced Colitis via the Keap1–Nrf2 Signaling Pathway and Regulating Gut Microbiota

DOI: 10.1021/acs.jafc.2c04862

Sample: colon tissue
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021) IF: 5.924
Terazosin Stimulates Pgk1 to Remedy Gastrointestinal Disorders

DOI: 10.3390/ijms23010416

PMID: 35008842
Sample: colon tissue
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021) IF: 5.924
Deacetylasperulosidic Acid Ameliorates Pruritus, Immune Imbalance, and Skin Barrier Dysfunction in 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis NC/Nga Mice

DOI: 10.3390/ijms23010226

PMID: 35008651
Sample: serum,Splenocyte
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 5.924
Anti-Obesity and Anti-Hyperglycemic Effects of Meretrix lusoria Protamex Hydrolysate in ob/ob Mice

DOI: 10.3390/ijms23074015

PMID: 35409375
Sample: serum
ANTIVIRAL RESEARCH (2019) IF: 5.97
N-Acetyl cysteine effectively alleviates Coxsackievirus B-Induced myocarditis through suppressing viral replication and inflammatory response

DOI: 10.1016/j.antiviral.2019.104699

Sample: heart
Frontiers in Pharmacology (2022) IF: 5.988
MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation

DOI: 10.3389/fphar.2022.978587

PMID: 36091773
Sample: BV-2 cell
Frontiers in Pharmacology (2022) IF: 5.988
Midazolam Ameliorates Acute Liver Injury Induced by Carbon Tetrachloride via Enhancing Nrf2 Signaling Pathway

DOI: 10.3389/fphar.2022.940137

PMID: 35873576
Sample: liver
Frontiers in Pharmacology (2022) IF: 5.988
Metformin Improves the Senescence of Renal Tubular Epithelial Cells in a High-Glucose State Through E2F1

DOI: 10.3389/fphar.2022.926211

PMID: 35814218
Sample: renal cortical
Frontiers in Aging Neuroscience (2015) IF: 4
PGC-1 silencing compounds the perturbation of mitochondrial function caused by mutant SOD1 in skeletal muscle of ALS mouse model

DOI: 10.3389/fnagi.2015.00204

Sample: Serum
JOURNAL OF NATURAL PRODUCTS (2022) IF: 4.05
A Natural Plant Ingredient, Menthone, Regulates T Cell Subtypes and Lowers Pro-inflammatory Cytokines of Rheumatoid Arthritis

DOI: 10.1021/acs.jnatprod.1c01231

PMID: 35302365
Sample: blood
American Journal of Translational Research (2019) IF: 4.06
Xiaoyaosan prevents atherosclerotic vulnerable plaque formation through heat shock protein/glucocorticoid receptor axis-mediated mechanism

PMID: 31632527
Sample: serum
American Journal of Translational Research (2019) IF: 4.06
Vascular endothelial Cdc42 deficiency delays skin wound-healing processes by increasing IL-1β and TNF-α expression

PMID: 30787984
Sample: skin tissues
American Journal of Translational Research (2021) IF: 4.06
Upregulation of the P2X7 receptor promotes Ca2+ accumulation and inflammatory response in post-stroke depression

PMID: 34650696
Sample: serum
CARBOHYDRATE POLYMERS (2015) IF: 4.074
Structural analysis and immunoregulation activity comparison of five polysaccharides from Angelica sinensis

DOI: 10.1016/j.carbpol.2015.12.050

Sample: Cell culture supernatant
BRAIN RESEARCH BULLETIN (2021) IF: 4.079
Sesamin suppresses advanced glycation end products induced microglial reactivity using BV2 microglial cell line as a model

DOI: 10.1016/j.brainresbull.2021.04.012

PMID: 33894297
Sample: Cell culture medium
BRAIN RESEARCH BULLETIN (2021) IF: 4.079
Geniposide protects depression through BTK/JAK2/STAT1 signaling pathway in lipopolysaccharide-induced depressive mice

DOI: 10.1016/j.brainresbull.2021.02.008

PMID: 33561536
Sample: Serum,Cell culture supernatant,Tissue homogenate
BIOCHIMIE (2021) IF: 4.079
Ex vivo tolerization and M2 polarization of macrophages dampens both pro- and anti-inflammatory cytokine production in response to diabetic wound fluid stimulation

DOI: 10.1016/j.biochi.2021.12.009

Sample: wound fluid,J774A.1 monocytic cell
BIOLOGICAL TRACE ELEMENT RESEARCH (2022) IF: 4.081
Selenium Supplementation Protects Against Arsenic-Trioxide-Induced Cardiotoxicity Via Reducing Oxidative Stress and Inflammation Through Increasing NAD+ Pool

DOI: 10.1007/s12011-022-03478-y

Sample: heart tissue
Biomolecules (2020) IF: 4.082
Preparation, Characterization, and Immuno-Enhancing Activity of Polysaccharides from Glycyrrhiza uralensis

DOI: 10.3390/biom10010159

PMID: 31963790
Sample: Cell culture supernatant,Cell sample
PHYTOTHERAPY RESEARCH (2020) IF: 4.087
The effect of geniposide on chronic unpredictable mild stress‐induced depressive mice through BTK/TLR4/NF‐κB and BDNF/TrkB signaling pathways

DOI: 10.1002/ptr.6846

Sample: Serum,Tissue homogenate,Cell culture supernatant
Foods (2020) IF: 4.092
Protective Effect of Prunus mume Fermented with Mixed Lactic Acid Bacteria in Dextran Sodium Sulfate-Induced Colitis

DOI: 10.3390/foods10010058

PMID: 33383792
Sample: colon tissue,serum
INFLAMMATION (2022) IF: 4.092
Mesenchymal Stem Cells Attenuate Acute Lung Injury in Mice Partly by Suppressing Alveolar Macrophage Activation in a PGE2-Dependent Manner

DOI: 10.1007/s10753-022-01670-9

PMID: 35699823
Sample: BALF,MH-S cell
INFLAMMATION (2022) IF: 4.092
Cannabinoid Analogue WIN 55212–2 Protects Paraquat-Induced Lung Injury and Enhances Macrophage M2 Polarization

DOI: 10.1007/s10753-022-01688-z

Sample: BALF
INFLAMMATION (2021) IF: 4.092
Benzoylaconine Modulates LPS-Induced Responses Through Inhibition of Toll-Like Receptor-Mediated NF-κB and MAPK Signaling in RAW264.7 Cells

DOI: 10.1007/s10753-021-01478-z

Sample: RAW264.7 cells
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2021) IF: 4.101
FXII regulates the formation of deep vein thrombosis via the PI3K/AKT signaling pathway in mice

DOI: 10.3892/ijmm.2021.4920

PMID: 33760144
Sample: femoral vein tissue,plasma
ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119
Upregulation of FAM129B protects cardiomyocytes from hypoxia/reoxygenation-induced injury by inhibiting apoptosis, oxidative stress, and inflammatory response via enhancing Nrf2/ARE activation

DOI: 10.1002/tox.23461

PMID: 34995000
Sample: cardiomyocytes
ENVIRONMENTAL TOXICOLOGY (2021) IF: 4.119
Limonin ameliorates acute pancreatitis by suppressing JAK2/STAT3 signaling pathway

DOI: 10.1002/tox.23352

PMID: 34423886
Sample: serum
ENVIRONMENTAL TOXICOLOGY (2021) IF: 4.119
Inhibition of USP15 ameliorates high-glucose-induced oxidative stress and inflammatory injury in podocytes through regulation of the Keap1/Nrf2 signaling

DOI: 10.1002/tox.23441

PMID: 34931430
Sample: MPC5 cell
ENVIRONMENTAL TOXICOLOGY (2021) IF: 4.119
Effects of 2,4-dichlorophenoxyacetic acid on the expression of NLRP3 inflammasome and autophagy-related proteins as well as the protective effect of Lycium barbarum polysaccharide in neonatal rats

DOI: 10.1002/tox.23358

PMID: 34464015
Sample: BV2 cell
ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119
C1q/tumor necrosis factor-related protein 9 protects cultured chondrocytes from IL-1β-induced inflammatory injury by inhibiting NLRP3 inflammasome activation via the AdipoR1/AMPK axis

DOI: 10.1002/tox.23452

PMID: 34990072
Sample: chondrocytes
ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119
2,4-dichlorophenoxyacetic acid induces ROS activation in NLRP3 inflammatory body-induced autophagy disorder in microglia and the protective effect of Lycium barbarum polysaccharide

DOI: 10.1002/tox.23471

PMID: 35099110
Sample: BV2 cell
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2022) IF: 4.125
Preventive and synbiotic effects of the soluble dietary fiber obtained from Lentinula edodes byproducts and Lactobacillus plantarum LP90 against dextran sulfate sodium-induced colitis in mice

DOI: 10.1002/jsfa.12173

PMID: 36054505
Sample: serum,colon tissue
Food & Function (2020) IF: 4.171
Polyphenol rich extracts of finger millet and kodo millet ameliorate high fat diet-induced metabolic alterations

DOI: 10.1039/D0FO01643H

PMID: 33089852
Sample: Cell culture supernatant
Food & Function (2020) IF: 4.171
Melatonin as an inducer of arecoline and their coordinated roles in anti-oxidative activity and immune responses

DOI: 10.1039/D0FO01841D

PMID: 32955540
Sample: Plasma
Food & Function (2020) IF: 4.171
Flaxseed oligosaccharides alleviate DSS-induced colitis through modulation of gut microbiota and repair of the intestinal barrier in mice

DOI: 10.1039/D0FO01105C

PMID: 32856645
Sample: Serum,Tissue homogenate
Food & Function (2020) IF: 4.171
Akebia trifoliata pericarp extract ameliorates inflammation through NF-κB/MAPK signaling pathways and modifies gut microbiota

DOI: 10.1039/C9FO02917F

Sample: colon tissue
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019) IF: 4.183
Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways

DOI: 10.3390/ijms20051103

PMID: 30836660
Sample: Serum
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019) IF: 4.183
Resveratrol Plays a Protective Role against Premature Ovarian Failure and Prompts Female Germline Stem Cell Survival

DOI: 10.3390/ijms20143605

PMID: 31340581
Sample: Serum,Cell culture supernatant
Transboundary and Emerging Diseases (2020) IF: 4.188
H5N1 avian influenza virus without 80–84 amino acid deletion at the NS1 protein hijacks the innate immune system of dendritic cells for an enhanced mammalian pathogenicity

DOI: 10.1111/tbed.13904

Sample: Cell culture supernatant
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020) IF: 4.192
Novel Biomedical Functions of Surfactin A from Bacillus subtilis in Wound Healing Promotion and Scar Inhibition

DOI: 10.1021/acs.jafc.0c01658

PMID: 32412748
Sample: Cell culture supernatant
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020) IF: 4.192
Modulation of Gut Microbiota by Fucoxanthin During Alleviation of Obesity in High-Fat Diet-Fed Mice

DOI: 10.1021/acs.jafc.0c01467

PMID: 32309947
Sample: Serum,Tissue homogenate
TOXICOLOGY (2021) IF: 4.221
O-alkyl and o-benzyl hesperetin derivative-1L attenuates inflammation and protects against alcoholic liver injury via inhibition of BRD2-NF-κB signaling pathway

DOI: 10.1016/j.tox.2021.153087

PMID: 34974135
Sample: serum,RAW264.7 cell
Frontiers in Pharmacology (2020) IF: 4.225
TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation

DOI: 10.3389/fphar.2020.00010

Sample: serum
Frontiers in Pharmacology (2020) IF: 4.225
Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice.

DOI: 10.3389/fphar.2020.550955

Sample: Tissue Slice
Frontiers in Microbiology (2020) IF: 4.236
Immunization With a Secreted Esterase Protects Mice Against Multiple Serotypes (M1, M3, and M28) of Group A Streptococcus

DOI: 10.3389/fmicb.2020.00565

Sample: skin
Frontiers in Microbiology (2020) IF: 4.236
Algal Oil Rich in n-3 PUFA Alleviates DSS-Induced Colitis via Regulation of Gut Microbiota and Restoration of Intestinal Barrier

DOI: 10.3389/fmicb.2020.615404

Sample: serum
Food Bioscience (2022) IF: 4.24
Exploring the potential of Lactobacillus and Saccharomyces for biofunctionalities and the release of bioactive peptides from whey protein fermentate

DOI: 10.1016/j.fbio.2022.101758

Sample: RAW264.7 cell
Food Bioscience (2021) IF: 4.24
Exploring potentials of antioxidative, anti-inflammatory activities and production of bioactive peptides in lactic fermented camel milk

DOI: 10.1016/j.fbio.2021.101404

Sample: RAW 264.7 cell
Food Bioscience (2022) IF: 4.24
Antioxidative, antimicrobial and anti-inflammatory activities and release of ultra-filtered antioxidative and antimicrobial peptides during fermentation of sheep milk: In-vitro, in-silico and molecular interaction studies

DOI: 10.1016/j.fbio.2022.101666

Sample: RAW 264.7 murine macrophage cell
Scientific Reports (2017) IF: 4.259
Glycyrrhiza uralensis water extract enhances dendritic cell maturation and antitumor efficacy of HPV dendritic cell-based vaccine

DOI: 10.1038/srep43796

Sample: Cell culture supernatant
Frontiers in Microbiology (2019) IF: 4.259
Effect of Perillaldehyde on Prophylaxis and Treatment of Vaginal Candidiasis in a Murine Model

DOI: 10.3389/fmicb.2019.01466

PMID: 31333606
Sample: Tissue homogenate
INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY (2022) IF: 4.286
Identification and molecular mechanisms of novel antioxidative peptides from fermented camel milk (Kachchi breed, India) with anti-inflammatory activity in raw macrophages cell lines

DOI: 10.1111/1471-0307.12911

Sample: RAW 264.7 cells
INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY (2022) IF: 4.286
Antidiabetic, angiotensin-converting enzyme inhibitory and anti-inflammatory activities of fermented camel milk and characterisation of novel bioactive peptides from lactic-fermented camel milk with molecular interaction study

DOI: 10.1111/1471-0307.12910

Sample: RAW 264.7 cell
Drug Design Development and Therapy (2022) IF: 4.319
Guanmaitong Granule Attenuates Atherosclerosis by Inhibiting Inflammatory Immune Response in ApoE^−/− Mice Fed High-Fat Diet

DOI: 10.2147/DDDT.S372143

Sample: serum
International Journal of Nanomedicine (2016) IF: 4.32
Effects of silver nanoparticles in combination with antibiotics on the resistant bacteria Acinetobacter baumannii

DOI: 10.2147/IJN.S104166

Sample: Plasma
Foods (2021) IF: 4.35
Green Pea (Pisum sativum L.) Hull Polyphenol Extracts Ameliorate DSS-Induced Colitis through Keap1/Nrf2 Pathway and Gut Microbiota Modulation

DOI: 10.3390/foods10112765

Sample: colon
DRUG DEVELOPMENT RESEARCH (2021) IF: 4.36
Tanshinol alleviates ulcerative colitis by promoting the expression of VLDLR

DOI: 10.1002/ddr.21840

PMID: 34145621
Sample: colon
JOURNAL OF ETHNOPHARMACOLOGY (2021) IF: 4.36
Protective effect of Di'ao Xinxuekang capsule against doxorubicin-induced chronic cardiotoxicity

DOI: 10.1016/j.jep.2021.114943

PMID: 34954266
Sample: serum
JOURNAL OF ETHNOPHARMACOLOGY (2021) IF: 4.36
In vitro and in vivo relaxation and anti-inflammation of natural flavonoids from Elaeagnus pungens leaf via L-type calcium channel and targeting MAPK signal pathway

DOI: 10.1016/j.jep.2021.114071

PMID: 33831464
Sample: Cell culture supernatant
NEUROPHARMACOLOGY (2019) IF: 4.367
Modulation of LPA1 receptor-mediated neuronal apoptosis by Saikosaponin-d: A target involved in depression

DOI: 10.1016/j.neuropharm.2019.05.027

Sample: hippocampus tissue
Human Cell (2022) IF: 4.374
METTL3 promotes m6A hypermethylation of RBM14 via YTHDF1 leading to the progression of hepatocellular carcinoma

DOI: 10.1007/s13577-022-00769-3

PMID: 36087219
Sample: Kupffer cell (KCs)
TOXICOLOGY LETTERS (2022) IF: 4.374
Adenosine receptor A2B mediates alcoholic hepatitis by regulating cAMP levels and the NF-KB pathway

DOI: 10.1016/j.toxlet.2022.01.012

PMID: 35143882
Sample: serum,RAW264.7 cell
Scientific Reports (2021) IF: 4.38
The protective effect of the PDE-4 inhibitor rolipram on intracerebral haemorrhage is associated with the cAMP/AMPK/SIRT1 pathway

DOI: 10.1038/s41598-021-98743-w

PMID: 34611179
Sample: Brain tissue
Scientific Reports (2021) IF: 4.38
Studies on the mitochondrial, immunological and inflammatory effects of solvent fractions of Diospyros mespiliformis Hochst in Plasmodium berghei-infected mice

DOI: 10.1038/s41598-021-85790-6

PMID: 33767260
Sample: Serum
Scientific Reports (2022) IF: 4.38
Saffron extract and crocin exert anti-inflammatory and anti-oxidative effects in a repetitive mild traumatic brain injury mouse model

DOI: 10.1038/s41598-022-09109-9

PMID: 35322143
Sample: brain
Scientific Reports (2022) IF: 4.38
Mebendazole, an anti-helminth drug, suppresses inflammation, oxidative stress and injury in a mouse model of ulcerative colitis

DOI: 10.1038/s41598-022-14420-6

PMID: 35715495
Sample: colon tissue
Scientific Reports (2021) IF: 4.38
Hepatoprotective effect of Thymus vulgaris extract on sodium nitrite-induced changes in oxidative stress, antioxidant and inflammatory marker expression

DOI: 10.1038/s41598-021-85264-9

PMID: 33707592
Sample: Serum
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2021) IF: 4.399
Attenuation of virulence in multiple serotypes (M1, M3, and M28) of Group A Streptococcus after the loss of secreted esterase

DOI: 10.1016/j.jmii.2021.09.008

PMID: 34674958
Sample: skin lesion
MOLECULAR IMMUNOLOGY (2022) IF: 4.407
The therapeutic potential of chondroitin sulfate in Aspergillus fumigatus keratitis

DOI: 10.1016/j.molimm.2022.04.007

PMID: 35504058
Sample: corneas,RAW 264.7 cell
MOLECULAR IMMUNOLOGY (2021) IF: 4.407
Activation of TLR4 induces severe acute pancreatitis-associated spleen injury via ROS-disrupted mitophagy pathway

DOI: 10.1016/j.molimm.2021.12.012

PMID: 34965485
Sample: serum,spleen tissue
MOLECULES (2022) IF: 4.412
The Expression and Bioinformatics Analysis of Circular RNAs in Endometritis Mouse Uterus Tissues

DOI: 10.3390/molecules27123682

PMID: 35744807
Sample: uterine tissue
MOLECULES (2021) IF: 4.412
Rosmanol and Carnosol Synergistically Alleviate Rheumatoid Arthritis through Inhibiting TLR4/NF-κB/MAPK Pathway

DOI: 10.3390/molecules27010078

Sample: serum
MOLECULES (2022) IF: 4.412
Quercetin-Rich Ethanolic Extract of Polygonum odoratum var Pakphai Leaves Decreased Gene Expression and Secretion of Pro-Inflammatory Mediators in Lipopolysaccharide-Induced Murine RAW264.7 Macrophages

DOI: 10.3390/molecules27123657

PMID: 35744785
Sample: RAW264.7 cell
MOLECULES (2021) IF: 4.412
In Vitro and In Vivo Activity of 14-O-[(4,6-Diamino-pyrimidine-2-yl) thioacetyl] Mutilin against Methicillin-Resistant Staphylococcus aureus

DOI: 10.3390/molecules26113277

Sample: Serum
NEUROCHEMICAL RESEARCH (2022) IF: 4.414
The protective effect of Palmatine on depressive like behavior by modulating microglia polarization in LPS-induced mice

DOI: 10.1007/s11064-022-03672-3

PMID: 35917005
Sample: hippocampus,BV2 cell
JOURNAL OF NUTRITION (2019) IF: 4.416
Lactobacillus acidophilus Exerts Neuroprotective Effects in Mice with Traumatic Brain Injury

DOI: 10.1093/jn/nxz105

PMID: 31174208
Sample: Serum,Tissue homogenate
ACS Chemical Neuroscience (2021) IF: 4.418
Peripheral Administration of a Cell-Penetrating MOTS-c Analogue Enhances Memory and Attenuates Aβ1–42- or LPS-Induced Memory Impairment through Inhibiting Neuroinflammation

DOI: 10.1021/acschemneuro.0c00782

Sample: Tissue homogenate(hippocampus)
NEUROPHARMACOLOGY (2020) IF: 4.431
Seizure-induced neuroinflammation contributes to ectopic neurogenesis and aggressive behavior in pilocarpine-induced status epilepticus mice

DOI: 10.1016/j.neuropharm.2020.108044

PMID: 32179291
Sample: Cell lysate
EUROPEAN JOURNAL OF PHARMACOLOGY (2022) IF: 4.432
Research on the effect and underlying molecular mechanism of Cangzhu in the treatment of gouty arthritis

DOI: 10.1016/j.ejphar.2022.175044

Sample: RAW264.7-cell
EUROPEAN JOURNAL OF PHARMACOLOGY (2022) IF: 4.432
Laccase-mediated functionalization of natamycin by gallic acids for the therapeutic effect on Aspergillus fumigatus keratitis

DOI: 10.1016/j.ejphar.2022.175041

PMID: 35597265
Sample: corneas,RAW264.7 cell
EUROPEAN JOURNAL OF PHARMACOLOGY (2022) IF: 4.432
Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A

DOI: 10.1016/j.ejphar.2022.174749

PMID: 35007522
Sample: serum
Journal of Functional Foods (2021) IF: 4.451
Structural characterization and immunomodulatory activity of a glucan from Radix Codonopsis

DOI: 10.1016/j.jff.2021.104537

Sample: Cell culture supernatant
Journal of Functional Foods (2021) IF: 4.451
N-acetyl-chitooligosaccharide attenuates inflammatory responses by suppression of NF-κB signaling, MAPK and NLRP3 inflammasome in macrophages

DOI: 10.1016/j.jff.2021.104364

Sample: Cell culture medium
Journal of Functional Foods (2021) IF: 4.451
Effect of κ-carrageenan on glucolipid metabolism and gut microbiota in high-fat diet-fed mice

DOI: 10.1016/j.jff.2021.104707

Sample: serum
Journal of Functional Foods (2022) IF: 4.451
Antioxidative mechanisms and anticolitic potential of Desmodium styracifolium (Osb.) Merr. in DSS-induced colitic mice

DOI: 10.1016/j.jff.2022.105077

Sample: colonic tissue
NEUROBIOLOGY OF AGING (2018) IF: 4.454
CIP2A-promoted astrogliosis induces AD-like synaptic degeneration and cognitive deficits

DOI: 10.1016/j.neurobiolaging.2018.11.023

PMID: 30594047
Sample: Tissue homogenate,Cell culture medium
TOXICOLOGY AND APPLIED PHARMACOLOGY (2023) IF: 4.46
Dihydrokaempferol attenuates CCl4-induced hepatic fibrosis by inhibiting PARP-1 to affect multiple downstream pathways and cytokines

DOI: 10.1016/j.taap.2023.116438

Sample: serum
INFLAMMOPHARMACOLOGY (2021) IF: 4.473
Terpene-rich fractions of Ficus mucoso (Welw) modulate lipopolysaccharide-induced inflammatory mediators and aberrant permeability of the inner mitochondrial membrane in murine animal model

DOI: 10.1007/s10787-021-00876-x

PMID: 34613566
Sample: serum
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020) IF: 4.486
Polysaccharides from Dicliptera chinensis ameliorate liver disturbance by regulating TLR‐4/NF‐κB and AMPK/Nrf2 signalling pathways

DOI: 10.1111/jcmm.15286

Sample: Serum,Tissue homogenate
ACS Chemical Neuroscience (2020) IF: 4.486
MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis

DOI: 10.1021/acschemneuro.0c00268

PMID: 32786312
Sample: Serum
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020) IF: 4.486
Defibrotide inhibits donor leucocyte‐endothelial interactions and protects against acute graft‐versus‐host disease

DOI: 10.1111/jcmm.15434

Sample: Plasma
MEDIATORS OF INFLAMMATION (2023) IF: 4.529
Integrative Analysis of Transcriptome and Metabolome to Illuminate the Protective Effects of Didymin against Acute Hepatic Injury

DOI: 10.1155/2023/6051946

Sample: Serum
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
Study on the protective effect and mechanism of Dicliptera chinensis (L.) Juss (Acanthaceae) polysaccharide on immune liver injury induced by LPS

DOI: 10.1016/j.biopha.2020.111159

PMID: 33370627
Sample: Tissue homogenate
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
MG-132 attenuates cardiac deterioration of viral myocarditis via AMPK pathway

DOI: 10.1016/j.biopha.2020.110091

PMID: 32278272
Sample: Plasma
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
Endothelial progenitor cell–derived exosomes ameliorate endothelial dysfunction in a mouse model of diabetes

DOI: 10.1016/j.biopha.2020.110756

Sample: Serum
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
Endothelial progenitor cell–derived exosomes ameliorate endothelial dysfunction in a mouse model of diabetes

DOI: 10.1016/j.biopha.2020.110756

Sample: Serum
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
Dihydrotanshinone attenuates chemotherapy-induced intestinal mucositis and alters fecal microbiota in mice

DOI: 10.1016/j.biopha.2020.110262

Sample: serum
BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
Deletion of macrophage migration inhibitory factor ameliorates inflammation in mice model severe acute pancreatitis

DOI: 10.1016/j.biopha.2020.109919

PMID: 32062385
Sample: Serum
Nutrients (2020) IF: 4.546
Chinese Propolis Prevents Obesity and Metabolism Syndromes Induced by a High Fat Diet and Accompanied by an Altered Gut Microbiota Structure in Mice

DOI: 10.3390/nu12040959

PMID: 32235581
Sample: Serum
Nutrients (2020) IF: 4.546
Bifidobacteria-Fermented Red Ginseng and Its Constituents Ginsenoside Rd and Protopanaxatriol Alleviate Anxiety/Depression in Mice by the Amelioration of Gut Dysbiosis

DOI: 10.3390/nu12040901

PMID: 32224881
Sample: Tissue homogenate
Frontiers in Physiology (2021) IF: 4.566
Osthole Blocks HMGB1 Release From the Nucleus and Confers Protective Effects Against Renal Ischemia-Reperfusion Injury.

DOI: 10.3389/fphys.2021.735425

Sample: renal tissue
Stem Cell Research & Therapy (2019) IF: 4.627
Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity

DOI: 10.1186/s13287-019-1337-3

Sample: ADSC cells
INFLAMMATION (2022) IF: 4.657
Anti-inflammatory Effect of a Limonin Derivative In Vivo and Its Mechanisms in RAW264.7 Cells

DOI: 10.1007/s10753-022-01722-0

PMID: 35986873
Sample: Raw 264.7 cell
MEDIATORS OF INFLAMMATION (2022) IF: 4.711
Curcumin Targeting NF-κB/Ubiquitin-Proteasome-System Axis Ameliorates Muscle Atrophy in Triple-Negative Breast Cancer Cachexia Mice

DOI: 10.1155/2022/2567150

Sample: gastrocnemius tissue,4T2 cell-Xenograft
Frontiers in Immunology (2019) IF: 4.716
Intranasal MMI-0100 Attenuates Aβ1−42- and LPS-Induced Neuroinflammation and Memory Impairments via the MK2 Signaling Pathway

DOI: 10.3389/fimmu.2019.02707

Sample: Tissue homogenate
Frontiers in Physiology (2022) IF: 4.755
Abscopal effects of thoracic X-ray radiation on spermatogenesis in mice

DOI: 10.3389/fphys.2022.984429

PMID: 36091371
Sample: lung,serum,testis
Frontiers in Genetics (2022) IF: 4.772
Construction, bioinformatics analysis, and validation of competitive endogenous RNA networks in ulcerative colitis

DOI: 10.3389/fgene.2022.951243

Sample: Ulcerative colitis (UC) tissue
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019) IF: 4.784
Structural characterisation and immunomodulatory activity of a neutral polysaccharide from Sambucus adnata Wall

DOI: 10.1016/j.ijbiomac.2019.11.021

PMID: 31756460
Sample: Cell culture medium
JOURNAL OF PSYCHIATRIC RESEARCH (2021) IF: 4.791
Lipopolysaccharide exacerbates chronic restraint stress-induced neurobehavioral deficits: Mechanisms by redox imbalance, ASK1-related apoptosis, autophagic dysregulation

DOI: 10.1016/j.jpsychires.2021.10.021

PMID: 34768069
Sample: serum,brain
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2021) IF: 4.799
Isorhamnetin Ameliorates Aspergillus fumigatus Keratitis by Reducing Fungal Load, Inhibiting Pattern-Recognition Receptors and Inflammatory Cytokines

DOI: 10.1167/iovs.62.3.38

PMID: 33783487
Sample: Tissue homogenate(corneas)
JOURNAL OF PHARMACY AND PHARMACOLOGY (2023) IF: 4.81
Inula japonica ameliorated the inflammation and oxidative stress in LPS-induced acute lung injury through the MAPK/NF-κB and Keap1/Nrf2 signalling pathways

DOI: 10.1093/jpp/rgac084

Sample: lung
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020) IF: 4.845
Therapeutic potential of nanolipoidal α-terpineol in combating keratitis induced by Pseudomonas aeruginosa in the murine model

DOI: 10.1016/j.ijpharm.2020.120175

PMID: 33338569
Sample: corneal tissue
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020) IF: 4.845
Targeted delivery of zoledronic acid through the sialic acid - Siglec axis for killing and reversal of M2 phenotypic tumor-associated macrophages – A promising cancer immunotherapy

DOI: 10.1016/j.ijpharm.2020.119929

Sample: Serum,Tissue homogenate
Oxidative Medicine and Cellular Longevity (2019) IF: 4.868
Maggot Extracts Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis via the Activation of Nrf2

DOI: 10.1155/2019/4703253

PMID: 31827675
Sample: Serum
MOLECULES (2022) IF: 4.927
Two Pairs of 7,7′-Cyclolignan Enantiomers with Anti-Inflammatory Activities from Perilla frutescens

DOI: 10.3390/molecules27186102

Sample: Raw 264.7 cell
MOLECULES (2023) IF: 4.927
Neuroprotective Effects of Savinin on LPS-Induced Neuroinflammation In Vivo via Regulating MAPK/NF-κB Pathway and NLRP3 Inflammasome Activation

DOI: 10.3390/molecules28041575

Sample: Serum
MOLECULES (2022) IF: 4.927
Monkfish (Lophius litulon) Peptides Ameliorate High-Fat-Diet-Induced Nephrotoxicity by Reducing Oxidative Stress and Inflammation via Regulation of Intestinal Flora

DOI: 10.3390/molecules28010245

Sample: renal tissue
MOLECULES (2022) IF: 4.927
Ethyl Acetate Extract from Artemisia argyi Prevents Liver Damage in ConA-Induced Immunological Liver Injury Mice via Bax/Bcl-2 and TLR4/MyD88/NF-κB Signaling Pathways

DOI: 10.3390/molecules27227883

Sample: hepatic
MOLECULES (2023) IF: 4.927
Design, Synthesis, and Anti-Inflammatory Activities of 12-Dehydropyxinol Derivatives

DOI: 10.3390/molecules28031307

Sample: RAW264.7 cell
POLYMER TESTING (2022) IF: 4.931
Antioxidant activity analysis of collagen peptide-magnesium chelate

DOI: 10.1016/j.polymertesting.2022.107822

Sample: Raw264.7 cells
INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway

DOI: 10.1016/j.intimp.2021.108238

PMID: 34688152
Sample: RGCs
INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
Quercetin ameliorates Aspergillus fumigatus keratitis by inhibiting fungal growth, toll-like receptors and inflammatory cytokines

DOI: 10.1016/j.intimp.2021.107435

Sample: Tissue homogenate(corneas)
INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways

DOI: 10.1016/j.intimp.2021.107506

PMID: 34022766
Sample: Tissue homogenate(lung),Bronchoalveolar Lavage Flu
INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
Oxymatrine inhibits neuroinflammation by Regulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathway

DOI: 10.1016/j.intimp.2021.108139

Sample: N9 microglial cell
INTERNATIONAL IMMUNOPHARMACOLOGY (2016) IF: 4.932
MiR-146a modulates macrophage polarization by inhibiting Notch1 pathway in RAW264.7 macrophages

DOI: 10.1016/j.intimp.2016.01.009

Sample: Cell culture supernatant
INTERNATIONAL IMMUNOPHARMACOLOGY (2022) IF: 4.932
Inhibition of P2Y6 receptor expression in Kupffer cells alleviates alcoholic steatohepatitis in mice

DOI: 10.1016/j.intimp.2022.108909

PMID: 35700583
Sample: serum,RAW264.7 cell
INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
Hydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice

DOI: 10.1016/j.intimp.2021.107583

PMID: 33773206
Sample: Tissue homogenate(hippocampal tissues)
INTERNATIONAL IMMUNOPHARMACOLOGY (2022) IF: 4.932
High-density lipoprotein reduces microglia activation and protects against experimental autoimmune encephalomyelitis in mice

DOI: 10.1016/j.intimp.2022.108566

PMID: 35101849
Sample: plasma,BV2 microglial cell
INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
Empagliflozin, a sodium glucose cotransporter-2 inhibitor, ameliorates peritoneal fibrosis via suppressing TGF-β/Smad signaling

DOI: 10.1016/j.intimp.2021.107374

PMID: 33517222
Sample: peritoneal dialysis solution,Cell culture supernat
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 4.932
COX-2-PGE2 signaling pathway contributes to hippocampal neuronal injury and cognitive impairment in PTZ-kindled epilepsy mice

DOI: 10.1016/j.intimp.2020.106801

Sample: Tissue homogenate
INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
Bixin protects mice against bronchial asthma though modulating PI3K/Akt pathway

DOI: 10.1016/j.intimp.2021.108266

PMID: 34678694
Sample: BALF
INTERNATIONAL IMMUNOPHARMACOLOGY (2022) IF: 4.932
Atractyloside-A ameliorates spleen deficiency diarrhea by interfering with TLR4/MyD88/NF-κB signaling activation and regulating intestinal flora homeostasis

DOI: 10.1016/j.intimp.2022.108679

PMID: 35279514
Sample: colon tissue
INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
Astragaloside IV ameliorates steroid-induced osteonecrosis of the femoral head by repolarizing the phenotype of pro-inflammatory macrophages

DOI: 10.1016/j.intimp.2020.107345

PMID: 33563553
Sample: Tissue homogenate
INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism

DOI: 10.1016/j.intimp.2021.108413

PMID: 34891003
Sample: plasma
INTERNATIONAL IMMUNOPHARMACOLOGY (2022) IF: 4.932
ACT001 suppressing M1 polarization against inflammation via NF-κB and STAT1 signaling pathways alleviates acute lung injury in mice

DOI: 10.1016/j.intimp.2022.108944

PMID: 35728304
Sample: BALF
BIOCHEMICAL PHARMACOLOGY (2020) IF: 4.96
Perillaldehyde: A promising antifungal agent to treat oropharyngeal candidiasis

DOI: 10.1016/j.bcp.2020.114201

PMID: 32822688
Sample: Tissue homogenate
Scientific Reports (2022) IF: 4.996
Endothelin receptor B enhances liver injury and pro-inflammatory responses by increasing G-protein-coupled receptor kinase-2 expression in primary biliary cholangitis

DOI: 10.1038/s41598-022-21816-x

Sample: serum
Contrast Media & Molecular Imaging (2022) IF: 3.009
lncRNA SNHG12 Inhibition Based on Microsystem Cell Imaging Technology Protects the Endothelium from LPS-Induced Inflammation by Inhibiting the Expression of miR-140-3p Target Gene fndc5

DOI: 10.1155/2022/1681864

PMID: 36034208
Sample: BALF,PMVEC
Cardiovascular Therapeutics (2022) IF: 3.023
L-Carnitine Alleviates the Myocardial Infarction and Left Ventricular Remodeling through Bax/Bcl-2 Signal Pathway

DOI: 10.1155/2022/9615674

PMID: 35692375
Sample: plasma
European Review for Medical and Pharmacological Sciences (2020) IF: 3.024
MiR-181-5p protects mice from sepsis via repressing HMGB1 in an experimental model

DOI: 10.26355/eurrev_202009_23063

PMID: 33015817
Sample: Serum
European Review for Medical and Pharmacological Sciences (2020) IF: 3.024
Effect of β-casomorphin-7 on myocardial hypertrophy in hyperthyroidism-induced cardiomyopathy

DOI: 10.26355/eurrev_202006_21536

PMID: 32572935
Sample: Serum,Tissue homogenate
NEUROCHEMICAL RESEARCH (2020) IF: 3.038
Bexarotene Improve Depression-Like Behaviour in Mice by Protecting Against Neuro-inflammation and Synaptic Damage

DOI: 10.1007/s11064-020-03012-3

PMID: 32170675
Sample: Tissue homogenate
IMMUNOLOGICAL INVESTIGATIONS (2022) IF: 3.044
Knockdown of PHLDA1 Alleviates Necrotizing Enterocolitis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Through Enhancing Nrf2 Signaling

DOI: 10.1080/08820139.2022.2161910

Sample: intestinal tissues
MOLECULES (2019) IF: 3.06
Design, Synthesis and Investigation of the Potential Anti-Inflammatory Activity of 7-O-Amide Hesperetin Derivatives

DOI: 10.3390/molecules24203663

PMID: 31614601
Sample: Cell culture supernatant
American Journal of Translational Research (2018) IF: 3.061
Diosgenin glucoside protects against myocardial injury in diabetic mice by inhibiting RIP140 signaling

PMID: 30662624
Sample: serum,cardiac tissue
BIOORGANIC & MEDICINAL CHEMISTRY (2020) IF: 3.073
Design and synthesis of 1,3-benzothiazinone derivatives as potential anti-inflammatory agents

DOI: 10.1016/j.bmc.2020.115526

Sample: Cell culture supernatant
MOLECULES (2018) IF: 3.098
Nuciferine Inhibits Proinflammatory Cytokines via the PPARs in LPS-Induced RAW264.7 Cells

DOI: 10.3390/molecules23102723

Sample: Cell culture supernatant
FOOD AND AGRICULTURAL IMMUNOLOGY (2020) IF: 3.101
Comparison of structural characteristics and immunoregulatory activities of polysaccharides from four natural plants

DOI: 10.1080/09540105.2020.1743647

Sample: Cell sample,Serum
INTERNATIONAL IMMUNOPHARMACOLOGY (2018) IF: 3.118
Interaction of mannose binding lectin and other pattern recognition receptors in human corneal epithelial cells during Aspergillus fumigatus infection

DOI: 10.1016/j.intimp.2018.08.003

PMID: 30096599
Sample: Tissue homogenate
INTERNATIONAL IMMUNOPHARMACOLOGY (2018) IF: 3.118
B-cell-specific mammalian target of rapamycin complex 1 activation results in severe osteoarthritis in mice

DOI: 10.1016/j.intimp.2018.09.038

Sample: serum
Journal of Pain Research (2022) IF: 3.133
Anti-Nociceptive and Anti-Inflammatory Activities of the Ethyl Acetate Extract of Belamcanda chinensis (L.) Redouté in Raw 264.7 Cells in vitro and Mouse Model in vivo

DOI: 10.2147/JPR.S353357

PMID: 35502404
Sample: RAW264.7 cell
EXPERIMENTAL BIOLOGY AND MEDICINE (2020) IF: 3.139
Exosomes derived from synovial fibroblasts under hypoxia aggravate rheumatoid arthritis by regulating Treg/Th17 balance:

DOI: 10.1177/1535370220934736

Sample: Cell culture medium
Journal of Functional Foods (2017) IF: 3.144
Antitumor and immunomodulatory effects of ginsenoside Rh2 and its octyl ester derivative in H22 tumor-bearing mice

DOI: 10.1016/j.jff.2017.03.013

Sample: Serum
International Journal of Chronic Obstructive Pulmonary Disease (2017) IF: 3.157
Repression of Toll-like receptor-4 by microRNA-149-3p is associated with smoking-related COPD

DOI: 10.2147/COPD.S128031

Sample: Cell culture supernatant
EUROPEAN JOURNAL OF PHARMACOLOGY (2019) IF: 3.17
Pancreastatin inhibitor PSTi8 attenuates hyperinsulinemia induced obesity and inflammation mediated insulin resistance via MAPK/NOX3-JNK pathway

DOI: 10.1016/j.ejphar.2019.172723

PMID: 31586632
Sample: Plasma
EUROPEAN JOURNAL OF PHARMACOLOGY (2019) IF: 3.17
Circular RNA expression profile of liver tissues in an EtOH-induced mouse model of alcoholic hepatitis

DOI: 10.1016/j.ejphar.2019.172642

PMID: 31493407
Sample: Serum,Tissue homogenate
Journal of Functional Foods (2019) IF: 3.197
Anti-fatigue activity of purified anthocyanins prepared from purple passion fruit (P. edulis Sim) epicarp in mice

DOI: 10.1016/j.jff.2019.103725

Sample: Tissue homogenate
DIGESTIVE DISEASES AND SCIENCES (2019) IF: 3.199
Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice

DOI: 10.1007/s10620-019-05969-w

Sample: blood
INFLAMMATION (2020) IF: 3.212
miR-128-3p Inhibits NRP1 Expression and Promotes Inflammatory Response to Acute Kidney Injury in Sepsis

DOI: 10.1007/s10753-020-01251-8

Sample: TCMK-1 cell
INFLAMMATION (2020) IF: 3.212
Casticin Attenuates Osteoarthritis-Related Cartilage Degeneration by Inhibiting the ROS-Mediated NF-κB Signaling Pathway in vitro and in vivo

DOI: 10.1007/s10753-019-01167-y

Sample: serum,ADTC5 cell
ACTA PHARMACOLOGICA SINICA (2017) IF: 3.223
Molecular mechanisms of the analgesic action of Wu-tou Decoction on neuropathic pain in mice revealed using microarray and network analysis

DOI: 10.1038/aps.2017.110

Sample: Tissue homogenate
Cardiovascular Toxicology (2021) IF: 3.239
Diet-Derived Advanced Glycation End Products (dAGEs) Induce Proinflammatory Cytokine Expression in Cardiac and Renal Tissues of Experimental Mice: Protective Effect of Curcumin

DOI: 10.1007/s12012-021-09697-4

PMID: 34655413
Sample: serum
Food & Function (2019) IF: 3.241
Propacin, a coumarinolignoid isolated from durian, inhibits the lipopolysaccharide-induced inflammatory response in macrophages through the MAPK and NF-κB pathways

DOI: 10.1039/C9FO02202C

PMID: 31859327
Sample: Cell culture supernatant
IUBMB LIFE (2020) IF: 3.244
Blockade of high mobility group box 1 involved in the protective of curcumin on myocardial injury in diabetes in vivo and in vitro

DOI: 10.1002/iub.2226

PMID: 31909882
Sample: Serum
Food & Function (2017) IF: 3.247
Purification, characterization and bioactivities of polysaccharides from Pleurotus ferulae

DOI: 10.1039/C7FO00227K

Sample: Cell culture supernatant
EUROPEAN JOURNAL OF PHARMACOLOGY (2020) IF: 3.263
Pancreastatin inhibitor PSTi8 protects the obesity associated skeletal muscle insulin resistance in diet induced streptozotocin-treated diabetic mice

DOI: 10.1016/j.ejphar.2020.173204

Sample: plasma
MOLECULES (2020) IF: 3.267
Inhibitory Effects of Raw-Extract Centella asiatica (RECA) on Acetylcholinesterase, Inflammations, and Oxidative Stress Activities via In Vitro and In Vivo

DOI: 10.3390/molecules25040892

Sample: RAW 264.7
MOLECULES (2020) IF: 3.267
Anti-Inflammatory Effect of Simonsinol on Lipopolysaccharide Stimulated RAW264.7 Cells through Inactivation of NF-κB Signaling Pathway

DOI: 10.3390/molecules25163573

PMID: 32781605
Sample: Cell culture supernatant
Bioengineered (2021) IF: 3.269
Synergetic protective effect of berberine and ginsenoside Rb1 against tumor necrosis factor alpha−induced inflammation in adipocytes

DOI: 10.1080/21655979.2021.1996508

Sample: 3T3-L1 preadipocyte
Bioengineered (2022) IF: 3.269
Shikonin combined with methotrexate regulate macrophage polarization to treat psoriasis

DOI: 10.1080/21655979.2022.2062090

PMID: 35485255
Sample: RAW264.7 cell
Bioengineered (2021) IF: 3.269
Protective effect of dexmedetomidine in cecal ligation perforation-induced acute lung injury through HMGB1/RAGE pathway regulation and pyroptosis activation

DOI: 10.1080/21655979.2021.2000723

PMID: 34747306
Sample: bronchoalveolar lavage fluid (BALF)
Bioengineered (2022) IF: 3.269
Guizhi Fuling pill attenuates liver fibrosis in vitro and in vivo via inhibiting TGF-β1/Smad2/3 and activating IFN-γ/Smad7 signaling pathways

DOI: 10.1080/21655979.2022.2054224

PMID: 35387552
Sample: liver tissue
Bioengineered (2021) IF: 3.269
Cabergoline possesses a beneficial effect on blood-brain barrier (BBB) integrity against lipopolysaccharide (LPS)

DOI: 10.1080/21655979.2021.1987066

PMID: 34592907
Sample: brain tissue
NEUROSCIENCE (2017) IF: 3.277
Blocking the CD38/cADPR pathway plays a double-edged role in LPS stimulated microglia

DOI: 10.1016/j.neuroscience.2017.08.010

Sample: Cell culture supernatant
VETERINARY MICROBIOLOGY (2022) IF: 3.293
IL-5 enhances the resistance of Actinobacillus pleuropneumoniae infection in mice through maintaining appropriate levels of lung M2, PMN-II and highly effective neutrophil extracellular traps

DOI: 10.1016/j.vetmic.2022.109438

PMID: 35468400
Sample: Bronchoalveolar lavage fluid (BALF)
CELL CYCLE (2018) IF: 3.304
MicroRNA-27a alleviates LPS-induced acute lung injury in mice via inhibiting inﬂammation and apoptosis through modulating TLR4/MyD88/NF-κB pathway

DOI: 10.1080/15384101.2018.1509635

Sample: bronchoalveolar lavage fluid (BALF),RAW 264.7 cell
Diabetes Metabolic Syndrome and Obesity-Targets and Therapy (2019) IF: 3.319
2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione isolated from Averrhoa carambola L. root ameliorates diabetic nephropathy by inhibiting the TLR4/MyD88/NF-κB pathway

DOI: 10.2147/DMSO.S209436

Sample: kidney
INTERNATIONAL IMMUNOPHARMACOLOGY (2019) IF: 3.361
Regulation of CD39 expression in ATP-P2Y2R-mediated alcoholic liver steatosis and inflammation

DOI: 10.1016/j.intimp.2019.105915

PMID: 31639617
Sample: Serum,Cell culture supernatant
CELLULAR & MOLECULAR BIOLOGY LETTERS (2019) IF: 3.367
Tetrahydroxy stilbene glucoside alleviates palmitic acid-induced inflammation and apoptosis in cardiomyocytes by regulating miR-129-3p/Smad3 signaling

DOI: 10.1186/s11658-018-0125-x

PMID: 30820195
Sample: Cell culture supernatant
CELLULAR & MOLECULAR BIOLOGY LETTERS (2019) IF: 3.367
Honokiol alleviates sepsis-induced acute kidney injury in mice by targeting the miR-218-5p/heme oxygenase-1 signaling pathway

DOI: 10.1186/s11658-019-0142-4

PMID: 30833971
Sample: Serum
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2015) IF: 3.369
Dendritic cells enhance UHMWPE wear particle‐induced osteoclast differentiation of macrophages

DOI: 10.1002/jbm.a.35459

Sample: Cell culture supernatant
BRAIN RESEARCH BULLETIN (2020) IF: 3.37
Biological evaluation of naturally occurring bulbocodin D as a potential multi-target agent for Alzheimer’s disease

DOI: 10.1016/j.brainresbull.2020.09.017

Sample: Cell culture supernatant
American Journal of Translational Research (2020) IF: 3.375
Overexpression of lncRNA Gm43050 alleviates apoptosis and inflammation response induced by sevoflurane treatment by regulating miR-640/ZFP91

PMID: 32913509
Sample: primary hippocampal neurons
JOURNAL OF DRUG TARGETING (2020) IF: 3.38
Development, optimisation and evaluation of chitosan nanoparticles of alendronate against Alzheimer’s disease in intracerebroventricular streptozotocin model for brain delivery

DOI: 10.1080/1061186X.2020.1817041

Sample: Tissue homogenate
PPAR Research (2018) IF: 3.386
Portulaca Extract Attenuates Development of Dextran Sulfate Sodium Induced Colitis in Mice through Activation of PPARγ

DOI: 10.1155/2018/6079101

Sample: serum
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2018) IF: 3.388
Aspergillus fumigatus Increased PAR-2 Expression and Elevated Proinflammatory Cytokines Expression Through the Pathway of PAR-2/ERK1/2 in Cornea

DOI: 10.1167/iovs.17-21887

PMID: 29332129
Sample: Tissue homogenate
MOLECULAR AND CELLULAR BIOCHEMISTRY (2020) IF: 3.396
Curcumin amends Ca 2+ dysregulation in microglia by suppressing the activation of P2X7 receptor

DOI: 10.1007/s11010-019-03668-8

Sample: brain,serum
Brain and Behavior (2022) IF: 3.405
MiR-340-5p alleviates neuroinflammation and neuronal injury via suppressing STING in subarachnoid hemorrhage

DOI: 10.1002/brb3.2687

PMID: 35957622
Sample: brain tissue,microglia
Biomed Research International (2021) IF: 3.411
VX765, a Specific Caspase-1 Inhibitor, Alleviates Lung Ischemia Reperfusion Injury by Suppressing Endothelial Pyroptosis and Barrier Dysfunction

DOI: 10.1155/2021/4525988

PMID: 34977239
Sample: lung tissue,serum,PMVEC
Biomed Research International (2022) IF: 3.411
Role of TRPV4 in the Diagnosis and Treatment of Helicobacter pylori Infection in Children with Duodenal Ulcers

DOI: 10.1155/2022/2777882

PMID: 35028313
Sample: serum,duodenal tissue
Biomed Research International (2021) IF: 3.411
Protective Effect of Luteolin on D-Galactosamine (D-Gal)/Lipopolysaccharide (LPS) Induced Hepatic Injury by in Mice

DOI: 10.1155/2021/2252705

PMID: 34368345
Sample: serum,liver
Biomed Research International (2020) IF: 3.411
Irisin Pretreatment Protects Kidneys against Acute Kidney Injury Induced by Ischemia/Reperfusion via Upregulating the Expression of Uncoupling Protein 2

DOI: 10.1155/2020/6537371

PMID: 32934963
Sample: Tissue homogenate
PSYCHOPHARMACOLOGY (2019) IF: 3.424
The protective effect of Geniposide on diabetic cognitive impairment through BTK/TLR4/NF-κB pathway

DOI: 10.1007/s00213-019-05379-w

PMID: 31811349
Sample: Serum
LIFE SCIENCES (2019) IF: 3.448
GPR 30 reduces myocardial infarct area and fibrosis in female ovariectomized mice by activating the PI3K/AKT pathway

DOI: 10.1016/j.lfs.2019.03.049

PMID: 30905784
Sample: Serum
JOURNAL OF CELLULAR BIOCHEMISTRY (2019) IF: 3.448
Attractylone attenuates sepsis‐associated encephalopathy and cognitive dysfunction by inhibiting microglial activation and neuroinflammation

DOI: 10.1002/jcb.27983

Sample: Cell culture supernatant,Tissue homogenate
BIOMEDICINE & PHARMACOTHERAPY (2018) IF: 3.457
The protective effect of formononetin on cognitive impairment in streptozotocin (STZ)-induced diabetic mice

DOI: 10.1016/j.biopha.2018.07.063

Sample: Serum,Tissue homogenate
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2020) IF: 3.47
Honokiol Reduces Fungal Load, Toll-Like Receptor-2, and Inflammatory Cytokines in Aspergillus fumigatus Keratitis

DOI: 10.1167/iovs.61.4.48

PMID: 32347916
Sample: Cell culture supernatant
RSC Medicinal Chemistry (2022) IF: 3.47
Design and synthesis of bile acid derivatives and its activity against colon cancer

DOI: 10.1039/D2MD00220E

Sample: RAW264.7 cell
JOURNAL OF ORTHOPAEDIC RESEARCH (2020) IF: 3.494
Curcumin prevents osteocyte apoptosis by inhibiting M1‐type macrophage polarization in mice model of glucocorticoid‐associated osteonecrosis of the femoral head

DOI: 10.1002/jor.24619

Sample: peripheral blood
TOXICOLOGY IN VITRO (2021) IF: 3.5
(3α)-3-(tiglinoyloxy)-ent-kaur-16-en-19-oic acid, isolated from Wedelia trilobata L., exerts an anti-inflammatory effect via the modulation of NF-κB, MAPK and mTOR pathway and autophagy in LPS-stimulated macrophages

DOI: 10.1016/j.tiv.2021.105139

PMID: 33705895
Sample: Cell culture supernatant
ACS Omega (2022) IF: 3.512
Macrophage Distribution Affected by Virus-Encoded Granulocyte Macrophage Colony Stimulating Factor Combined with Lactate Oxidase

DOI: 10.1021/acsomega.2c03213

PMID: 35847295
Sample: RAW264.7 cell
ACS Omega (2021) IF: 3.512
Curcumin Reduces Cognitive Deficits by Inhibiting Neuroinflammation through the Endoplasmic Reticulum Stress Pathway in Apolipoprotein E4 Transgenic Mice

DOI: 10.1021/acsomega.0c04810

PMID: 33748578
Sample: Tissue homogenate(Brain)
PHOTOCHEMISTRY AND PHOTOBIOLOGY (2023) IF: 3.521
Dendrobium Nobile Lindl Polysaccharides Attenuate UVB-Induced Photodamage by Regulating Oxidative Stress, Inflammation and Mmps Expression in Mice Model

DOI: 10.1111/php.13780

Sample: skin
TOXICOLOGY (2019) IF: 3.547
4-Methylcoumarin-[5,6–g]-hesperetin attenuates inflammatory responses in alcoholic hepatitis through PPAR-γ activation

DOI: 10.1016/j.tox.2019.04.004

PMID: 30951781
Sample: Serum,Cell culture supernatant
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2018) IF: 3.563
Curcumin restrains hepatic glucose production by blocking cAMP/PKA signaling and reducing acetyl CoA accumulation in high-fat diet (HFD)-fed mice

DOI: 10.1016/j.mce.2018.02.018

Sample: liver
TOXICOLOGY LETTERS (2020) IF: 3.569
Methamphetamine induced neuroinflammation in mouse brain and microglial cell line BV2: Roles of the TLR4/TRIF/Peli1 signaling axis

DOI: 10.1016/j.toxlet.2020.07.028

PMID: 32768653
Sample: Cell culture supernatant,Tissue homogenate
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022) IF: 3.575
Sulforaphane protects myocardium from ischemia-reperfusion injury by regulating CaMKIIN2 and CaMKIIδ

DOI: 10.1016/j.bbrc.2022.03.015

PMID: 35316762
Sample: H9c2 cell
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022) IF: 3.575
Loss of serine/threonine protein kinase 25 in retinal ganglion cells ameliorates high glucose-elicited damage through regulation of the AKT-GSK-3β/Nrf2 pathway

DOI: 10.1016/j.bbrc.2022.02.044

PMID: 35217361
Sample: retina ganglion cell
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021) IF: 3.575
Arbutin protects brain against middle cerebral artery occlusion-reperfusion (MCAo/R) injury

DOI: 10.1016/j.bbrc.2021.09.006

PMID: 34507065
Sample: brain
NEUROSCIENCE (2022) IF: 3.59
Pharmacological Postconditioning by Protocatechuic Acid Attenuates Brain Injury in Ischemia–Reperfusion (I/R) Mice Model: Implications of Nuclear Factor Erythroid-2-Related Factor Pathway

DOI: 10.1016/j.neuroscience.2022.03.016

Sample: brain
BMC IMMUNOLOGY (2022) IF: 3.594
NLRP3 inflammasome up-regulates major histocompatibility complex class I expression and promotes inflammatory infiltration in polymyositis

DOI: 10.1186/s12865-022-00515-2

PMID: 35965334
Sample: Raw 264.7 cell
TOXICOLOGY AND APPLIED PHARMACOLOGY (2018) IF: 3.616
SIRT1 activation by butein attenuates sepsis-induced brain injury in mice subjected to cecal ligation and puncture via alleviating inflammatory and oxidative stress

DOI: 10.1016/j.taap.2018.10.013

PMID: 30336174
Sample: Serum,Tissue homogenate
CLINICAL BIOCHEMISTRY (2022) IF: 3.625
Expression of Nrf2 protein in serum of patients with rheumatoid arthritis: A novel indicator for disease activity and disease prognosis

DOI: 10.1016/j.clinbiochem.2022.12.011

Sample: serum
Frontiers in Endocrinology (2020) IF: 3.644
The Protective Effects of Melatonin Against LPS-Induced Septic Myocardial Injury: A Potential Role of AMPK-Mediated Autophagy

DOI: 10.3389/fendo.2020.00162

PMID: 32373063
Sample: Serum
LIFE SCIENCES (2020) IF: 3.647
Effects of taraxasterol against ethanol and high-fat diet-induced liver injury by regulating TLR4/MyD88/NF-κB and Nrf2/HO-1 signaling pathways

DOI: 10.1016/j.lfs.2020.118546

PMID: 33035580
Sample: Serum
LIFE SCIENCES (2020) IF: 3.647
DHCR24 overexpression modulates microglia polarization and inflammatory response via Akt/GSK3β signaling in Aβ25–35 treated BV-2 cells

DOI: 10.1016/j.lfs.2020.118470

Sample: Cell sample
Food & Nutrition Research (2020) IF: 3.647
Camellia cake extracts reduce burn injury through suppressing inflammatory responses and enhancing collagen synthesis

DOI: 10.29219/fnr.v64.3782

PMID: 32425739
Sample: Tissue homogenate
JOURNAL OF FOOD BIOCHEMISTRY (2022) IF: 3.654
Exploring the potential of Lacticaseibacillus paracasei M11 on antidiabetic, anti-inflammatory, and ACE inhibitory effects of fermented dromedary camel milk (Camelus dromedaries) and the release of antidiabetic and anti-hypertensive peptides

DOI: 10.1111/jfbc.14449

PMID: 36206543
Sample: RAW 264.7 cells
METABOLIC BRAIN DISEASE (2022) IF: 3.655
CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen–glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway

DOI: 10.1007/s11011-022-01043-z

Sample: HT22 neurons
GENE (2019) IF: 3.688
The inhibition of microRNA-203 on ischemic reperfusion injury after total knee arthroplasty via suppressing MYD88-mdiated toll-like receptor signaling pathway

DOI: 10.1016/j.gene.2019.02.030

PMID: 30772517
Sample: Tissue homogenate
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2023) IF: 3.688
Artesunate alleviates intracerebral hemorrhage secondary injury by inducing ferroptosis in M1-polarized microglia and suppressing inflammation through AMPK/mTORC1/GPX4 pathway

DOI: 10.1111/bcpt.13848

Sample: brain tissues
JOURNAL OF ETHNOPHARMACOLOGY (2020) IF: 3.69
Discovery of the active compounds of Smilacis Glabrae Rhizoma by utilizing the relationship between the individual differences in blood drug concentration and the pharmacological effect in rats

DOI: 10.1016/j.jep.2020.112886

Sample: RAW 264.7 cell
Journal of Functional Foods (2020) IF: 3.701
Comparison of the structural characteristics and immunostimulatory activities of polysaccharides from wild and cultivated Pleurotus feruleus

DOI: 10.1016/j.jff.2020.104050

Sample: serum
Biomedical Materials (2021) IF: 3.715
The osteoimmunomodulatory effect of nanostructured TiF x /TiO x coating on osteogenesis induction

DOI: 10.1088/1748-605X/ac0863

Sample: RAW264.7 cells
BIOLOGICAL TRACE ELEMENT RESEARCH (2021) IF: 3.738
Sodium P-aminosalicylic Acid Attenuates Manganese-Induced Neuroinflammation in BV2 Microglia by Modulating NF-κB Pathway

DOI: 10.1007/s12011-021-02581-w

PMID: 33447908
Sample: Cell culture supernatant(BV2 Cells)
BIOLOGICAL TRACE ELEMENT RESEARCH (2021) IF: 3.738
Borate Ameliorates Sodium Nitrite-Induced Oxidative Stress Through Regulation of Oxidant/Antioxidant Status: Involvement of the Nrf2/HO-1 and NF-κB Pathways

DOI: 10.1007/s12011-021-02613-5

PMID: 33559025
Sample: Serum
BIOMEDICINE & PHARMACOTHERAPY (2019) IF: 3.743
Combination of tanshinone IIA and astragaloside IV attenuate atherosclerotic plaque vulnerability in ApoE(-/-) mice by activating PI3K/AKT signaling and suppressing TRL4/NF-κB signaling

DOI: 10.1016/j.biopha.2019.109729

Sample: plasma,RAW264.7 cell
BIOMEDICINE & PHARMACOTHERAPY (2019) IF: 3.743
Antidiarrheal effects of a thermostable protein fraction obtained from the larvae of Musca domestica

DOI: 10.1016/j.biopha.2019.108813

Sample: RAW 264.7 cells
Marine Drugs (2019) IF: 3.772
Pepsin-Soluble Collagen from the Skin of Lophius litulo: A Preliminary Study Evaluating Physicochemical, Antioxidant, and Wound Healing Properties

DOI: 10.3390/md17120708

Sample: serum
Heliyon (2022) IF: 3.776
A sesquiterpene isolated from the stems and leaves of Dioscorea opposita thunb. Transforms the composition of immune cells through ERβ in a mouse model of LPS-induced lung injury

DOI: 10.1016/j.heliyon.2022.e10500

Sample: Serum,lung tissue,BEAS-2B cell
JOURNAL OF NATURAL PRODUCTS (2020) IF: 3.782
3α-Angeloyloxy-ent-kaur-16-en-19-oic Acid Isolated from Wedelia trilobata L. Alleviates Xylene-Induced Mouse Ear Edema and Inhibits NF-κB and MAPK Pathway in LPS-Stimulated Macrophages

DOI: 10.1021/acs.jnatprod.0c00990

Sample: Cell culture medium,Tissue Slice
SURFACE & COATINGS TECHNOLOGY (2020) IF: 3.784
In vitro and in vivo biocompatibility study of surface modified TiN deposited on Ti6Al4V using high-power impulse magnetron sputtering technique

DOI: 10.1016/j.surfcoat.2020.125814

Sample: skin
MICROBIAL PATHOGENESIS (2022) IF: 3.848
Effect of Enterococcus faecalis on osteoclastogenesis under cobalt-mimicked hypoxia in vitro

DOI: 10.1016/j.micpath.2022.105964

Sample: bone marrow-derived macrophages (BMMs)
PEPTIDES (2022) IF: 3.867
Pancreastatin inhibitor PSTi8 balances energy homeostasis by attenuating adipose tissue inflammation in high fat diet fed mice

DOI: 10.1016/j.peptides.2022.170902

Sample: serum
NEUROCHEMISTRY INTERNATIONAL (2020) IF: 3.881
Hesperidin alleviates chronic restraint stress and lipopolysaccharide-induced Hippocampus and Frontal cortex damage in mice: Role of TLR4/NF-κB, p38 MAPK/JNK, Nrf2/ARE signaling

DOI: 10.1016/j.neuint.2020.104835

PMID: 32853749
Sample: Serum
Food & Nutrition Research (2021) IF: 3.894
Effects of different doses of omega-3 polyunsaturated fatty acids on gut microbiota and immunity

DOI: 10.29219/fnr.v65.6263

PMID: 34349613
Sample: serum
Frontiers in Medicine (2020) IF: 3.9
Adiponectin Inhibits NLRP3 Inflammasome Activation in Nonalcoholic Steatohepatitis via AMPK-JNK/ErK1/2-NFκB/ROS Signaling Pathways

DOI: 10.3389/fmed.2020.546445

PMID: 33251225
Sample: Tissue homogenate(liver tissue)
JOURNAL OF CELLULAR PHYSIOLOGY (2018) IF: 3.923
Blocking PI3K/AKT signaling inhibits bone sclerosis in subchondral bone and attenuates post‐traumatic osteoarthritis

DOI: 10.1002/jcp.26460

Sample: serum,preosteoblasts
RESPIRATORY RESEARCH (2020) IF: 3.924
Thymosin β10 promotes tumor-associated macrophages M2 conversion and proliferation via the PI3K/Akt pathway in lung adenocarcinoma

DOI: 10.1186/s12931-020-01587-7

Sample: RAW264.7 cell
BIOORGANIC CHEMISTRY (2018) IF: 3.929
Assessment of novel azaanthraquinone derivatives as potent multi-target inhibitors of inflammation and amyloid-β aggregation in Alzheimer’s disease

DOI: 10.1016/j.bioorg.2018.10.073

Sample: Cell culture medium
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
Saikosaponin-d attenuated lipopolysaccharide-induced depressive-like behaviors via inhibiting microglia activation and neuroinflammation

DOI: 10.1016/j.intimp.2019.106181

PMID: 31926446
Sample: Cell sample,Tissue homogenate
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
NLRP12 negatively regulates EtOH-induced liver macrophage activation via NF-κB pathway and mediates hepatocyte apoptosis in alcoholic liver injury

DOI: 10.1016/j.intimp.2020.106968

PMID: 33182058
Sample: serum,RAW 264.7 cell
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
Myricitrin pretreatment ameliorates mouse liver ischemia reperfusion injury

DOI: 10.1016/j.intimp.2020.107005

PMID: 33045574
Sample: Serum
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
Molecular hydrogen attenuates sepsis-induced neuroinflammation through regulation of microglia polarization through an mTOR-autophagy-dependent pathway

DOI: 10.1016/j.intimp.2020.106287

PMID: 32058932
Sample: Tissue homogenate
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
miR-129-5p alleviates LPS-induced acute kidney injury via targeting HMGB1/TLRs/NF-kappaB pathway

DOI: 10.1016/j.intimp.2020.107016

PMID: 33039954
Sample: Serum
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
Inhibition of HMGB1 involved in the protective of salidroside on liver injury in diabetes mice

DOI: 10.1016/j.intimp.2020.106987

PMID: 33217691
Sample: Cell culture supernatant,Serum,Tissue homogenate
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice

DOI: 10.1016/j.intimp.2020.107003

PMID: 33182043
Sample: Tissue homogenate
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
Betulin alleviates on myocardial inflammation in diabetes mice via regulating Siti1/NLRP3/NF-κB pathway

DOI: 10.1016/j.intimp.2020.106653

Sample: serum,heart
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
4-hydroxybenzo[d]oxazol-2(3H)-one ameliorates LPS/D-GalN-induced acute liver injury by inhibiting TLR4/NF-κB and MAPK signaling pathways in mice

DOI: 10.1016/j.intimp.2020.106445

PMID: 32272395
Sample: Tissue homogenate
INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells

DOI: 10.1016/j.intimp.2020.106501

Sample: Cell culture supernatant
CARDIOVASCULAR DRUGS AND THERAPY (2022) IF: 3.947
Sulfated Galactofucan from Sargassum Thunbergii Attenuates Atherosclerosis by Suppressing Inflammation Via the TLR4/MyD88/NF-κB Signaling Pathway

DOI: 10.1007/s10557-022-07383-3

PMID: 36194354
Sample: serum,RAW264.7 cells
NEUROTOXICITY RESEARCH (2022) IF: 3.978
Polydatin Prevents Neuroinflammation and Relieves Depression via Regulating Sirt1/HMGB1/NF-κB Signaling in Mice

DOI: 10.1007/s12640-022-00553-z

PMID: 35986876
Sample: Brain tissue
NEUROCHEMICAL RESEARCH (2021) IF: 3.996
Platinum nanoparticles Protect Against Lipopolysaccharide-Induced Inflammation in Microglial BV-2 Cells via Decreased Oxidative Damage and Increased Phagocytosis

DOI: 10.1007/s11064-021-03434-7

PMID: 34432181
Sample: BV-2 cell
Scientific Reports (2020) IF: 3.998
Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-κB pathway

DOI: 10.1038/s41598-020-66789-x

PMID: 32555320
Sample: Serum
PARASITOLOGY RESEARCH (2016) IF: 2.027
spp. in experimentally infected immunocompetent and immunosuppresed mice

DOI: 10.1007/s00436-016-4951-3

Sample: Serum,Tissue homogenate
POULTRY SCIENCE (2019) IF: 2.027
Anti-inflammatory effect of preserved egg with simulated gastrointestinal digestion on LPS-stimulated RAW264.7 cells

DOI: 10.3382/ps/pez243

PMID: 31041437
Sample: Cell culture supernatant
MEDICINE (2018) IF: 2.028
Effect of gap junctions on RAW264.7 macrophages infected with H37Rv

DOI: 10.1097/MD.0000000000012125

Sample: Cell culture supernatant
MOLECULAR DIVERSITY (2019) IF: 2.032
Hybrids of oxoisoaporphine–tetrahydroisoquinoline: novel multi-target inhibitors of inflammation and amyloid-β aggregation in Alzheimer’s disease

DOI: 10.1007/s11030-018-9905-5

Sample: Cell culture medium
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2019) IF: 2.041
Role of Brd4 in the production of inflammatory cytokines in mouse macrophages treated with titanium particles

DOI: 10.1139/cjpp-2019-0142

PMID: 31330113
Sample: Cell culture supernatant
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2019) IF: 2.058
Antihypernociceptive and neuroprotective effects of Combretin A and Combretin B on streptozotocin-induced diabetic neuropathy in mice

DOI: 10.1007/s00210-019-01626-1

PMID: 30759263
Sample: Serum,Spinal cord
Brain and Behavior (2020) IF: 2.091
MicroRNA‐345‐5p regulates depression by targeting suppressor of cytokine signaling 1

DOI: 10.1002/brb3.1653

Sample: Cell culture supernatant
Molecular Medicine Reports (2020) IF: 2.1
Osthole inhibits proliferation of kainic acid‑activated BV‑2 cells by modulating the Notch signaling pathway

DOI: 10.3892/mmr.2020.11455

PMID: 33000274
Sample: Cell culture supernatant
Molecular Medicine Reports (2020) IF: 2.1
Coenzyme Q10 alleviates sevoflurane‑induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons

DOI: 10.3892/mmr.2020.11131

Sample: Tissue homogenate
Current Medical Science (2019) IF: 2.135
Berberine Attenuates Cigarette Smoke Extract-induced Airway Inflammation in Mice: Involvement of TGF-β1/Smads Signaling Pathway

DOI: 10.1007/s11596-019-2101-8

PMID: 31612392
Sample: Bronchoalveolar Lavage Fluid
STEROIDS (2019) IF: 2.136
Synthesis and evaluation of novel D-ring substituted steroidal pyrazolines as potential anti-inflammatory agents

DOI: 10.1016/j.steroids.2019.03.012

PMID: 30951758
Sample: Cell culture supernatant
International Journal of Peptide Research and Therapeutics (2022) IF: 2.191
Atrial Natriuretic Peptide (ANP) Suppress λ-Carrageenan-Induced Acute Paw Edema by Modulating Pro-inflammatory Genes in Swiss Albino Mice

DOI: 10.1007/s10989-022-10444-8

Sample: paw tissue
JOURNAL OF NEUROSCIENCE METHODS (2020) IF: 2.214
Frequent exposure to varied home cage sizes alters pain sensitivity and some key inflammation-related biomarkers

DOI: 10.1016/j.jneumeth.2020.108890

PMID: 32768413
Sample: Tissue homogenate
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015) IF: 2.297
Ghrelin ameliorates intestinal barrier dysfunction in experimental colitis by inhibiting the activation of nuclear factor-kappa B

DOI: 10.1016/j.bbrc.2015.01.083

Sample: Tissue homogenate
HISTOLOGY AND HISTOPATHOLOGY (2021) IF: 2.303
Death-associated protein kinase 1 correlates with podocyte apoptosis and renal damage and can be mediated by miR-361.

DOI: 10.14670/hh-18-358

Sample: renal podocytes
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2020) IF: 2.352
Kupffer cell inactivation ameliorates immune liver injury via TNF-α/TNFR1 signal pathway in trichloroethylene sensitized mice

DOI: 10.1080/08923973.2020.1811306

PMID: 32811237
Sample: Serum
PeerJ (2020) IF: 2.379
The immunostimulatory activity of polysaccharides from Glycyrrhiza uralensis

DOI: 10.7717/peerj.8294

PMID: 32030319
Sample: Tissue homogenate
PARASITOLOGY RESEARCH (2022) IF: 2.383
Plasmodium knowlesi Duffy binding protein alpha region II (PkDBPαII) in clinical isolates from Peninsular Malaysia and Malaysian Borneo exhibit different immune responses in animal models

DOI: 10.1007/s00436-022-07665-7

PMID: 36152079
Sample: Spleen cell
CHEMISTRY & BIODIVERSITY (2021) IF: 2.408
Protective Effect of n-Butanol Extract from Viola yedoensis on Immunological Liver Injury

DOI: 10.1002/cbdv.202001043

PMID: 33929783
Sample: Tissue homogenate(liver)
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2019) IF: 2.422
Effect and mechanism of citral against methicillin‐resistant Staphylococcus aureus in vivo

DOI: 10.1002/jsfa.9677

Sample: Serum
Psychogeriatrics (2021) IF: 2.44
HMGB1 augments cognitive impairment in sepsis-associated encephalopathy by binding to MD-2 and promoting NLRP3-induced neuroinflammation

DOI: 10.1111/psyg.12794

PMID: 34931753
Sample: brain,serum
METABOLIC BRAIN DISEASE (2018) IF: 2.441
Gentiopicroside abrogates lipopolysaccharide-induced depressive-like behavior in mice through tryptophan-degrading pathway

DOI: 10.1007/s11011-018-0246-y

Sample: Plasma
Experimental and Therapeutic Medicine (2021) IF: 2.447
IL‑17 promotes proliferation, inflammation and inhibits apoptosis of HaCaT cells via interacting with the TRAF3 interacting protein 2

DOI: 10.3892/etm.2020.9480

Sample: Cell culture supernatant
Experimental and Therapeutic Medicine (2017) IF: 2.447
Effects of sepsis on the metabolism of sphingomyelin and cholesterol in mice with liver dysfunction

DOI: 10.3892/etm.2017.5226

Sample: Plasma
Experimental and Therapeutic Medicine (2020) IF: 2.447
Clostridium butyricum protects intestinal barrier function via upregulation of tight junction proteins and activation of the Akt/mTOR signaling pathway in a mouse model of dextran sodium sulfate‑induced colitis

DOI: 10.3892/etm.2020.9138

Sample: Serum
Experimental and Therapeutic Medicine (2020) IF: 2.447
Clostridium butyricum protects intestinal barrier function via upregulation of tight junction proteins and activation of the Akt/mTOR signaling pathway in a mouse model of dextran sodium sulfate‑induced colitis

DOI: 10.3892/etm.2020.9138

Sample: Serum
NEUROLOGICAL RESEARCH (2020) IF: 2.451
The intervention mechanism of emodin on TLR3 pathway in the process of central nervous system injury caused by herpes virus infection

DOI: 10.1080/01616412.2020.1853989

PMID: 33274693
Sample: Tissue homogenate
TISSUE & CELL (2022) IF: 2.466
Upregulation of BRD7 protects podocytes against high glucose-induced apoptosis by enhancing Nrf2 in a GSK-3β-dependent manner

DOI: 10.1016/j.tice.2022.101813

PMID: 35550209
Sample: MPC-5 cell
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2020) IF: 2.477
Isolation, characterization and anti-inflammatory mechanism of probiotics in lipopolysaccharide-stimulated RAW 264.7 macrophages

DOI: 10.1007/s11274-020-02852-z

Sample: RAW 264.7 cell
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2022) IF: 2.557
Dihydroartemisinin protects blood-brain barrier permeability during sepsis by inhibiting the transcription factor SNAI1

DOI: 10.1111/1440-1681.13683

PMID: 35651290
Sample: serum,cortex
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018) IF: 2.559
Eosinophils attenuate arthritis by inducing M2 macrophage polarization via inhibiting the IκB/P38 MAPK signaling pathway

DOI: 10.1016/j.bbrc.2018.12.010

Sample: Tissue homogenate,Cell culture supernatant
JOURNAL OF PHARMACY AND PHARMACOLOGY (2020) IF: 2.571
Therapeutic effects of Qianlie Tongli decoction on chronic prostatitis/chronic pelvic pain syndrome induced by peptide T2 in mice

DOI: 10.1111/jphp.13325

PMID: 32648958
Sample: Plasma
MICROBIAL PATHOGENESIS (2019) IF: 2.581
Metabolites of stable fly reduce diarrhea in mice by modulating the immune system, antioxidants, and composition of gut microbiota

DOI: 10.1016/j.micpath.2019.103557

Sample: serum,small intestinal tissues
Biomed Research International (2018) IF: 2.583
Upregulated TSG-6 Expression in ADSCs Inhibits the BV2 Microglia-Mediated Inflammatory Response

DOI: 10.1155/2018/7239181

Sample: BV2 cells
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2019) IF: 2.606
Incorporation of shRNA in bioactive glass coated SS316L implant material and its role in inhibition of the osteoclast activity for better post implantation fixation

DOI: 10.1016/j.jddst.2019.05.031

Sample: RAW 264.7 cells
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2021) IF: 2.607
Anti-Inflammatory and Immunomodulatory Role of Bone Marrow-Derived MSCs in Mice with Acute Lung Injury

DOI: 10.1089/jir.2020.0073

Sample: plasma
Evidence-based Complementary and Alternative Medicine (2022) IF: 2.63
Camelina sativa Oil Treatment Alleviates Castor Oil-Induced Diarrhea in ICR Mice by Regulating Intestinal Flora Composition

DOI: 10.1155/2022/5394514

PMID: 35178105
Sample: plasma
ARCHIVES OF ORAL BIOLOGY (2023) IF: 2.64
IL-37 alleviates alveolar bone resorption and inflammatory response through the NF-κB/NLRP3 signaling pathway in male mice with periodontitis

DOI: 10.1016/j.archoralbio.2023.105629

Sample: periodontal tissue
Evidence-based Complementary and Alternative Medicine (2022) IF: 2.65
Febuxostat Alleviates Allergic Rhinitis by Inhibiting Inflammation and Monocyte Adhesion in Human Nasal Epithelial Cells via Regulating KLF6.

DOI: 10.1155/2022/9092311

Sample: nasal mucosa tissue
Evidence-based Complementary and Alternative Medicine (2022) IF: 2.65
Exploring the Muscle Metabolomics in the Mouse Model of Sepsis-Induced Acquired Weakness

DOI: 10.1155/2022/6908488

PMID: 36016684
Sample: serum
Evidence-based Complementary and Alternative Medicine (2022) IF: 2.65
Anti-inflammatory Mechanism of Action of Benzoylmesaconine in Lipopolysaccharide-Stimulated RAW264.7 Cells

DOI: 10.1155/2022/7008907

PMID: 35873638
Sample: RAW264.7 cell
STEROIDS (2021) IF: 2.668
Synthesis and anti-inflammatory activity of novel steroidal chalcones with 3β-pregnenolone ester derivatives in RAW 264.7 cells in vitro

DOI: 10.1016/j.steroids.2021.108830

PMID: 33836205
Sample: Cell culture supernatant
Innate Immunity (2021) IF: 2.68
Chrysosplenol D protects mice against LPS-induced acute lung injury by inhibiting oxidative stress, inflammation, and apoptosis via TLR4-MAPKs/NF-κB signaling pathways:

DOI: 10.1177/17534259211051069

Sample: Bronchoalveolar Lavage Fluid
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2020) IF: 2.69
IL-4 functionalized titanium dioxide nanotubes modulate the inflammatory response of macrophages

DOI: 10.1080/09205063.2020.1799534

Sample: RAW264.7 cell
Iranian Journal of Basic Medical Sciences (2021) IF: 2.699
Corilagin potential in inhibiting oxidative and inflammatory stress in LPS-induced murine macrophage cell lines (RAW 264.7)

DOI: 10.22038/IJBMS.2021.59348.13174

Sample: RAW 264.7 cell
PLACENTA (2015) IF: 2.71
The effect of maternal obesity on the expression and functionality of placental P-glycoprotein: Implications in the individualized transplacental digoxin treatment for fetal heart failure

DOI: 10.1016/j.placenta.2015.08.007

Sample: Plasma
JOURNAL OF NEUROPHYSIOLOGY (2022) IF: 2.714
Sesamin inhibits cellular inflammation of microglial cells in the retina and alleviates diabetic retinopathy

DOI: 10.1152/jn.00466.2021

Sample: serum,vitreous body,BV2 cell
JOURNAL OF FOOD BIOCHEMISTRY (2021) IF: 2.72
Buchholzia coriacea seed (wonderful kolanut) alleviates insulin resistance, steatosis, inflammation and oxidative stress in high fat diet model of fatty liver disease

DOI: 10.1111/jfbc.13836

PMID: 34184286
Sample: plasma
JOURNAL OF FOOD BIOCHEMISTRY (2022) IF: 2.72
Broccoli microgreens have hypoglycemic effect by improving blood lipid and inflammatory factors while modulating gut microbiota in mice with type 2 diabetes

DOI: 10.1111/jfbc.14145

PMID: 35348219
Sample: serum
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2022) IF: 2.723
The Berberis vulgaris L. extract berberine exerts its anti-oxidant effects to ameliorate cholesterol overloading–induced cell apoptosis in the primary mice hepatocytes: an in vitro study

DOI: 10.1007/s11626-022-00737-z

Sample: serum
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2022) IF: 2.723
Hace1 overexpression mitigates myocardial hypoxia/reoxygenation injury via the effects on Keap1/Nrf2 pathway

DOI: 10.1007/s11626-022-00725-3

PMID: 36251153
Sample: Primary cardiac cells
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2022) IF: 2.73
Protective effects of endotoxin tolerance on peripheral lipopolysaccharide-induced neuroinflammation and dopaminergic neuronal injury

DOI: 10.1080/08923973.2022.2043900

PMID: 35260024
Sample: substantia nigra (SN)
REDOX REPORT (2020) IF: 2.753
hnRNPK knockdown alleviates NLRP3 inflammasome priming by repressing FLIP expression in Raw264.7 macrophages

DOI: 10.1080/13510002.2020.1857157

PMID: 33269646
Sample: Cell culture supernatant
CNS & Neurological Disorders-Drug Targets (2019) IF: 2.761
Formononetin Ameliorates Cognitive Disorder via PGC-1α Pathway in Neuroinflammation Conditions in High-Fat Diet-Induced Mice

DOI: 10.2174/1871527318666190807160137

Sample: hippocampus
Plants-Basel (2020) IF: 2.762
Phytochemical, Cytotoxicity, Antioxidant and Anti-Inflammatory Effects of Psilocybe Natalensis Magic Mushroom

DOI: 10.3390/plants9091127

PMID: 32878164
Sample: Cell culture supernatant
PLoS One (2018) IF: 2.766
AT1-receptor blockade: Protective effects of irbesartan in cardiomyocytes under hypoxic stress

DOI: 10.1371/journal.pone.0202297

PMID: 30356256
Sample: Cell culture supernatant
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2018) IF: 2.784
miR-124/MCP-1 signaling pathway modulates the protective effect of itraconazole on acute kidney injury in a mouse model of disseminated candidiasis

DOI: 10.3892/ijmm.2018.3564

Sample: serum
BMC Complementary and Alternative Medicine (2020) IF: 2.833
4-Hydroxyisoleucine relieves inflammation through iRhom2-dependent pathway in co-cultured macrophages and adipocytes with LPS stimulation

DOI: 10.1186/s12906-020-03166-1

PMID: 33298044
Sample: Cell sample
Diabetes Metabolic Syndrome and Obesity-Targets and Therapy (2020) IF: 2.842
Isomangiferin Attenuates Renal Injury in Diabetic Mice via Inhibiting Inflammation

DOI: 10.2147/DMSO.S276229

PMID: 33204133
Sample: Serum,Tissue homogenate
MOLECULES (2017) IF: 2.861
Capparis spinosa Fruit Ethanol Extracts Exert Different Effects on the Maturation of Dendritic Cells

DOI: 10.3390/molecules22010097

Sample: Cell culture supernatant
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015) IF: 2.862
Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol

DOI: 10.3390/ijms160922062

Sample: Serum,Tissue homogenate
NATURAL PRODUCT RESEARCH (2021) IF: 2.862
Anti-inflammatory and antioxidant activities of chemical constituents from the flower buds of Buddleja officinalis

DOI: 10.1080/14786419.2021.1952577

PMID: 34498975
Sample: RAW264.7 cell
NEUROBIOLOGY OF LEARNING AND MEMORY (2021) IF: 2.877
GLP-1R activation ameliorated novel-object recognition memory dysfunction via regulating hippocampal AMPK/NF-κB pathway in neuropathic pain mice

DOI: 10.1016/j.nlm.2021.107463

PMID: 34015440
Sample: Tissue homogenate(hippocampus)
CHRONOBIOLOGY INTERNATIONAL (2021) IF: 2.877
Differential response of diurnal and nocturnal mammals to prolonged altered light-dark cycle: a possible role of mood associated endocrine, inflammatory and antioxidant system

DOI: 10.1080/07420528.2021.1937200

PMID: 34128442
Sample: serum,hippocampus
FITOTERAPIA (2021) IF: 2.882
Structure elucidation and anti-inflammatory mechanism of difengpienol C, a new neolignan isolated from Illicium difengpi

DOI: 10.1016/j.fitote.2021.104949

PMID: 34087408
Sample: RAW264.7 cells
INFLAMMATION (2018) IF: 2.884
MiR-590-3p Attenuates Acute Kidney Injury by Inhibiting Tumor Necrosis Factor Receptor-Associated Factor 6 in Septic Mice

DOI: 10.1007/s10753-018-0921-5

PMID: 30392071
Sample: Serum
INFLAMMATION (2018) IF: 2.884
Attenuation of Inflammation and Oxidative Stress in High-Fat-Diet-Induced Obese Mice

DOI: 10.1007/s10753-018-0948-7

Sample: Tissue homogenate
HUMAN & EXPERIMENTAL TOXICOLOGY (2022) IF: 2.903
Neurotoxic 18-kDa apolipoprotein E fragment production contributes to anesthetic sevoflurane-induced tau phosphorylation and neuroinflammation in vitro:

DOI: 10.1177/09603271221102519

Sample: neurons
MICROBIAL PATHOGENESIS (2020) IF: 2.914
Exposure time determines the protective effect of Trichinella spiralis on experimental colitis

DOI: 10.1016/j.micpath.2020.104263

PMID: 32442663
Sample: Serum
MICROBIAL PATHOGENESIS (2020) IF: 2.914
Curcumin ameliorates Staphylococcus aureus-induced mastitis injury through attenuating TLR2-mediated NF−κB activation

DOI: 10.1016/j.micpath.2020.104054

Sample: Serum
RSC Advances (2018) IF: 2.936
Protective effects of SKLB023 on a mouse model of unilateral ureteral obstruction by the modulation of gut microbiota

DOI: 10.1039/C8RA08049F

Sample: plasma
INFLAMMATION (2019) IF: 2.939
Sinomenine Attenuates Cartilage Degeneration by Regulating miR-223-3p/NLRP3 Inflammasome Signaling

DOI: 10.1007/s10753-019-00986-3

PMID: 30847744
Sample: Serum,Cell culture supernatant
INFLAMMATION (2019) IF: 2.939
Effect of Oral T2 Antigen on Chronic Prostatitis/Chronic Pelvic Pain Syndrome in Mice Model

DOI: 10.1007/s10753-019-01072-4

Sample: Serum
BIOSCIENCE REPORTS (2020) IF: 2.942
Atractylon treatment prevents sleep-disordered breathing-induced cognitive dysfunction by suppression of chronic intermittent hypoxia-induced M1 microglial activation

DOI: 10.1042/BSR20192800

PMID: 32490526
Sample: Cell culture supernatant
Molecular Medicine Reports (2020) IF: 2.952
Placenta‑derived mesenchymal stem cells ameliorate lipopolysaccharide‑induced inflammation in RAW264.7 cells and acute lung injury in rats

DOI: 10.3892/mmr.2020.11231

Sample: Cell culture supernatant
Molecular Medicine Reports (2019) IF: 2.952
BCG stimulation promotes dendritic cell proliferation and expression of VDR and CYP27B1 in vitamin D‑deficient mice

DOI: 10.3892/mmr.2019.10780

Sample: BMDCs
Molecular Medicine Reports (2020) IF: 2.952
Astaxanthin suppresses lipopolysaccharide‑induced myocardial injury by regulating MAPK and PI3K/AKT/mTOR/GSK3β signaling

DOI: 10.3892/mmr.2020.11443

PMID: 32945516
Sample: Serum
INTERNATIONAL IMMUNOPHARMACOLOGY (2017) IF: 2.956
Wogonin attenuates inflammation by activating PPAR-γ in alcoholic liver disease

DOI: 10.1016/j.intimp.2017.06.013

Sample: Serum,Cell culture supernatant
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2019) IF: 2.965
Gastrodin attenuates neuroinflammation in DOI‐induce Tourette syndrome in rats

DOI: 10.1002/jbt.22302

Sample: Serum,Tissue homogenate
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2019) IF: 2.965
Gastrodin alleviates Tourette syndrome via Nrf‐2/HO‐1/HMGB1/NF‐кB pathway

DOI: 10.1002/jbt.22389

Sample: Tissue homogenate
PeerJ (2022) IF: 2.984
Quercetin prevents chronic kidney disease on mesangial cells model by regulating inflammation, oxidative stress, and TGF-β1/SMADs pathway

DOI: 10.7717/peerj.13257

PMID: 35673387
Sample: SV40 MES 13 cell
PeerJ (2022) IF: 2.984
3,4-dihydroxyphenylethyl alcohol glycoside reduces acetaminophen-induced acute liver failure in mice by inhibiting hepatocyte ferroptosis and pyroptosis

DOI: 10.7717/peerj.13082

PMID: 35310165
Sample: plasma
TRANSPLANTATION PROCEEDINGS (2022) IF: 1.066
A Novel Hepatectomy Model in Mice Using a Gutta Cutter Tool: A Feasibility Study and Preliminary Results

DOI: 10.1016/j.transproceed.2022.01.029

PMID: 35287968
Sample: serum
GENERAL PHYSIOLOGY AND BIOPHYSICS (2020) IF: 1.07
The TrkB agonist 7,8-dihydroxyflavone improves sensory-motor performance and reduces lipid peroxidation in old mice.

DOI: 10.4149/gpb_2020022

Sample: cortex
BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT (2020) IF: 1.186
Human umbilical cord mesenchymal stem cells suppress lung cancer via TLR4/NF-κB signalling pathway

DOI: 10.1080/13102818.2020.1712257

Sample: Lewis cell-xenograft
International Journal of Ophthalmology (2019) IF: 1.189
Expression and role of calcitonin gene-related peptide in mouse Aspergillus fumigatus keratitis

DOI: 10.18240/ijo.2019.05.01

PMID: 31131225
Sample: Cell culture supernatant
NEUROREPORT (2018) IF: 1.266
Role of receptor-interacting protein 1/receptor-interacting protein 3 in inflammation and necrosis following chronic constriction injury of the sciatic nerve

DOI: 10.1097/WNR.0000000000001120

PMID: 30192300
Sample: Tissue homogenate
NEUROREPORT (2018) IF: 1.266
Gentiopicroside protects neurons from astrocyte-mediated inflammatory injuries by inhibition of nuclear factor-κB and mitogen-activated protein kinase signaling pathways

DOI: 10.1097/WNR.0000000000001082

PMID: 29958245
Sample: Cell culture supernatant
Current Medical Science (2020) IF: 1.273
Role of Interleukin 17A in Aortic Valve Inflammation in Apolipoprotein E-deficient Mice

DOI: 10.1007/s11596-020-2230-0

PMID: 32862384
Sample: Plasma
International Journal of Clinical and Experimental Medicine (2015) IF: 1.277
Sulfated modification promotes the immunomodulatory bioactivities of Lyciumbarbarum polysaccharides in vitro

PMID: 26884954
Sample: lymphocyte
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2020) IF: 1.287
Gallincin ameliorates colitis-associated inflammation and barrier function in mice based on network pharmacology prediction:

DOI: 10.1177/0300060520951023

Sample: homogenized colonic tissue
International Journal of Ophthalmology (2020) IF: 1.33
Anti-inflammatory effects of astaxanthin against fungal keratitis

DOI: 10.18240/ijo.2020.11.01

PMID: 33214996
Sample: Tissue homogenate(Corneas)
JOURNAL OF FOOD BIOCHEMISTRY (2019) IF: 1.358
Immunomodulatory effect of papaya (Carica papaya) pulp and seed extracts as a potential natural treatment for bacterial stress

DOI: 10.1111/jfbc.13050

PMID: 31571245
Sample: Serum
Medical Molecular Morphology (2019) IF: 1.383
The therapeutic effects of resveratrol on hepatic steatosis in high-fat diet-induced obese mice by improving oxidative stress, inflammation and lipid-related gene transcriptional expression

DOI: 10.1007/s00795-019-00216-7

PMID: 30673851
Sample: Serum,Tissue homogenate
International Journal of Clinical and Experimental Pathology (2018) IF: 1.396
An experimental hyperlipidemia model with periodontitis in mice

PMID: 31938106
Sample: serum
JOURNAL OF APPLIED ANIMAL WELFARE SCIENCE (2021) IF: 1.44
Enriched environment during adolescence modulates lipid metabolism and emotion-related behaviors in mice

DOI: 10.1080/10888705.2021.1972421

PMID: 34470518
Sample: serum
AESTHETIC PLASTIC SURGERY (2018) IF: 1.484
Preadipocytes In Vitro

DOI: 10.1007/s00266-018-1294-8

Sample: Cell culture supernatant
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2018) IF: 1.492
NLRP3 inflammasome signaling as an early molecular response is negatively controlled by miR-186 in CFA-induced prosopalgia mice

DOI: 10.1590/1414-431X20187602

Sample: Serum,Tissue homogenate
AEROBIOLOGIA (2018) IF: 1.515
Aerofloral investigation and allergenic potentials of two dominant airborne pollen types at selected sites in South-western Nigeria

DOI: 10.1007/s10453-018-9533-7

Sample: Plasma
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2019) IF: 1.54
Chemerin-9 Peptide Enhances Memory and Ameliorates Aβ1-42-induced Object Memory Impairment in Mice

DOI: 10.1248/bpb.b19-00510

Sample: hippocampus
Oncology Letters (2018) IF: 1.664
The association between inflammation, the microbiome and urethane-induced pulmonary adenocarcinoma Corrigendum in /10.3892/ol.2018.9063

DOI: 10.3892/ol.2018.8167

Sample: Serum
Molecular Medicine Reports (2017) IF: 1.692
Bone marrow mesenchymal stem cells accelerate the hyperglycemic refractory wound healing by inhibiting an excessive inflammatory response

DOI: 10.3892/mmr.2017.6400

Sample: Skin tissue
BMC Pharmacology & Toxicology (2020) IF: 1.771
Impact of Lesinurad and allopurinol on experimental Hyperuricemia in mice: biochemical, molecular and Immunohistochemical study

DOI: 10.1186/s40360-020-0386-7

PMID: 32041665
Sample: Serum
Experimental and Therapeutic Medicine (2020) IF: 1.785
Curcumin affects ox‑LDL‑induced IL‑6, TNF‑α, MCP‑1 secretion and cholesterol efflux in THP‑1 cells by suppressing the TLR4/NF‑κB/miR33a signaling pathway

DOI: 10.3892/etm.2020.8915

Sample: Cell culture supernatant
Evidence-based Complementary and Alternative Medicine (2020) IF: 1.813
Antioxidant and Anti-Inflammatory Activities of Kigelia africana (Lam.) Benth.

DOI: 10.1155/2020/4352084

Sample: RAW 264.7 cell
International Heart Journal (2022) IF: 1.862
Adipose-Derived Stem Cells-Derived Exosomes with High Amounts of Circ_0001747 Alleviate Hypoxia/Reoxygenation-Induced Injury in Myocardial Cells by Targeting MiR-199b-3p/MCL1 Axis

DOI: 10.1536/ihj.21-441

PMID: 35354755
Sample: HL-1 cell
MEDICAL SCIENCE MONITOR (2018) IF: 1.894
Alteration of Circadian Rhythms in 2D2 Transgenic Mice

DOI: 10.12659/MSM.908528

Sample: serum
BIOMEDICAL AND ENVIRONMENTAL SCIENCES (2019) IF: 1.917
Effects of Simulated Heat Wave and Ozone on High Fat Diet ApoE Deficient Mice

DOI: 10.3967/bes2018.101

Sample: Plasma,Tissue homogenate
MEDICAL SCIENCE MONITOR (2020) IF: 1.918
The Effects of RKI-1447 in a Mouse Model of Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet and in HepG2 Human Hepatocellular Carcinoma Cells Treated with Oleic Acid

DOI: 10.12659/MSM.919220

PMID: 32026851
Sample: Serum,Cell culture supernatant,Tissue homogenate
Molecular Medicine Reports (2018) IF: 1.922
Oral supplementation with ursolic acid ameliorates sepsis-induced acute kidney injury in a mouse model by inhibiting oxidative stress and inflammatory responses

DOI: 10.3892/mmr.2018.8767

Sample: Serum
Molecular Medicine Reports (2018) IF: 1.922
Embelin inhibits abdominal aortic aneurysm through decreasing IL‑6‑induced STAT3 and NF‑κB inactivation

DOI: 10.3892/mmr.2018.9221

Sample: Aortic tissues
Molecular Medicine Reports (2018) IF: 1.922
Dioscin prevents LPS‑induced acute lung injury through inhibiting the TLR4/MyD88 signaling pathway via upregulation of HSP70

DOI: 10.3892/mmr.2018.8667

Sample: Serum,Tissue homogenate
ANDROLOGIA (2020) IF: 1.951
The effectiveness of Hedyotis diffusa Willd extract in a mouse model of experimental autoimmune prostatitis

DOI: 10.1111/and.13913

PMID: 33236398
Sample: serum
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2019)
ROS Generated by Upconversion Nanoparticle-Mediated Photodynamic Therapy Induces Autophagy via PI3K/AKT/ mTOR Signaling Pathway in M1 Peritoneal Macrophage.

DOI: 10.33594/000000093

Sample: peritoneal macrophages
Journal of Biomedical Research (2021)
Protective effects on acute hypoxic-ischemic brain damage in mfat-1 transgenic mice by alleviating neuroinflammation

DOI: 10.7555/JBR.35.20210107

Sample: brain tissue
Biomedical Reports (2020)
Neuroprotective effect of Mulmina™ against chemotherapy‑induced cognitive decline in normal mice Erratum in /10.3892/br.2021.1433

DOI: 10.3892/br.2020.1377

Sample: brain
Advances in Pharmacological and Pharmaceutical Sciences (2020)
Antihypernociceptive, Anxiolytic, and Antidepressant Properties of Aqueous and Ethanol Extracts of Dissotis thollonii Cogn. (Melastomataceae) in Mice

DOI: 10.1155/2020/8886894

PMID: 33015629
Sample: Serum,Tissue homogenate
Advances in Traditional Medicine (2020)
Anti-hypernociceptive effects of methanol extract of Boswellia dalzielii on STZ-induced diabetic neuropathic pain

DOI: 10.1007/s13596-019-00411-y

Sample: serum,sciatic nerves
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH (2021) IF: 0.533
Effect of ganoderic acid on diethylnitrosamine-induced liver cancer in mice

DOI: 10.4314/tjpr.v19i12.23

Sample: serum
Journal of Oleo Science (2015) IF: 0.968
A Comparative Study of the Effects upon LPS Induced Macrophage RAW264.7 Inflammation in vitro of the Lipids of Hippocampus trimaculatus Leach

DOI: 10.5650/jos.ess15190

Sample: Cell culture supernatant

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DOI: 10.1038/s41556-022-00853-8
PMID: 35256775	Sample: serum

DOI: 10.1016/j.bbi.2022.11.013
PMID: 36427810	Sample: serum

DOI: 10.1021/acscentsci.2c01424
PMID: 36968547	Sample: bronchoalveolar lavage fluid (BALF),lung

DOI: 10.1126/scitranslmed.aaz6667
PMID: 33239389	Sample: Cell culture supernatant

DOI: 10.1016/j.cej.2022.140619
	Sample: Bone marrow-derived dendritic cell (BMDC)

DOI: 10.1002/advs.202105391
PMID: 35343654	Sample: sera

DOI: 10.1002/smll.202204388
PMID: 36253133	Sample: kidney

DOI: 10.1016/j.biomaterials.2022.121690
PMID: 35965114	Sample: Brain tissue

DOI: 10.1016/j.bioactmat.2021.07.019
PMID: 34820587	Sample: B16–F10 cells,Red blood cells

DOI: 10.1016/j.apsb.2022.08.012
	Sample: bone marrow neutrophil

DOI: 10.1002/adfm.202001771
	Sample: Serum

DOI: 10.1016/j.apsb.2023.02.017
	Sample: Lymphocytes

DOI: 10.1038/s41413-018-0012-0
	Sample: Serum

DOI: 10.1136/jitc-2022-006226
	Sample: Serum

DOI: 10.1136/jitc-2021-004381
PMID: 35738798	Sample: B16F10 cell-xenograft

DOI: 10.1016/j.jconrel.2022.07.021
PMID: 35870569	Sample: serum

DOI: 10.1016/j.jconrel.2023.01.074
	Sample: brain tissues

DOI: 10.7150/thno.68667
PMID: 35547755	Sample: blood

DOI: 10.1016/j.redox.2022.102367
PMID: 35724543	Sample: serum,Kupffer cell (KCs)

DOI: 10.1007/s12274-022-4591-0
	Sample: RAw 264.7 cell

DOI: 10.1186/s12951-021-00796-6
PMID: 33608025	Sample: Tissue（brain）

DOI: 10.1186/s12951-022-01287-y
PMID: 35168608	Sample: tumor cell

DOI: 10.1016/j.actbio.2023.02.003
	Sample: RAW264.7 cell,osteoclasto

DOI: 10.1016/j.carbpol.2022.120032
PMID: 36184177	Sample: bronchoalveolar fluid,RAW264.7 cell

Mouse TNF-α(Tumor Necrosis Factor Alpha) ELISA Kit

To Purchase E-EL-M3063

Product Details

Properties

Test Principle

Kit components & Storage

Technical Data

Precision

Recovery

Linearity

Target Information

Assay Procedures

Citations

NATURE CELL BIOLOGY (2022) IF: 28.824

BRAIN BEHAVIOR AND IMMUNITY (2022) IF: 19.227

ACS Central Science (2023) IF: 18.728

Science Translational Medicine (2020) IF: 16.304

CHEMICAL ENGINEERING JOURNAL (2022) IF: 16.744

CHEMICAL ENGINEERING JOURNAL (2022) IF: 16.744

CHEMICAL ENGINEERING JOURNAL (2022) IF: 16.744

Advanced Science (2022) IF: 16.806

ADVANCED FUNCTIONAL MATERIALS (2020) IF: 16.836

Small (2023) IF: 15.153

Small (2022) IF: 15.153

BIOMATERIALS (2022) IF: 15.304

Bioactive Materials (2021) IF: 14.593

Bioactive Materials (2021) IF: 14.593

Acta Pharmaceutica Sinica B (2022) IF: 14.903

Acta Pharmaceutica Sinica B (2023) IF: 14.903

Science Advances (2022) IF: 14.957

CHEMICAL ENGINEERING JOURNAL (2022) IF: 13.273

JOURNAL OF PINEAL RESEARCH (2023) IF: 12.081

Bone Research (2018) IF: 12.354

Journal for ImmunoTherapy of Cancer (2023) IF: 12.469

Journal for ImmunoTherapy of Cancer (2022) IF: 12.469

Advanced Healthcare Materials (2022) IF: 11.092

JOURNAL OF CONTROLLED RELEASE (2022) IF: 11.467

JOURNAL OF CONTROLLED RELEASE (2023) IF: 11.467

Theranostics (2022) IF: 11.556

Redox Biology (2022) IF: 11.799

Nano Research (2022) IF: 10.269

ACS Applied Materials & Interfaces (2022) IF: 10.383

ACS Applied Materials & Interfaces (2022) IF: 10.383

JOURNAL OF NANOBIOTECHNOLOGY (2022) IF: 10.435

JOURNAL OF NANOBIOTECHNOLOGY (2021) IF: 10.435

JOURNAL OF NANOBIOTECHNOLOGY (2022) IF: 10.435

Acta Biomaterialia (2023) IF: 10.633

Bioengineering & Translational Medicine (2022) IF: 10.711

CARBOHYDRATE POLYMERS (2022) IF: 10.723

SCIENCE OF THE TOTAL ENVIRONMENT (2023) IF: 10.753

SCIENCE OF THE TOTAL ENVIRONMENT (2022) IF: 10.753

Materials Today Bio (2023) IF: 10.761

Nano-Micro Letters (2019) IF: 9.0429

ACS Applied Materials & Interfaces (2022) IF: 9.2289

CARBOHYDRATE POLYMERS (2019) IF: 9.381

CARBOHYDRATE POLYMERS (2021) IF: 9.381

JOURNAL OF NANOBIOTECHNOLOGY (2023) IF: 9.429

BRITISH JOURNAL OF PHARMACOLOGY (2023) IF: 9.4730

Small (2018) IF: 9.5980

ENVIRONMENTAL POLLUTION (2022) IF: 9.988

ANALYTICAL CHEMISTRY (2022) IF: 8.0079

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 8.025

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 8.025

Journal of Neuroinflammation (2021) IF: 8.3219

Cell Death & Disease (2022) IF: 8.4689

Theranostics (2020) IF: 8.5790

EXPERIMENTAL AND MOLECULAR MEDICINE (2022) IF: 8.718

Cellular and Molecular Gastroenterology and Hepatology (2022) IF: 8.7970

CHEMOSPHERE (2022) IF: 8.943

International Journal of Nanomedicine (2022) IF: 7.033

CNS Neuroscience & Therapeutics (2023) IF: 7.035

FOOD HYDROCOLLOIDS (2020) IF: 7.053

CHEMOSPHERE (2020) IF: 7.086

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022) IF: 7.088

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022) IF: 7.088

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022) IF: 7.088

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2023) IF: 7.129

ACTA PHARMACOLOGICA SINICA (2023) IF: 7.169

CARBOHYDRATE POLYMERS (2020) IF: 7.182

Acta Biomaterialia (2020) IF: 7.242

DOI: 10.1016/j.scitotenv.2023.161416
	Sample: mixed glial cell

DOI: 10.1016/j.scitotenv.2022.157076
PMID: 35780899	Sample: plasma

DOI: 10.1021/acsami.2c04300
	Sample: regenerated wound samples

DOI: 10.1016/j.carbpol.2019.115295
PMID: 31582086	Sample: Cell culture supernatant

DOI: 10.1016/j.carbpol.2021.118211
PMID: 34127215	Sample: Tissue Slice

DOI: 10.1002/smll.201804191
PMID: 30549431	Sample: Serum,Tissue homogenate

DOI: 10.1016/j.envpol.2022.120217
PMID: 36155221	Sample: hippocampi

DOI: 10.1021/acs.analchem.2c01691
PMID: 35920602	Sample: hepatic tissue,epididymal fat tissue

DOI: 10.1016/j.ijbiomac.2022.07.043
PMID: 35835298	Sample: Raw 264.7 macrophages

DOI: 10.1016/j.ijbiomac.2022.07.023
PMID: 35817242	Sample: RAW264.7 cell